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当前位置: 首页 > 产品中心 > acid_base_buffer_solution > StressMarq/R(-)-Gossypol/SIH-223-50MG/50-mg
商品详细StressMarq/R(-)-Gossypol/SIH-223-50MG/50-mg
StressMarq/R(-)-Gossypol/SIH-223-50MG/50-mg
StressMarq/R(-)-Gossypol/SIH-223-50MG/50-mg
商品编号: SIH-223-50MG
市场价: ¥10200.00
美元价: 6120.00
产地: 美国(厂家直采)
公司:
产品分类: 酸碱缓冲液
公司分类: acid_base_buffer_solution
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

Overview:

ProductNameR(-)-Gossypol
Description

Bcl-2inhibitor

Purity>98%
CASNo.303-45-7
MolecularFormulaC30H30O8
MolecularWeight518.56

Properties

StorageTemperature-20ºC
ShippingTemperatureShippedAmbient
ProductTypeInducer
SolubilitySolubleto25mMinethanolandinDMSO.
SourceSynthetic
AppearanceDarkYellowSolid
SMILESCC1=CC2=C(C(=C(C(=C2C(C)C)O)O)C=O)C(=C1C3=C(C4=C(C=C3C)C(=C(C(=C4C=O)O)O)C(C)C)O)O
InChIInChI=1S/C30H30O8/c1-11(2)19-15-7-13(5)21(27(35)23(15)17(9-31)25(33)29(19)37)22-14(6)8-16-20(12(3)4)30(38)26(34)18(10-32)24(16)28(2
InChIKeyQBKSWRVVCFFDOT-UHFFFAOYSA-N
SafetyPhrasesClassification:Harmful.Maybeharmfulifinhaled,swallowedorabsorbedthroughskin.SafetyPhrases:S22-DonotbreathedustS24/25-AvoidcontactwithskinandeyesS36/37/39-Wearsuitableprotectiveclothing,glovesandeye/faceprotectionRiskPhrases:R62-PossIBLeriskofimpairedfertilityR68-PossibleriskofirreversibleeffectsHazardPhrases:H351PrecautionaryPhrases:P281
CiteThisProductR(-)-Gossypol(StressMarqBiosciencesInc.,VictoriaBCCANADA,Catalog#SIH-223)

BIOLOGicalDescription

AlternativeNames1,1",6,6",7,7"-Hexahydroxy-5,5"-diisopropyl-3,3"-dimethyl-2,2"-binaphthalene-8,8"-dicarbaldehyde,Gossypol
ResearchAreasCancer,Apoptosis
PubChemID3503
ScientificBackgroundGossypolisanaturalphenolderivedfromthecottonplant,andisaphenolicaldehydethatpermeatescellsandactsasaninhibitorforseveraldehydrogenaseenzymes.Ithasproapoptoticproperties,duetotheregulationoftheBaxandBcl2.Italsoreversiblyinhibitscalcineurinandbindstocalmodulin(1,2).
References1.www.bioscreening.net“Gossypol”
2.CarruthersN.J.,DowdM.K.,andStemmerP.M.(2007)EurJPharmacol.555(2-3):106-114.

ProductImages

<p>Chemical structure of R(-)-Gossypol (SIH-223), a Bcl-2 inhibitor. CAS #: 303-45-7. Molecular Formula: C30H30O8. Molecular Weight: 518.56 g/mol.</p>

ChemicalstructureofR(-)-Gossypol(SIH-223),aBcl-2inhibitor.CAS#:303-45-7.MolecularFormula:C30H30O8.MolecularWeight:518.56g/mol.

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品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究,同时在其他领域也取得了一定成就,包括翻译后修饰,提供甲基化与乙酰基化抗体。其中,细胞应激领域主要包括热休克蛋白(HSP)领域。我们公司不仅在热休克蛋白领域领先全球,而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列,分别涉及抗体、蛋白、酶联免疫吸附试验(ELISA)试剂盒及小分子领域。