应力MARQ/PP2/SIH-470-25MG/25MG
商品编号：
SIH-470-25MG
市场价：
¥12000.00
美元价：
7200.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Overview:
| ProductName | PP2 |
| Description | Srckinaseinhibitor |
| Purity | >98%(TLC) |
| CASNo. | 172889-27-9 |
| MolecularFormula | C15H16ClN5 |
| MolecularWeight | 301.8 |
Properties
| StorageTemperature | -20ºC |
| ShippingTemperature | ShippedAmbient |
| ProductType | Inhibitor |
| Solubility | SolubleinDMSO(25mg/ml) |
| Source | Synthetic |
| Appearance | Off-whitesolid |
| SMILES | C1=C(C=CC(=C1)Cl)C2=N[N](C3=C2C(=NC=N3)N)C(C)(C)C |
| InChI | InChI=1S/C15H16ClN5/c1-15(2,3)21-14-11(13(17)18-8-19-14)12(20-21)9-4-6-10(16)7-5-9/h4-8H,1-3H3,(H2,17,18,19) |
| InChIKey | PBBRWFOVCUAONR-UHFFFAOYSA-N |
| SafetyPhrases | Classification:AcuteToxicity:Oral,Category3SafetyPhrases:S22-Donotbreathedust.S24/25-Avoidcontactwithskinandeyes.S36/37/39-Wearsuitableprotectiveclothing,glovesandeye/faceprotection.Hazardstatements:H301:Toxicifswallowed.Precautionarystatements:P264:Wash{hands}thoroughlyafterhandling.P301+310:IFSWALLOWED:ImmediatelycallaPOISONCENTERordoctor/physician.P330:Rinsemouth |
| CiteThisProduct | PP2(StressMarqBiosciencesInc.,VictoriaBCCANADA,Catalog#SIH-470) |
BIOLOGicalDescription
| AlternativeNames | 3-(4-chlorophenyl)1-(1,1-dimethylethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine |
| ResearchAreas | Cancer,Apoptosis,CancerGrowthInhibitors,CellSignaling,TyrosineKinaseInhibitors |
| PubChemID | 4878 |
| ScientificBackground | PP2isaselectiveinhibitorofSrc-familytyrosinekinases.PP2hasbeenshowntoinhibitLck,FynT,andphosphorylationoffocaladhesionkinase(FAK)andpotentlyinhibitsHck,Lck(p56)andFyn(p59).PP2displays>10000-foldselectivityoverZAP-70andJAK2. |
| References | 1.HankeJ.H.,etal.(1996)J.Biol.Chem.271(2):695–701. 2.LiuY.,etal.(1999).Chem.&Biol.6(9):671–678. |
ProductImages
ChemicalstructureofPP2(SIH-470),aSrcfamilykinaseinhibitor.CAS#:172889-27-9.MolecularFormula:C15H16ClN5.MolecularWeight:301.8g/mol.
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品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究，同时在其他领域也取得了一定成就，包括翻译后修饰，提供甲基化与乙酰基化抗体。其中，细胞应激领域主要包括热休克蛋白（HSP）领域。我们公司不仅在热休克蛋白领域领先全球，而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列，分别涉及抗体、蛋白、酶联免疫吸附试验（ELISA）试剂盒及小分子领域。
