StressMarq/PD325901/SIH-507-25MG/25-mg
商品编号：
SIH-507-25MG
市场价：
¥7100.00
美元价：
4260.00
产品分类：
其它缓冲液
公司分类：
Other_buffers
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Overview:
| ProductName | PD325901 |
| Description | MEKkinaseinhibitor |
| Purity | >98%(HPLC) |
| CASNo. | 391210-10-9 |
| MolecularFormula | C16H14F3IN2O4 |
| MolecularWeight | 482.2 |
Properties
| StorageTemperature | -20ºC |
| ShippingTemperature | ShippedAmbient |
| ProductType | Inhibitor |
| Solubility | Solubleto25mMinDMSO |
| Source | Synthetic |
| Appearance | Off-whitesolid |
| SMILES | C1=CC(=C(C=C1I)F)NC2=C(C=CC(=C2F)F)C(=O)NOC[[email protected]@H](CO)O |
| InChI | InChI=1S/C16H14F3IN2O4/c17-11-3-2-10(16(25)22-26-7-9(24)6-23)15(14(11)19)21-13-4-1-8(20)5-12(13)18/h1-5,9,21,23-24H,6-7H2,(H,22,25)/t9-/m1/s1 |
| InChIKey | SUDAHWBOROXANE-SECBINFHSA-N |
| SafetyPhrases | Classification:Acutetoxicity,Oral(Category3),H301Specifictargetorgantoxicity-repeatedexposure(Category2),H373Acuteaquatictoxicity(Category1),H400Chronicaquatictoxicity(Category1),H410SafetyPhrases:S22-Donotbreathedust.S24/25-Avoidcontactwithskinandeyes.S36/37/39-Wearsuitableprotectiveclothing,glovesandeye/faceprotection.Hazardstatements:H301Toxicifswallowed.H373Maycausedamagetoorgansthroughprolongedorrepeatedexposure.H410Verytoxictoaquaticlifewithlonglastingeffects.Precautionarystatements:P260Donotbreathedust/fume/gas/mist/vapours/spray.P264Washskinthoroughlyafterhandling.P270Donoteat,drinkorsmokewhenusingthisproduct.P273Avoidreleasetotheenvironment.P301+P310IFSWALLOWED:ImmediatelycallaPOISONCENTERordoctor/physician.P314Getmedicaladvice/attentionifyoufeelunwell.P321Specifictreatment(seesupplementalfirstaidinstructionsonthislabel).P330Rinsemouth.P391Collectspillage.P405Storelockedup.P501Disposeofcontents/containertoanapprovedwastedisposalplant. |
| CiteThisProduct | PD325901(StressMarqBiosciencesInc.,VictoriaBCCANADA,Catalog#SIH-507) |
BIOLOGicalDescription
| AlternativeNames | PD0325901,PD-325901,N-[(2R)-2,3-Dihydroxypropoxy]-3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]-benzamide |
| ResearchAreas | Cancer,Apoptosis,CancerGrowthInhibitors,CellSignaling,TyrosineKinaseInhibitors |
| PubChemID | 9826528 |
| ScientificBackground | PD325901isapotentMEK1andMEK2inhibitor.Specifically,ithasbeenshowntosuppressphosphorylationofERK1/2inmurinecolon26cells,aswellas,itsdownstreamtarget,ribosomalS6kinase,inadose-dependentmanner. |
| References | 1.BarrettS.D.,etal.(2008)Bioorganic.Med.Chem.Letters.18(24):6501–6504. 2.CiuffredaL.,etal.(2009)Neoplasia.11(8):720–731. |
ProductImages
ChemicalstructureofPD325901(SIH-507),aMEKkinaseinhibitor.CAS#:391210-10-9.MolecularFormula:C16H14F3IN2O4.MolecularWeight:482.2g/mol.
ProductCitations(0)
Currentlytherearenocitationsforthisproduct.
品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究，同时在其他领域也取得了一定成就，包括翻译后修饰，提供甲基化与乙酰基化抗体。其中，细胞应激领域主要包括热休克蛋白（HSP）领域。我们公司不仅在热休克蛋白领域领先全球，而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列，分别涉及抗体、蛋白、酶联免疫吸附试验（ELISA）试剂盒及小分子领域。
