StressMarq/PX 866/SIH-471-5MG/5-mg
商品编号：
SIH-471-5MG
市场价：
¥3300.00
美元价：
1980.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Overview:
| ProductName | PX866 |
| Description | PI3-Kinaseinhibitor |
| Purity | >98% |
| CASNo. | 502632-66-8 |
| MolecularFormula | C29H35NO8 |
| MolecularWeight | 525.6 |
Properties
| StorageTemperature | -20ºC |
| ShippingTemperature | ShippedAmbient |
| ProductType | Inhibitor |
| Solubility | SolubleinDMSOat200mg/ml;solubleinethanolat200mg/ml;verypoorlysolubleinwater |
| Source | Synthetic |
| Appearance | Crystallinesolid |
| SMILES | CC(=O)O[[email protected]@H]1C[[email protected]]2([[email protected]@H](CCC2=O)C3=C1[[email protected]]4([[email protected]](OC(=O)/C(=C/N(CC=C)CC=C)/C4=C(C3=O)O)COC)C)C |
| InChI | InChI=1S/C29H35NO8/c1-7-11-30(12-8-2)14-17-23-26(34)25(33)22-18-9-10-20(32)28(18,4)13-19(37-16(3)31)24(22)29(23,5)21(15-36-6)38-27(17)35/h7-8,14,18-19,21,34H,1-2,9-13,15H2,3-6H3/b17-14+/t18-,19+,21+, |
| InChIKey | QIUASFSNWYMDFS-NILGECQDSA-N |
| SafetyPhrases | Classification:AcuteToxicity:Inhalation,Category4AcuteToxicity:Oral,Category4AcuteToxicity:Skin,Category4SkinCorrosion/Irritation,Category2SeriousEyeDamage/EyeIrritation,Category2SafetyPhrases:S22-Donotbreathedust.S24/25-Avoidcontactwithskinandeyes.S36/37/39-Wearsuitableprotectiveclothing,glovesandeye/faceprotection.Hazardstatements:H332:Harmfulifinhaled.H302:Harmfulifswallowed.H312:Harmfulincontactwithskin.H315:Causesskinirritation.H319:Causesseriouseyeirritation.Precautionarystatements:P261:Avoidbreathing{dust/fume/gas/mist/vapours/spray}.P264:Wash{hands}thoroughlyafterhandling.P280:Wear{protectivegloves/protectiveclothing/eyeprotection/faceprotection}.P362+364:Takeoffcontaminatedclothingandwashitbeforereuse.P304+340:IFINHALED:Removevictimtofreshairandkeepatrestinapositioncomfortableforbreathing.P312:Calla{POISONCENTER/doctor/...}ifyoufeelunwell.P301+312:IFSWALLOWED:CallaPOISONCENTERordoctor/physicianifyoufeelunwell.P330:Rinsemouth.P302+352:IFONSKIN:Washwithplentyofsoapandwater.P321:Specifictreatment{see...onthislabel}.P332+313:Ifskinirritationoccurs,getmedicaladvice/attention.P305+351+338:IFINEYES:Rinsecautiouslywithwaterforseveralminutes.Removecontactlenses,ifpresentandeasytodo.Continuerinsing.P337+313:Ifeyeirritationpersists,getmedicaladvice/attention. |
| CiteThisProduct | PX866(StressMarqBiosciencesInc.,VictoriaBCCANADA,Catalog#SIH-471) |
BIOLOGicalDescription
| AlternativeNames | (1E,4S,4aR,5R,6aS,9aR)-5-(acetyloxy)-1-[(di-2-propen-1-ylamino)methylene]-4,4a,5,6,6a,8,9,9a-octahydro-11-hydroxy-4-(methoxymethyl)-4a,6a-dimethyl-cyclopenta[5,6]naphtho[1,2-c]pyran-2,7,10(1H)-trione |
| ResearchAreas | Cancer,Apoptosis,CancerGrowthInhibitors,CellSignaling,TyrosineKinaseInhibitors |
| PubChemID | 9849735 |
| ScientificBackground | PX866isawortmanninderivativethatinhibitspurifiedphosphoinositide(PtdIns)-3-kinaseand.PX866hasbeenshowntoinhibittumorgrowthbyblockingthePI3-kinasepathwayandcellmotility. |
| References | 1.IhleN.T.,etal.(2004).Mol.Cancer.Ther.3(7):763–772. 2.GwakH.S.,etal.(2011).Int.J.Cancer.128(4):787–796. |
ProductImages
ChemicalstructureofPX866(SIH-471),aPI3-Kinaseinhibitor.CAS#:502632-66-8.MolecularFormula:C29H35NO8.MolecularWeight:525.6g/mol.
ProductCitations(0)
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品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究，同时在其他领域也取得了一定成就，包括翻译后修饰，提供甲基化与乙酰基化抗体。其中，细胞应激领域主要包括热休克蛋白（HSP）领域。我们公司不仅在热休克蛋白领域领先全球，而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列，分别涉及抗体、蛋白、酶联免疫吸附试验（ELISA）试剂盒及小分子领域。
