StressMarq/PD98059/SIH-466-5MG/5-mg
商品编号：
SIH-466-5MG
市场价：
¥1600.00
美元价：
960.00
产品分类：
其它缓冲液
公司分类：
Other_buffers
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Overview:
| ProductName | PD98059 |
| Description | MEKkinaseinhibitor |
| Purity | >95%(HPLC) |
| CASNo. | 167869-21-8 |
| MolecularFormula | C16H13NO3 |
| MolecularWeight | 267.3 |
Properties
| StorageTemperature | -20ºC |
| ShippingTemperature | ShippedAmbient |
| ProductType | Inhibitor |
| Solubility | SolubleinDMSO(6.5mg/ml);25mg/mlinanhydrousDMSO),methanol,dichlormethaneand100%ethanol(0.6mg/ml) |
| Source | Synthetic |
| Appearance | Paleyellowsolid |
| SMILES | COC1=CC=CC(=C1N)C2=CC(=O)C3=CC=CC=C3O2 |
| InChI | InChI=1S/C16H13NO3/c1-19-14-8-4-6-11(16(14)17)15-9-12(18)10-5-2-3-7-13(10)20-15/h2-9H,17H2,1H3 |
| InChIKey | QFWCYNPOPKQOKV-UHFFFAOYSA-N |
| SafetyPhrases | Classification:Acutetoxicity,Oral(Category3),H301SafetyPhrases:S22-Donotbreathedust.S24/25-Avoidcontactwithskinandeyes.S36/37/39-Wearsuitableprotectiveclothing,glovesandeye/faceprotection.Hazardstatements:H301Toxicifswallowed.Precautionarystatements:P264Washskinthoroughlyafterhandling.P270Donoteat,drinkorsmokewhenusingthisproduct.P301+P310IFSWALLOWED:ImmediatelycallaPOISONCENTERordoctor/physician.P321Specifictreatment(seesupplementalfirstaidinstructionsonthislabel).P330Rinsemouth.P405Storelockedup.P501Disposeofcontents/containertoanapprovedwastedisposalplant. |
| CiteThisProduct | PD98059(StressMarqBiosciencesInc.,VictoriaBCCANADA,Catalog#SIH-466) |
BIOLOGicalDescription
| AlternativeNames | 2-(2-Amino-3-methoxyphenyl)-4H-1-benzopyran-4-one,PD98059 |
| ResearchAreas | Cancer,Apoptosis,CancerGrowthInhibitors,CellSignaling,TyrosineKinaseInhibitors |
| PubChemID | 4713 |
| ScientificBackground | PD98059isapotent,selectiveandreversIBLeinhibitorofmitogen-activatedproteinkinasekinase(MAPKK/MEK-1)activation.Specifically,itbindstotheinactiveformofMAPKK,blockingitsactivation,causinginhibitionofphosphorylationandtheactivationofMAPkinase.Ithasbeenshowntoenhanceself-renewalofembryonicstemcells.PD98059iscellpermeableinhibitor. |
| References | 1.AlessiD.R.,CuendaA.,CohenP.,DudleyD.T.,&SaltielA.R.(1995)J.Biol.Chem.270(46):27489–27494. 2.QiX.,etal.(2004)Pro.Nat.Acad.Sci.USA.101(16):6027–6032. 3.DudleyD.T.,PangL.,DeckerS.J.,BridgesA.J.,&SaltielA.R.(1995)Pro.Nat.Acad.Sci.USA.92(17):7686–7689. |
ProductImages
ChemicalstructureofPD98059(SIH-466),aMEKkinaseinhibitor.CAS#:167869-21-8.MolecularFormula:C16H13NO3.MolecularWeight:267.3g/mol.
ProductCitations(0)
Currentlytherearenocitationsforthisproduct.
品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究，同时在其他领域也取得了一定成就，包括翻译后修饰，提供甲基化与乙酰基化抗体。其中，细胞应激领域主要包括热休克蛋白（HSP）领域。我们公司不仅在热休克蛋白领域领先全球，而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列，分别涉及抗体、蛋白、酶联免疫吸附试验（ELISA）试剂盒及小分子领域。
