应力MARQ/PJ-34/SIH-366-50MG/50MG
商品编号：
SIH-366-50MG
市场价：
¥12880.00
美元价：
7728.00
产品分类：
其它缓冲液
公司分类：
Other_buffers
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Overview:
| ProductName | PJ-34 |
| Description | PARPinhibitor |
| Purity | >98%(HPLC);NMR(conforms) |
| CASNo. | 344458-15-7 |
| MolecularFormula | C17H17N3O2•HCL•H2O |
| MolecularWeight | 331.8 |
Properties
| StorageTemperature | -20ºC |
| ShippingTemperature | ShippedAmbient |
| ProductType | Inhibitor |
| Solubility | MaybedissolvedinDMSO(30mg/ml)orwater(20mg/ml) |
| Source | Synthetic |
| Appearance | Whitetoyellowsolid. |
| SMILES | CN(C)CC(=O)NC1=CC2=C(C=C1)NC(=O)C3=CC=CC=C32.Cl |
| InChI | InChI=1S/C17H17N3O2/c1-20(2)10-16(21)18-11-7-8-15-14(9-11)12-5-3-4-6-13(12)17(22)19-15/h4-9H,10H2,1-2H3,(H,18,21)(H,19,22) |
| InChIKey | UYJZZVDLGDDTCL-UHFFFAOYSA-N |
| SafetyPhrases | Classification:Caution:Substancenotyetfullytested.SafetyPhrases:S22-DonotbreathedustS24/25-AvoidcontactwithskinandeyesS36/37/39-Wearsuitableprotectiveclothing,glovesandeye/faceprotection |
| CiteThisProduct | PJ-34(StressMarqBiosciencesInc.,VictoriaBCCANADA,Catalog#SIH-366) |
BIOLOGicalDescription
| AlternativeNames | N-(6-Oxo-5,6-dihydrophenanthridin-2-yl)-N,Ndimethylacetamide.HCl |
| ResearchAreas | Cancer,Apoptosis,CancerGrowthInhibitors,PARPInhibitors |
| PubChemID | 4858 |
| ScientificBackground | PJ-34isaselectiveinhibitorofPoly(ADP-Ribose)polymerase(PARP).StudieshaveshownthattheuseofPJ-34onsevereinflammatorydiseases,inparticularexperimentalallergicencephalomyelitis(EAE)havecontributedtoashiftoftheimmuneresponsefromapro-inflammatoryTh1toanti-inflammatoryth2phenotype(1). |
| References | 1.ScottG.,KeanR.,Mikheeva.,FABIsM.,MableyJ.J.(2004)TheJournalofPharmacologyandExp.Therapeutics.310(3):1053-1061. |
ProductImages
ChemicalstructureofPJ-34(SIH-366),aPARPinhibitor.CAS#:344458-15-7.MolecularFormula:C17H17N3O2*HCL*H2O.MolecularWeight:331.8g/mol.
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品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究，同时在其他领域也取得了一定成就，包括翻译后修饰，提供甲基化与乙酰基化抗体。其中，细胞应激领域主要包括热休克蛋白（HSP）领域。我们公司不仅在热休克蛋白领域领先全球，而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列，分别涉及抗体、蛋白、酶联免疫吸附试验（ELISA）试剂盒及小分子领域。
