StressMarq/Nutlin-3/SIH-344-25MG/25-mg
商品编号：
SIH-344-25MG
市场价：
¥10600.00
美元价：
6360.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Overview:
| ProductName | Nutlin-3 |
| Description | p53/mdm2inhibitor |
| Purity | >98% |
| CASNo. | 548472-68-0 |
| MolecularFormula | C30H30Cl2N4O4 |
| MolecularWeight | 581.9 |
Properties
| StorageTemperature | -20ºC |
| ShippingTemperature | ShippedAmbient |
| ProductType | Inhibitor |
| Solubility | Solublein100mMDMSOandEthanol |
| Source | Synthetic |
| Appearance | Yellowsolid |
| SMILES | CC(C)OC1=C(C=CC(=C1)OC)C2=N[[email protected]]([[email protected]](N2C(=O)N3CCNC(=O)C3)C4=CC=C(C=C4)Cl)C5=CC=C(C=C5)Cl |
| InChI | InChI=1S/C30H30Cl2N4O4/c1-18(2)40-25-16-23(39-3)12-13-24(25)29-34-27(19-4-8-21(31)9-5-19)28(20-6-10-22(32)11-7-20)36(29)30(38)35-15-14-33-26(37)17-35/h4-13,16,18,27-28H,14-15,17H2,1-3H3,(H,33,37) |
| InChIKey | BDUHCSBCVGXTJM-UHFFFAOYSA-N |
| SafetyPhrases | Classification:Caution–Substancenotyetfullytested.SafetyPhrases:S22-DonotbreathedustS36/37/39-Wearsuitableprotectiveclothing,glovesandeye/faceprotectionS24/25-Avoidcontactwithskinandeyes |
| CiteThisProduct | Nutlin-3(StressMarqBiosciencesInc.,VictoriaBCCANADA,Catalog#SIH-344) |
BIOLOGicalDescription
| AlternativeNames | (±)-4-[4,5-Bis(4-chlorophenyl)-2-(2-isopropoxy-4-methoxy-phenyl)-4,5-dihydro-imidazole-1-carbonyl]-piperazin-2-one |
| ResearchAreas | Cancer,Apoptosis,CancerGrowthInhibitors,p53/mdm2Inhibitors |
| PubChemID | 216345 |
| ScientificBackground | MDM2antagoNIST;inhibitstheMDM2-p53interaction(IC50=0.09µM)andactivatesp53.Antiproliferativeagent;inducesapoptosisincancercells. |
| References | 1.Vassilevetal(2004)Science303:844. |
ProductImages
ChemicalstructureofNutlin-3(SIH-344),ap53/mdm2inhibitor.CAS#:548472-68-0.MolecularFormula:C30H30Cl2N4O4.MolecularWeight:581.9g/mol.
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品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究，同时在其他领域也取得了一定成就，包括翻译后修饰，提供甲基化与乙酰基化抗体。其中，细胞应激领域主要包括热休克蛋白（HSP）领域。我们公司不仅在热休克蛋白领域领先全球，而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列，分别涉及抗体、蛋白、酶联免疫吸附试验（ELISA）试剂盒及小分子领域。
