StressMarq/PP1/SIH-469-25MG/25-mg
商品编号：
SIH-469-25MG
市场价：
¥9900.00
美元价：
5940.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Overview:
| Product Name | PP1 |
| Description | Src kinase inhibitor |
| Purity | >98% (TLC) |
| CAS No. | 172889-26-8 |
| Molecular Formula | C16H19N5 |
| Molecular Weight | 281.4 |
Properties
| Storage Temperature | -20ºC |
| Shipping Temperature | Shipped Ambient |
| Product Type | Inhibitor |
| Solubility | Soluble in DMSO (25 mg/ml), slightly soluble in 100% ethanol |
| Source | Synthetic |
| Appearance | Tan solid |
| SMILES | CC1=CC=C(C=C1)C2=NN(C3=NC=NC(=C23)N)C(C)(C)C |
| InChI | InChI=1S/C16H19N5/c1-10-5-7-11(8-6-10)13-12-14(17)18-9-19-15(12)21(20-13)16(2,3)4/h5-9H,1-4H3,(H2,17,18,19) |
| InChIKey | ZVPDNRVYHLRXLX-UHFFFAOYSA-N |
| Safety Phrases | Classification: Acute toxicity, Oral (Category 3), H301Safety Phrases: S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.Hazard statements: H301 Toxic if swallowed.Precautionary statements: P264 Wash skin thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P301 + P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/ physician. P321 Specific treatment (see supplemental first aid instructions on this label). P330 Rinse mouth. P405 Store locked up. P501 Dispose of contents/ container to an approved waste disposal plant. |
| Cite This Product | PP1 (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-469) |
Biological Description
| Alternative Names | 1-(1,1-Dimethylethyl)-1-(4-methylphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine |
| Research Areas | Cancer, Apoptosis, Cancer Growth Inhibitors, Cell Signaling, Tyrosine Kinase Inhibitors |
| PubChem ID | 1400 |
| Scientific Background | PP1 is a potent and selective Src family protein tyrosine kinase inhibitor. This has a range of effects and implications. Structural studies have revealed that PP1 binds to the ATP-binding site in tyrosine kinases and Ser/Thr kinases. PP1 displays > 8000-fold selectivity over ZAP-70 and JAK2. |
| References |
1. Hanke J.H., et al. (1996) J. Biol. Chem. 271(2): 695–701. 2. Liu Y., et al. (1999). Chem. & Biol. 6(9): 671–678. |
Product Images
Chemical structure of PP1 (SIH-469), a Src family kinase inhibitor. CAS #: 172889-26-8. Molecular Formula: C16H19N5. Molecular Weight: 281.4 g/mol.
Product Citations (0)
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品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究，同时在其他领域也取得了一定成就，包括翻译后修饰，提供甲基化与乙酰基化抗体。其中，细胞应激领域主要包括热休克蛋白（HSP）领域。我们公司不仅在热休克蛋白领域领先全球，而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列，分别涉及抗体、蛋白、酶联免疫吸附试验（ELISA）试剂盒及小分子领域。
