StressMarq/PX 866/SIH-471-1MG/1-mg
商品编号：
SIH-471-1MG
市场价：
¥1500.00
美元价：
900.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Overview:
| Product Name | PX 866 |
| Description | PI 3-Kinase inhibitor |
| Purity | >98% |
| CAS No. | 502632-66-8 |
| Molecular Formula | C29H35NO8 |
| Molecular Weight | 525.6 |
Properties
| Storage Temperature | -20ºC |
| Shipping Temperature | Shipped Ambient |
| Product Type | Inhibitor |
| Solubility | Soluble in DMSO at 200 mg/ml; soluble in ethanol at 200 mg/ml; very poorly soluble in water |
| Source | Synthetic |
| Appearance | Crystalline solid |
| SMILES | CC(=O)O[[email protected]@H]1C[[email protected]]2([[email protected]@H](CCC2=O)C3=C1[[email protected]]4([[email protected]](OC(=O)/C(=C/N(CC=C)CC=C)/C4=C(C3=O)O)COC)C)C |
| InChI | InChI=1S/C29H35NO8/c1-7-11-30(12-8-2)14-17-23-26(34)25(33)22-18-9-10-20(32)28(18,4)13-19(37-16(3)31)24(22)29(23,5)21(15-36-6)38-27(17)35/h7-8,14,18-19,21,34H,1-2,9-13,15H2,3-6H3/b17-14+/t18-,19+,21+, |
| InChIKey | QIUASFSNWYMDFS-NILGECQDSA-N |
| Safety Phrases | Classification: Acute Toxicity: Inhalation, Category 4 Acute Toxicity: Oral, Category 4 Acute Toxicity: Skin, Category 4 Skin Corrosion/Irritation, Category 2 Serious Eye Damage/Eye Irritation, Category 2Safety Phrases: S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.Hazard statements: H332: Harmful if inhaled. H302: Harmful if swallowed. H312: Harmful in contact with skin. H315: Causes skin irritation. H319: Causes serious eye irritation.Precautionary statements: P261: Avoid breathing {dust/fume/gas/mist/vapours/spray}. P264: Wash {hands} thoroughly after handling. P280: Wear {protective gloves/protective clothing/eye protection/face protection}. P362+364: Take off contaminated clothing and wash it before reuse. P304+340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P312: Call a {POISON CENTER/doctor/...} if you feel unwell. P301+312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. P330: Rinse mouth. P302+352: IF ON SKIN: Wash with plenty of soap and water. P321: Specific treatment {see ... on this label}. P332+313: If skin irritation occurs, get medical advice/attention. P305+351+338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P337+313: If eye irritation persists, get medical advice/attention. |
| Cite This Product | PX 866 (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-471) |
Biological Description
| Alternative Names | (1E,4S,4aR,5R,6aS,9aR)-5-(acetyloxy)-1-[(di-2-propen-1-ylamino)methylene]-4,4a,5,6,6a,8,9,9a-octahydro-11-hydroxy-4-(methoxymethyl)-4a,6a-dimethyl-cyclopenta[5,6]naphtho[1,2-c]pyran-2,7,10(1H)-trione |
| Research Areas | Cancer, Apoptosis, Cancer Growth Inhibitors, Cell Signaling, Tyrosine Kinase Inhibitors |
| PubChem ID | 9849735 |
| Scientific Background | PX 866 is a wortmannin derivative that inhibits purified phosphoinositide (PtdIns)-3-kinase and. PX 866 has been shown to inhibit tumor growth by blocking the PI 3-kinase pathway and cell motility. |
| References |
1. Ihle N.T., et al. (2004). Mol. Cancer. Ther. 3(7): 763–772. 2. Gwak H.S., et al. (2011). Int. J. Cancer. 128(4): 787–796. |
Product Images
Chemical structure of PX 866 (SIH-471), a PI 3-Kinase inhibitor. CAS #: 502632-66-8. Molecular Formula: C29H35NO8. Molecular Weight: 525.6 g/mol.
Product Citations (0)
Currently there are no citations for this product.
品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究，同时在其他领域也取得了一定成就，包括翻译后修饰，提供甲基化与乙酰基化抗体。其中，细胞应激领域主要包括热休克蛋白（HSP）领域。我们公司不仅在热休克蛋白领域领先全球，而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列，分别涉及抗体、蛋白、酶联免疫吸附试验（ELISA）试剂盒及小分子领域。
