StressMarq/Phenylbutyrate Na/SIH-255-500MG/500-mg
商品编号：
SIH-255-500MG
市场价：
¥1120.00
美元价：
672.00
产品分类：
其它缓冲液
公司分类：
Other_buffers
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Overview:
| ProductName | PhenylbutyrateNa |
| Description | HDACinhibitor |
| Purity | >98% |
| CASNo. | 1716-12-7 |
| MolecularFormula | C10H11NaO2 |
| MolecularWeight | 186.18 |
Properties
| StorageTemperature | -20ºC |
| ShippingTemperature | ShippedAmbient |
| ProductType | Inducer |
| Solubility | Solubleto1100mMinwaterand100mMinDMSO |
| Source | Synthetic |
| Appearance | Whitesolid |
| SMILES | C1=CC=C(C=C1)CCCC(=O)[O-].[Na+] |
| InChI | InChI=1S/C10H12O2.Na/c11-10(12)8-4-7-9-5-2-1-3-6-9;/h1-3,5-6H,4,7-8H2,(H,11,12);/q;+1/p-1 |
| InChIKey | VPZRWNZGLKXFOE-UHFFFAOYSA-M |
| SafetyPhrases | Classification:Harmful.Maybeharmfulifinhaled,swallowedorabsorbedthroughskin.SafetyPhrases:S22-DonotbreathedustS24/25-AvoidcontactwithskinandeyesS36/37/39-Wearsuitableprotectiveclothing,glovesandeye/faceprotection |
| CiteThisProduct | PhenylbutyrateNa(StressMarqBiosciencesInc.,VictoriaBCCANADA,Catalog#SIH-255) |
BIOLOGicalDescription
| AlternativeNames | Sodium4-phenylbutanoate,4-PB |
| ResearchAreas | Cancer,Apoptosis,CancerGrowthInhibitors,HDACInhibitors |
| PubChemID | 5258 |
| ScientificBackground | Sodiumphenylbutyrateismetabolizedinthehumanbodybybeta-oxidationtophenylacetate,whichisthenconjugatedwithglutaminetophenylacetylglutamine,whichiseliminatedwithurine(1).Itinhibitscellproliferation,invasionandmigrationandinducesapoptosisingliomacells.Italsoinhibitsproteinisoprenylation,depletesplasmaglutamine,increasesproductionoffetalhemoglobinthroughtranscriptionalactivationofgamma-globingene(2). |
| References | 1.BatashawM.L.,MacArthurR.B.,andTuchmanM.(2001)JPediatr.138:S46-54. 2.MelicharB.,etal.(1998)ClinCancerRes.4:3069-3076. |
ProductImages
ChemicalstructureofPhenylbutyrateNa(SIH-255),aHistonedeacetylaseinhibitor.CAS#:1716-12-7.MolecularFormula:C10H11NaO2.MolecularWeight:186.18g/mol.
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品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究，同时在其他领域也取得了一定成就，包括翻译后修饰，提供甲基化与乙酰基化抗体。其中，细胞应激领域主要包括热休克蛋白（HSP）领域。我们公司不仅在热休克蛋白领域领先全球，而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列，分别涉及抗体、蛋白、酶联免疫吸附试验（ELISA）试剂盒及小分子领域。
