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当前位置： 首页 > 产品中心 > acid_base_buffer_solution > StressMarq/Anti-RAF1 Antibody (pSer296)/SPC-1071D-RPE/100-µl
商品详细StressMarq/Anti-RAF1 Antibody (pSer296)/SPC-1071D-RPE/100-µl
StressMarq/Anti-RAF1 Antibody (pSer296)/SPC-1071D-RPE/100-µl
StressMarq/Anti-RAF1 Antibody (pSer296)/SPC-1071D-RPE/100-µl
商品编号： SPC-1071D-RPE
市场价： ¥6780.00
美元价： 4068.00
产地： 美国(厂家直采)
公司：
产品分类： 酸碱缓冲液
公司分类： acid_base_buffer_solution
联系Q Q： 3392242852
电话号码： 4000-520-616
电子邮箱： info@ebiomall.com
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商品介绍

Overview:

Product Name RAF1 Antibody (pSer296)
Description

Rabbit Anti-Human RAF1 (pSer296) Polyclonal

Species Reactivity Human
Applications WB, AM
Antibody Dilution WB (1:250); optimal dilutions for assays should be determined by the user.
Host Species Rabbit
Immunogen Species Human
Immunogen A phospho-specific peptide corresponding to residues surrounding Ser296 of human RAF1 (AA293-299)
Conjugates Alkaline Phosphatase, APC, ATTO 390, ATTO 488, ATTO 565, ATTO 594, ATTO 633, ATTO 655, ATTO 680, ATTO 700, Biotin, FITC, HRP, PE/ATTO 594, PerCP, RPE, Streptavidin, Unconjugated

Properties

Storage Buffer PBS pH7.4, 50% glycerol, 0.025% Thimerosal
Storage Temperature -20ºC
Shipping Temperature Blue Ice or 4ºC
Purification Peptide Affinity Purified
Clonality Polyclonal
Specificity Detects ~73kDa.
Cite This Product StressMarq Biosciences Cat# SPC-1071, RRID: AB_2709677
Certificate of Analysis A 1:250 dilution of SPC-1071 was sufficient for detection of RAF1 (pSer296) in 10 µg of HeLa cell lysate by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.

Biological Description

Alternative Names c Raf Antibody, C-raf Antibody, C-Raf proto-oncogene, serine/threonine kinase Antibody, CMD1NN Antibody, Craf 1 transforming gene Antibody, cRaf Antibody, Craf1 transforming gene Antibody, EC 2.7.11.1 Antibody, kinase Raf1 Antibody, Murine sarcoma 3611 oncogene 1 Antibody, NS5 Antibody, Oncogene MIL Antibody, Oncogene RAF1 Antibody, OTTHUMP00000160218 Antibody, OTTHUMP00000207813 Antibody, OTTHUMP00000209389 Antibody, Protein kinase raf 1 Antibody, Proto-oncogene c-RAF Antibody, Raf 1 Antibody, Raf 1 proto oncogene serine/threonine kinase Antibody, RAF Antibody, Raf proto oncogene serine/threonine protein kinase Antibody, RAF proto-oncogene serine/threonine-protein kinase Antibody, RAF-1 Antibody, RAF1 Antibody, RAF1_HUMAN Antibody, Similar to murine leukemia viral (V-raf-1) oncogene homolog 1 Antibody, TRANSFORMING REPLICATION-DEFECTIVE MURINE RETROVIRUS 3611-MSV Antibody, v raf 1 murine leukemia viral oncogene homolog 1 Antibody, v-raf murine sarcoma viral oncogene homolog 1 Antibody, vraf1 murine leukemia viral oncogene homolog 1 Antibody
Cellular Localization Cytoplasm, Cell membrane, Mitochondrion, Nucleus
Accession Number NP_002871
Gene ID 5894
Swiss Prot P04049
Scientific Background RAF1 is a protein-serine/threonine kinase. RAF-1 is upregulated in many cancers since Ras (an upstream activator of RAF) is mutated/upreguated in many cancers. For example, RAF-1 is over-expressed due to oncogenic ras mutations in about 35% of Non-Small Cell Lung Cancer (NSCLC). A small number of RAF mutations have been found in stomach and mouth tumours. RAF-1 gene amplification was detected in 4% of bladder cancer samples, while deletions at the RAF-1 locus were detected in 2.2% of these samples; these amplifications and deletions were correlated with tumour grade.

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  R-PE (R-Phycoerythrin)
Overview:

  • Broad excitation spectrum
  • High quantum yield
  • Photostable
  • Member of the phycobiliprotein family
  • Isolated from red algae
  • Excellent solubility in water
  • Molecular Weight: 250 kDa

R-PE Datasheet

 R-PE Fluorophore Excitation and Emission SpectraOptical Properties:

λex = 565 nm

λem = 575 nm

εmax = 2.0×106

Φf = 0.84

Brightness = 1.68 x 103

Laser = 488 to 561 nm

Filter set = TRITC

 

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StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究，同时在其他领域也取得了一定成就，包括翻译后修饰，提供甲基化与乙酰基化抗体。其中，细胞应激领域主要包括热休克蛋白（HSP）领域。我们公司不仅在热休克蛋白领域领先全球，而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列，分别涉及抗体、蛋白、酶联免疫吸附试验（ELISA）试剂盒及小分子领域。
公司介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究，同时在其他领域也取得了一定成就，包括翻译后修饰，提供甲基化与乙酰基化抗体。其中，细胞应激领域主要包括热休克蛋白（HSP）领域。我们公司不仅在热休克蛋白领域领先全球，而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列，分别涉及抗体、蛋白、酶联免疫吸附试验（ELISA）试剂盒
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