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当前位置: 首页 > 产品中心 > Other_buffers > STRESTMARQ/抗短笛抗体/SPC-197S/12-µg
商品详细STRESTMARQ/抗短笛抗体/SPC-197S/12-µg
STRESTMARQ/抗短笛抗体/SPC-197S/12-µg
STRESTMARQ/抗短笛抗体/SPC-197S/12-µg
商品编号: SPC-197S
市场价: ¥800.00
美元价: 480.00
产地: 美国(厂家直采)
公司:
产品分类: 其它缓冲液
公司分类: Other_buffers
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

Overview:

ProductNamePiccoloAntibody
Description

RabbitAnti-HumanPiccoloPolyclonal

SpeciesReactivityHuman,Mouse,Rat
ApplicationsWB,IHC
AntibodyDilutionWB(1:1000),IHC(1:400);optimaldilutionsforassaysshouldbedeterminedbytheuser.
HostSpeciesRabbit
ImmunogenSpeciesHuman
ImmunogenFulllengthprotein,BC001304.1
Concentration1mg/ml
ConjugatesAlkalinePhosphatase,APC,ATTO390,ATTO488,ATTO565,ATTO594,ATTO633,ATTO655,ATTO680,ATTO700,Biotin,FITC,HRP,PE/ATTO594,PerCP,RPE,Streptavidin,Unconjugated

Properties

StorageBufferPBSpH7.4,50%glycerol,0.09%sodiumazide
StorageTemperature-20ºC
ShippingTemperatureBlueIceor4ºC
PurificationProteinApurified
ClonalityPolyclonal
SpecificityDetects~550kDa.Nocross-reactivitytoBassoon.
CiteThisProductStressMarqBiosciencesCat#SPC-197,RRID:AB_10804537
CertificateofAnalysis1µg/mlofSPC-197wassufficientfordetectionofPiccoloin10µgofratbraintissuelysatebycolorimetricimmunoblotanalysisusinggoatantrabbitIgG:HRPasthesecondaryantibody.

BIOLOGicalDescription

AlternativeNamesACZAntibody,AczoninAntibody,Brain-derivedHLMNproteinAntibody,DKFZp779G1236Antibody,KIAA0559Antibody,MultidomainpresynapticcytomatrixproteinAntibody,PCLOAntibody,PCLO_HUMANAntibody,Piccolo(presynapticcytomatrixprotein)Antibody,PiccolomousehomologofPicoAntibody,PresynapticcytomatrixproteinAntibody,ProteinpiccoloAntibody
ResearchAreasCellMarkers,NeuronMarkers,Neuroscience,PresynapticMarkers
CellularLocalizationCellJunction,Synapse
AccessionNumberNP_055325.2
GeneID27445
SwissProtQ9Y6VO
ScientificBackgroundPiccolo,alsoreferredtoasAczonin,isalargeproteinwhichconsistsofanN-terminalZn2+finger,severalpiccolo-bassoonhomologydomainsandC-terminalPDZandC2domains(1,2).Ingeneralitisfoundtogetherwithbassoon,arelatedhugemulti-domainproteinoftheCAZ(cytoskeletalmatricassembledatactivezones)(3).Piccoloisascaffoldingproteinforproteinsinvolvedinendo-andexocytosisofsynapticvesicles.PiccolohasalsobeenshowntointerferewithclathrinmedicatedendocytosisbybindingtotheF-actinanddynaminbindingproteinAbp1(2).
References1.GerberS.H.,GarciaJ.,RizoJ.,SudhofT.C.(2001)EMBOJ.20(7):1605-1619.
2.WangX.,etal.(1999)JCellBiol.147(1):151-162.
3.DresbachT.,etal.(2006)JBiolChem.281(9):6038-6047.

ProductImages

<p>Immunohistochemistry analysis using Rabbit Anti-Piccolo Polyclonal Antibody (SPC-197). Tissue: Muscle. Species: Mouse. Primary Antibody: Rabbit Anti-Piccolo Polyclonal Antibody (SPC-197) at 1:400. Secondary Antibody: Alexa Fluor 488 Goat Anti-Rabbit. Counterstain: BTX (red). Localization: Selective staining of the NMJ.</p>

ImmunohistochemistryanalysisusingRabbitAnti-PiccoloPolyclonalAntibody(SPC-197).Tissue:Muscle.Species:Mouse.PrimaryAntibody:RabbitAnti-PiccoloPolyclonalAntibody(SPC-197)at1:400.SecondaryAntibody:AlexaFluor488GoatAnti-Rabbit.Counterstain:BTX(red).Localization:SelectivestainingoftheNMJ.

<p>Western blot analysis of Mouse, Rat brain cell lysates showing detection of Piccolo protein using Rabbit Anti-Piccolo Polyclonal Antibody (SPC-197). Primary Antibody: Rabbit Anti-Piccolo Polyclonal Antibody (SPC-197) at 1:1000.</p>

WesternblotanalysisofMouse,RatbraincelllysatesshowingdetectionofPiccoloproteinusingRabbitAnti-PiccoloPolyclonalAntibody(SPC-197).PrimaryAntibody:RabbitAnti-PiccoloPolyclonalAntibody(SPC-197)at1:1000.

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品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究,同时在其他领域也取得了一定成就,包括翻译后修饰,提供甲基化与乙酰基化抗体。其中,细胞应激领域主要包括热休克蛋白(HSP)领域。我们公司不仅在热休克蛋白领域领先全球,而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列,分别涉及抗体、蛋白、酶联免疫吸附试验(ELISA)试剂盒及小分子领域。