应力MARQ/Pyr3/SIH-306-10MG/10MG
商品编号：
SIH-306-10MG
市场价：
¥2460.00
美元价：
1476.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Overview:
| ProductName | Pyr3 |
| Description | TRPC3Channelblocker |
| Purity | >98% |
| CASNo. | 1160514-60-2 |
| MolecularFormula | C16H11Cl3F3N3O3 |
| MolecularWeight | 456.63 |
Properties
| StorageTemperature | -20ºC |
| ShippingTemperature | ShippedAmbient |
| ProductType | Inhibitor |
| Solubility | Solubleto100mMinDMSO |
| Source | Synthetic |
| Appearance | WhiteSolid |
| SMILES | CCOC(=O)C1=C(N(N=C1)C2=CC=C(C=C2)NC(=O)C(=C(Cl)Cl)Cl)C(F)(F)F |
| InChI | InChI=1S/C16H11Cl3F3N3O3/c1-2-28-15(27)10-7-23-25(12(10)16(20,21)22)9-5-3-8(4-6-9)24-14(26)11(17)13(18)19/h4-7H,2H2,1H3,(H,24,26) |
| InChIKey | RZHGONNSASQOAY-UHFFFAOYSA-N |
| SafetyPhrases | Classification:Caution:Substancenotyetfullytested.SafetyPhrases:S22-DonotbreathedustS24/25-AvoidcontactwithskinandeyesS36/37/39-Wearsuitableprotectiveclothing,glovesandeye/faceprotection |
| CiteThisProduct | Pyr3(StressMarqBiosciencesInc.,VictoriaBCCANADA,Catalog#SIH-306) |
BIOLOGicalDescription
| AlternativeNames | Ethyl1-{4-[(2,3,3-trichloroacryloyl)amino]phenyl}-5-(trifluoromethyl)-1H-pyrazole-4-carboxylate |
| ResearchAreas | IonChannels,Neuroscience,TransientReceptorPotentialChannels |
| PubChemID | 56964346 |
| ScientificBackground | Pyr3,anovelpyrazole,selectivelyinhibitsTRPC3channels.InBlymphocytes,Pyr3eliminatedtheBcellreceptor-inducedCa2+oscillationregulatedbyTRPC3-mediatedCa2+influx.Inthecardiacsystem,Pyr3attenuatesactivationofnuclearfactorofactivatedTcellsandhypertrophicgrowthinmyocytesandpressureoverloaded-inducedhypertrophyinvivo(1). |
| References | 1.KiyonakaS.,KatoK.,NishidaM.,andMoriY.(2010)YakugakuZasshi.130(3):303-311. |
ProductImages
ChemicalstructureofPyr3(SIH-306),aTRPC3Channelblocker.CAS#:1160514-60-2.MolecularFormula:C16H11Cl3F3N3O3.MolecularWeight:456.63g/mol.
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品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究，同时在其他领域也取得了一定成就，包括翻译后修饰，提供甲基化与乙酰基化抗体。其中，细胞应激领域主要包括热休克蛋白（HSP）领域。我们公司不仅在热休克蛋白领域领先全球，而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列，分别涉及抗体、蛋白、酶联免疫吸附试验（ELISA）试剂盒及小分子领域。
