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当前位置: 首页 > 产品中心 > Other_buffers > StressMarq/Anti-p38a Antibody (pThr180+pTyr182)/SPC-1037D-A633/100-µl
商品详细StressMarq/Anti-p38a Antibody (pThr180+pTyr182)/SPC-1037D-A633/100-µl
StressMarq/Anti-p38a Antibody (pThr180+pTyr182)/SPC-1037D-A633/100-µl
StressMarq/Anti-p38a Antibody (pThr180+pTyr182)/SPC-1037D-A633/100-µl
商品编号: SPC-1037D-A633
市场价: ¥6840.00
美元价: 4104.00
产地: 美国(厂家直采)
公司:
产品分类: 其它缓冲液
公司分类: Other_buffers
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

Overview:

ProductNamep38aAntibody(pThr180+pTyr182)
Description

RabbitAnti-Humanp38a(pThr180+pTyr182)Polyclonal

SpeciesReactivityHuman
ApplicationsWB,AM
AntibodyDilutionWB(1:250);optimaldilutionsforassaysshouldbedeterminedbytheuser.
HostSpeciesRabbit
ImmunogenSpeciesHuman
ImmunogenAphospho-specificpeptidecorrespondingtoresiduessurroundingThr180andTyr182ofhumanp38a(AA177-182)
ConjugatesAlkalinePhosphatase,APC,ATTO390,ATTO488,ATTO565,ATTO594,ATTO633,ATTO655,ATTO680,ATTO700,Biotin,FITC,HRP,PE/ATTO594,PerCP,RPE,Streptavidin,Unconjugated

Properties

StorageBufferPBSpH7.4,50%glycerol,0.025%Thimerosal
StorageTemperature-20ºC
ShippingTemperatureBlueIceor4ºC
PurificationPeptideAffinityPurified
ClonalityPolyclonal
SpecificityDetects41.293kDa.
CiteThisProductStressMarqBiosciencesCat#SPC-1037,RRID:AB_2709065
CertificateofAnalysisA1:250dilutionofSPC-1037wassufficientfordetectionofp38a(pThr180+pTyr182)in10µgofHeLacelllysatebyECLimmunoblotanalysisusinggoatanti-rabbitIgG:HRPasthesecondaryantibody.

BIOLOGicalDescription

AlternativeNamesCSAID-bindingproteinantibody,Csaidsbindingproteinantibody,CSBP1antibody,CSBP2antibody,Cytokinesuppressiveanti-inflammatorydrug-bindingproteinantibody,EXIPantibody,MAPkinase14antibody,MAPkinaseMXI2antibody,MAPkinasep38alphaantibody,MAPK14antibody,MAXinteractingprotein2antibody,MitogenActivatedProteinKinase14antibody,Mitogenactivatedproteinkinasep38alphaantibody,Mitogen-activatedproteinkinase14antibody,Mitogen-activatedproteinkinasep38alphaantibody,MK14_HUMANantibody,Mxi2antibody,p38ALPHAantibody,p38antibody,p38MAPkinaseantibody,p38MAPKantibody,p38mitogenactivatedproteinkinaseantibody,p38ALPHAantibody,p38alphaExipantibody,PRKM14antibody,SAPK2Aantibody
CellularLocalizationCytoplasm,Nucleus
AccessionNumberNP_620581
GeneID1432
SwissProtQ16539
ScientificBackgroundMAPK14isaprotein-serine/threoninekinasethatisactivatedbypro-inflammatorycytokines,environmentalstressandLPS,viaphosphorylationbyMAPkinasekinases,orautophosphorylation.ItssubstratesincludethetranscriptionregulatorsATF2,MEF2C,andMAX;thecellcycleregulatorCDC25B;andp53,whichindicatesthatMAPK14playsaroleinstress-relatedtranscriptionandincellcycleregulation,aswellasinthegenotoxicstressresponse.Itisakeyplayerinthemaintenanceofhematopoiesishomeostasis,asitbalancesbothproliferativeandgrowthinhibitorysignalsfromgrowthfactors/cytokinesthatregulatehematopoiesis.Alterationsinthiscontrolledbalancecouldresultineitheroverproductionordepletionofmyelosuppressivecytokines,whichcouldleadtothedevelopmentofvarioustypesofbonemarrowfailures.

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 ATTO633
Overview:
  • Highfluorescenceyield
  • HighthermalandphotostABIlity
  • Moderatelyhydrophilic
  • Goodsolubilityinpolarsolvents
  • StableatpH4–11
  • Cationicdye,perchloratesalt
  • MolarMass:652.2g/mol

ATTO633Datasheet

ATTO 633 Fluorophore Absorption and Emission SpectrumOpticalProperties:

λex =629nm

λem=657nm

εmax=1.3×105

Φf= 0.64

τfl =3.2ns

Brightness=83.2

Laser =633 nm

Filterset =Cy®5

 

品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究,同时在其他领域也取得了一定成就,包括翻译后修饰,提供甲基化与乙酰基化抗体。其中,细胞应激领域主要包括热休克蛋白(HSP)领域。我们公司不仅在热休克蛋白领域领先全球,而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列,分别涉及抗体、蛋白、酶联免疫吸附试验(ELISA)试剂盒及小分子领域。