STRESTMARQ/抗PINX1抗体/SPC-1330D-P594/100-µl-免疫在线蚂蚁淘旗下平台

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商品详细STRESTMARQ/抗PINX1抗体/SPC-1330D-P594/100-µl

STRESTMARQ/抗PINX1抗体/SPC-1330D-P594/100-µl

商品编号： SPC-1330D-P594

品牌： StressMarq Biosciences

市场价： ¥6180.00

美元价： 3708.00

产地：美国(厂家直采)

公司：

产品分类：其它缓冲液

公司分类： Other_buffers

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Overview:

ProductName PINX1Antibody

Description

RabbitAnti-HumanPINX1Polyclonal

SpeciesReactivity Human

Applications IHC,ELISA

AntibodyDilution IHC(1:100),ELISA(1:20000);optimaldilutionsforassaysshouldbedeterminedbytheuser.

HostSpecies Rabbit

ImmunogenSpecies Human

Immunogen SynthesizedpeptidederivedfrominternalofhumanPINX1.

Conjugates

AlkalinePhosphatase,APC,ATTO390,ATTO488,ATTO565,ATTO594,ATTO633,ATTO655,ATTO680,ATTO700,Biotin,FITC,HRP,PE/ATTO594,PerCP,RPE,Streptavidin,Unconjugated

Properties

StorageBuffer	PBSpH7.4,50%glycerol,150mMNaCl,0.02%sodiumazide
StorageTemperature	-20ºC
ShippingTemperature	BlueIceor4ºC
Purification	AffinityPurified
Clonality	Polyclonal
Isotype	IgG
Specificity	DetectsendogenouslevelsoftotalPINX1protein.
CiteThisProduct	StressMarqBiosciencesCat#SPC-1330,RRID:AB_2713727
CertificateofAnalysis	A1:100dilutionofSPC-1330wassufficientfordetectionofPINX1inhumanhearttissueusingGoatAnti-RabbitIgGasthesecondaryantibody.

BIOLOGicalDescription

AlternativeNames	67-11-3proteinantibody,FLJ20565antibody,Hepatocellularcarcinoma-relatedputativetumorsuppressorantibody,Liver-relatedputativetumorsuppressorantibody,LPTLantibody,LPTSantibody,MGC8850antibody,OTTHUMP00000224984antibody,OTTHUMP00000224985antibody,OTTHUMP00000224986antibody,OTTHUMP00000225053antibody,OTTHUMP00000225054antibody,PIN2interactingprotein1antibody,Pin2-interactingproteinX1antibody,PIN2/TERF1-interactingtelomeraseinhibitor1antibody,PINX1antibody,PINX1_HUMANantibody,Protein67-11-3antibody,TRF1-interactingprotein1antibody
CellularLocalization	Chromosome,Nucleus
AccessionNumber	NP_060354.4
GeneID	54984
SwissProt	Q96BK5
ScientificBackground	PIN2/TERF1-interactingtelomeraseinhibitor1,alsoknownasPINX1,isahumangene.ItmediatesTRF1andTERTaccumulationinnucleolusandenhancesTRF1bindingtotelomeres,inhibitstelomeraseactivity.itmayalsoinhibitcellproliferationandactastumorsuppressor.Over-expressionofPINX1resultsindecreasedtelomeraseactivity,telomereshortening,andinductionofcrisis.ReductionofPINX1leadstoanincreaseintelomeraseactivityandelongationoftelomeres.PINX1differsfromotherproteinsthatregulatetelomerelengthinthatitactsontelomerasewhileotherproteinsadjusttelomerelengthwithoutaffectingtelomeraseactivity.
References	1.SongH.etal.(2004)Biochem.Biophys.Res.Commun.(UnitedStates)316(4):1116–23. 2.Soohoo,C.Y.(2010)JournalofBiologicalChemistry. 3.Yoo,J.E.(2009)JournalofMolecularBiology. 4.Zhou,X.Z.(2011)JournalofClinicalInvestigation.

ProductImages

<p>Immunohistochemistry analysis using Rabbit Anti-PINX1 Polyclonal Antibody (SPC-1330). Tissue: Heart Tissue. Species: Human. Fixation: Formalin fixed paraffin-embedded. Primary Antibody: Rabbit Anti-PINX1 Polyclonal Antibody (SPC-1330) at 1:100. The image on the right is treated with the synthesized peptide.</p>

ImmunohistochemistryanalysisusingRabbitAnti-PINX1PolyclonalAntibody(SPC-1330).Tissue:HeartTissue.Species:Human.Fixation:Formalinfixedparaffin-embedded.PrimaryAntibody:RabbitAnti-PINX1PolyclonalAntibody(SPC-1330)at1:100.Theimageontherightistreatedwiththesynthesizedpeptide.

ProductCitations(0)

Currentlytherearenocitationsforthisproduct.

PE/ATTO594

PE/ATTO594isatandemconjugate,wherePEisexcitedat535nmandtransfersenergytoATTO594viaFRET(fluorescenceresonanceenergytransfer),whichemitsat627nm.

Overview:

Highfluorescenceyield
HighphotostABIlity
Veryhydrophilic
Excellentsolubilityinwater
Verylittleaggregation

PE/ATTO594Datasheet

PE-ATTO 594 Fluorophore Conjugate Excitation and Emission Spectra

OpticalProperties:

λ_ex =535nm

λ_em =627 nm

Laser = 488to561nm

品牌介绍

StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究，同时在其他领域也取得了一定成就，包括翻译后修饰，提供甲基化与乙酰基化抗体。其中，细胞应激领域主要包括热休克蛋白（HSP）领域。我们公司不仅在热休克蛋白领域领先全球，而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列，分别涉及抗体、蛋白、酶联免疫吸附试验（ELISA）试剂盒及小分子领域。

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