StressMarq/Puromycin HCl/SIH-248-250MG/250-mg
商品编号：
SIH-248-250MG
市场价：
¥3200.00
美元价：
1920.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Overview:
| ProductName | PuromycinHCl |
| Description | Translationinhibitor |
| Purity | >98%(TLC);NMR(Conforms) |
| CASNo. | 58-58-2 |
| MolecularFormula | C22H29N7O5•2HCl |
| MolecularWeight | 544.43 |
Properties
| StorageTemperature | -20ºC |
| ShippingTemperature | ShippedAmbient |
| ProductType | Inhibitor |
| Solubility | MaybedissolvedinDMSO(50mg/ml);orwater(50mg/ml) |
| Source | Synthetic |
| Appearance | Off-whitepowder |
| SMILES | CN(C)C1=NC=NC2=C1N=CN2[[email protected]]3[[email protected]@H]([[email protected]@H]([[email protected]](O3)CO)NC(=O)[[email protected]](CC4=CC=C(C=C4)OC)N)O |
| InChI | InChI=1S/C22H29N7O5/c1-28(2)19-17-20(25-10-24-19)29(11-26-17)22-18(31)16(15(9-30)34-22)27-21(32)14(23)8-12-4-6-13(33-3)7-5 |
| InChIKey | RXWNCPJZOCPEPQ-WABMVTPESA-N |
| SafetyPhrases | Classification:Harmful.Maybeharmfulifinhaled,swallowedorabsorbedthroughskin.SafetyPhrases:S22-DonotbreathedustS24/25-AvoidcontactwithskinandeyesS36/37/39-Wearsuitableprotectiveclothing,glovesandeye/faceprotection |
| CiteThisProduct | PuromycinHCl(StressMarqBiosciencesInc.,VictoriaBCCANADA,Catalog#SIH-248) |
BIOLOGicalDescription
| AlternativeNames | 3"-Deoxy-N,N-dimethyl-3"-[(O-methyl-L-tyrosyl)amino]adenosine |
| ResearchAreas | Cancer,Apoptosis |
| PubChemID | 5891 |
| ScientificBackground | Puromycinisanantibioticthatisaproteinsynthesisinhibitorthatcausesprematurechainterminationduringtranslationtakingplaceintheribosome.Partofthemoleculeresemblesthe3’endofthetRNA.ItenterstheAsiteandtransferstothegrowingchain,causingtheprematurerelease.Itisnotselectiveforeitherprokaryotesoreukaryotes. |
| References | 1. AzzamandAlgranati.(1973)ProcNatlAcadSci.70:3866. |
ProductImages
ChemicalstructureofPuromycinHCl(SIH-248),aTranslationinhibitor.CAS#:58-58-2.MolecularFormula:C22H29N7O5x2HCl.MolecularWeight:544.43g/mol.
ProductCitations(2)
OtherCitations
Housingtemperature-inducedstressdrivestherapeuticresistanceinmurinetumourmodelsthroughβ2-adrenergicreceptoractivation.
Eng,J.W.etal.(2015)NatCommun.6:6426.
PubMedID:25756236Applications:Cellselectionmedia
LaminB2preventschromosomeinstABIlitybyensuringpropermitoticchromosomesegregation.
Kuga,T.etal.(2014)Oncogenesis.3:e94.
PubMedID:24637494Applications:siRNAselectionmedia
品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究，同时在其他领域也取得了一定成就，包括翻译后修饰，提供甲基化与乙酰基化抗体。其中，细胞应激领域主要包括热休克蛋白（HSP）领域。我们公司不仅在热休克蛋白领域领先全球，而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列，分别涉及抗体、蛋白、酶联免疫吸附试验（ELISA）试剂盒及小分子领域。
