StressMarq/NVPBEZ235/SIH-465-25MG/25-mg
商品编号：
SIH-465-25MG
市场价：
¥4500.00
美元价：
2700.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Overview:
| ProductName | NVPBEZ235 |
| Description | PI3-kinaseinhibitor |
| Purity | >97% |
| CASNo. | 915019-65-7 |
| MolecularFormula | C30H23N5O |
| MolecularWeight | 469.5 |
Properties
| StorageTemperature | -20ºC |
| ShippingTemperature | ShippedAmbient |
| ProductType | Inhibitor |
| Solubility | Solubleinchloroform(1mg/ml),1-methyl-2-pyrrolidnone(2mg/mlat75°C),DMSO(1.33mg/ml),andDMF(10mg/mlat75°C) |
| Source | Synthetic |
| Appearance | Crystallinesolid |
| SMILES | CC(C)(C#N)C1=CC=C(C=C1)N2C3=C4C=C(C=CC4=NC=C3N(C2=O)C)C5=CC6=CC=CC=C6N=C5 |
| InChI | InChI=1S/C30H23N5O/c1-30(2,18-31)22-9-11-23(12-10-22)35-28-24-15-19(21-14-20-6-4-5-7-25(20)32-16-21)8-13-26(24)33-17-27(28)34(3)29(35)36/h4-17H,1-3H3 |
| InChIKey | JOGKUKXHTYWRGZ-UHFFFAOYSA-N |
| SafetyPhrases | Classification:Skinirritation(Category2)Eyeirritation(Category2)Respiratorytractirritation(Category3)SafetyPhrases:S22-Donotbreathedust.S24/25-Avoidcontactwithskinandeyes.S36/37/39-Wearsuitableprotectiveclothing,glovesandeye/faceprotection.Hazardstatements:H302+H312Harmfulifswallowedorincontactwithskin.H315Causesskinirritation.H319Causesseriouseyeirritation.H332Harmfulifinhaled.H335Maycauserespiratoryirritation.Precautionarystatements:P261Avoidbreathingdust/fume/gas/mist/vapours/spray.P264Washhandsthoroughlyafterhandling.P301+P312IFSWALLOWED:CallaPOISONCENTERordoctor/physicianifyoufeelunwell.P302+P352IFONSKIN:Washwithplentyofsoapandwater.P304+P340IFINHALED:Removevictimtofreshairandkeepatrestinapositioncomfortableforbreathing.P305+P351+P338IFINEYES:Rinsecautiouslywithwaterforseveralminutes.Removecontactlenses,ifpresentandeasytodo.Continuerinsing.P332+P313Ifskinirritationoccurs:Getmedicaladvice/attention.P337+P313Ifeyeirritationpersists:Getmedicaladvice/attention.P363Washcontaminatedclothingbeforereuse.P501Disposeofcontents/containertoanapprovedwastedisposalplant. |
| CiteThisProduct | NVPBEZ235(StressMarqBiosciencesInc.,VictoriaBCCANADA,Catalog#SIH-465) |
BIOLOGicalDescription
| AlternativeNames | 4-[2,3-dihydro-3-methyl-2-oxo-8-(3-quinolinyl)-1H-imidazo[4,5-c]quinolin-1-yl]-α,α-dimethyl-benzeneacetonitrile |
| ResearchAreas | Cancer,Apoptosis,CancerGrowthInhibitors,CellSignaling,TyrosineKinaseInhibitors |
| PubChemID | 11977753 |
| ScientificBackground | NVPBEZ235isaspecificPI3-kinase(PI3K)tyrosinekinaseinhibitor,whichshowsdualPI3K/mTORinhibition.NVPBEZ235hasalsobeenshowntoinhibitATR.Ithasdemonstratedantiproliferativeactivityagainsttumorcelllinesinanimalmodelsofcancer. |
| References | 1.YasumizuY.,etal.(2014)J.Urology.191(1):227–234. 2.ShorttJ.,etal.(2013)Blood.121(15):2964–2974. |
ProductImages
ChemicalstructureofNVPBEZ235(SIH-465),aPI3-kinaseinhibitor.CAS#:915019-65-7.MolecularFormula:C30H23N5O.MolecularWeight:469.5g/mol.
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品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究，同时在其他领域也取得了一定成就，包括翻译后修饰，提供甲基化与乙酰基化抗体。其中，细胞应激领域主要包括热休克蛋白（HSP）领域。我们公司不仅在热休克蛋白领域领先全球，而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列，分别涉及抗体、蛋白、酶联免疫吸附试验（ELISA）试剂盒及小分子领域。
