StressMarq/PHA 665752/SIH-421-5MG/5-mg
商品编号：
SIH-421-5MG
市场价：
¥2300.00
美元价：
1380.00
产品分类：
其它缓冲液
公司分类：
Other_buffers
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Overview:
| ProductName | PHA665752 |
| Description | METkinaseinhibitor |
| Purity | >98% |
| CASNo. | 477575-56-7 |
| MolecularFormula | C32H34Cl2N4O4S |
| MolecularWeight | 641.61 |
Properties
| StorageTemperature | -20ºC |
| ShippingTemperature | ShippedAmbient |
| ProductType | Inhibitor |
| Solubility | Solubleto100mMinDMSO. |
| Source | Synthetic |
| Appearance | Yellowsolid |
| SMILES | ClC1=C(C(=CC=C1)Cl)C[S](=O)(=O)C3=CC=C2NC(C(/C2=C3)=CC4=C(C(=C([NH]4)C)C(=O)N5CCC[[email protected]@H]5CN6CCCC6)C)=O |
| InChI | InChI=1S/C32H34Cl2N4O4S/c1-19-29(35-20(2)30(19)32(40)38-14-6-7-21(38)17-37-12-3-4-13-37)16-24-23-15-22(10-11-28(23)36-31(24)39)43(41,42)18-25-26(33)8-5-9-27(25)34/h5,8-11,15-16,21,35H,3-4,6-7,12-14,1 |
| InChIKey | OYONTEXKYJZFHA-SSHUPFPWSA-N |
| SafetyPhrases | Classification:NotWHMIScontrolled.SafetyPhrases:S22-Donotbreathedust.S24/25-Avoidcontactwithskinandeyes.S36/37/39-Wearsuitableprotectiveclothing,glovesandeye/faceprotection. |
| CiteThisProduct | PHA665752(StressMarqBiosciencesInc.,VictoriaBCCANADA,Catalog#SIH-421) |
BIOLOGicalDescription
| AlternativeNames | (2R)-1-[[5-[(Z)-[5-[[(2,6-Dichlorophenyl)methyl]sulfonyl]-1,2-dihydro-2-oxo-3H-indol-3-ylidene]methyl]-2,4-dimethyl-1H-pyrrol-3-yl]carbonyl]-2-(1-pyrrolidinylmethyl)pyrrolidine |
| ResearchAreas | Cancer,Apoptosis,CancerGrowthInhibitors,CellSignaling,TyrosineKinaseInhibitors |
| PubChemID | 10461815 |
| ScientificBackground | PHA665752isapotentandselectiveMETkinase,ATP-competitiveinhibitor.IthasbeenstudiedasanantitumoragentbecauseithasbeenseentoinhibittumOrigenicityandangiogenesisinmouselungcancerxenografts. |
| References | 1.PuriN.,KhramtsovA.,AhmedS.,NallasuraV.,HetzelJ.,JagadeeswaranR.,etal.(2007)CancerRes.3529-34. |
ProductImages
ChemicalstructureofPHA665752(SIH-421),aMETkinaseinhibitor.CAS#:477575-56-7.MolecularFormula:C32H34Cl2N4O4S.MolecularWeight:641.61g/mol.
ProductCitations(0)
Currentlytherearenocitationsforthisproduct.
品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究，同时在其他领域也取得了一定成就，包括翻译后修饰，提供甲基化与乙酰基化抗体。其中，细胞应激领域主要包括热休克蛋白（HSP）领域。我们公司不仅在热休克蛋白领域领先全球，而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列，分别涉及抗体、蛋白、酶联免疫吸附试验（ELISA）试剂盒及小分子领域。
