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当前位置: 首页 > 产品中心 > acid_base_buffer_solution > StressMarq/PP1/SIH-469-5MG/5-mg
商品详细StressMarq/PP1/SIH-469-5MG/5-mg
StressMarq/PP1/SIH-469-5MG/5-mg
StressMarq/PP1/SIH-469-5MG/5-mg
商品编号: SIH-469-5MG
市场价: ¥2500.00
美元价: 1500.00
产地: 美国(厂家直采)
公司:
产品分类: 酸碱缓冲液
公司分类: acid_base_buffer_solution
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

Overview:

ProductNamePP1
Description

Srckinaseinhibitor

Purity>98%(TLC)
CASNo.172889-26-8
MolecularFormulaC16H19N5
MolecularWeight281.4

Properties

StorageTemperature-20ºC
ShippingTemperatureShippedAmbient
ProductTypeInhibitor
SolubilitySolubleinDMSO(25mg/ml),slightlysolublein100%ethanol
SourceSynthetic
AppearanceTansolid
SMILESCC1=CC=C(C=C1)C2=NN(C3=NC=NC(=C23)N)C(C)(C)C
InChIInChI=1S/C16H19N5/c1-10-5-7-11(8-6-10)13-12-14(17)18-9-19-15(12)21(20-13)16(2,3)4/h5-9H,1-4H3,(H2,17,18,19)
InChIKeyZVPDNRVYHLRXLX-UHFFFAOYSA-N
SafetyPhrasesClassification:Acutetoxicity,Oral(Category3),H301SafetyPhrases:S22-Donotbreathedust.S24/25-Avoidcontactwithskinandeyes.S36/37/39-Wearsuitableprotectiveclothing,glovesandeye/faceprotection.Hazardstatements:H301Toxicifswallowed.Precautionarystatements:P264Washskinthoroughlyafterhandling.P270Donoteat,drinkorsmokewhenusingthisproduct.P301+P310IFSWALLOWED:ImmediatelycallaPOISONCENTERordoctor/physician.P321Specifictreatment(seesupplementalfirstaidinstructionsonthislabel).P330Rinsemouth.P405Storelockedup.P501Disposeofcontents/containertoanapprovedwastedisposalplant.
CiteThisProductPP1(StressMarqBiosciencesInc.,VictoriaBCCANADA,Catalog#SIH-469)

BIOLOGicalDescription

AlternativeNames1-(1,1-Dimethylethyl)-1-(4-methylphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
ResearchAreasCancer,Apoptosis,CancerGrowthInhibitors,CellSignaling,TyrosineKinaseInhibitors
PubChemID1400
ScientificBackgroundPP1isapotentandselectiveSrcfamilyproteintyrosinekinaseinhibitor.Thishasarangeofeffectsandimplications.StructuralstudieshaverevealedthatPP1bindstotheATP-bindingsiteintyrosinekinasesandSer/Thrkinases.PP1displays>8000-foldselectivityoverZAP-70andJAK2.
References1.HankeJ.H.,etal.(1996)J.Biol.Chem.271(2):695–701.
2.LiuY.,etal.(1999).Chem.&Biol.6(9):671–678.

ProductImages

<p>Chemical structure of PP1 (SIH-469), a Src family kinase inhibitor. CAS #: 172889-26-8. Molecular Formula: C16H19N5. Molecular Weight: 281.4 g/mol.</p>

ChemicalstructureofPP1(SIH-469),aSrcfamilykinaseinhibitor.CAS#:172889-26-8.MolecularFormula:C16H19N5.MolecularWeight:281.4g/mol.

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品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究,同时在其他领域也取得了一定成就,包括翻译后修饰,提供甲基化与乙酰基化抗体。其中,细胞应激领域主要包括热休克蛋白(HSP)领域。我们公司不仅在热休克蛋白领域领先全球,而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列,分别涉及抗体、蛋白、酶联免疫吸附试验(ELISA)试剂盒及小分子领域。