StressMarq/Nutlin-3/SIH-344-5MG/5-mg
商品编号：
SIH-344-5MG
市场价：
¥2980.00
美元价：
1788.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Overview:
| Product Name | Nutlin-3 |
| Description | p53/mdm2 inhibitor |
| Purity | >98% |
| CAS No. | 548472-68-0 |
| Molecular Formula | C30H30Cl2N4O4 |
| Molecular Weight | 581.9 |
Properties
| Storage Temperature | -20ºC |
| Shipping Temperature | Shipped Ambient |
| Product Type | Inhibitor |
| Solubility | Soluble in 100 mM DMSO and Ethanol |
| Source | Synthetic |
| Appearance | Yellow solid |
| SMILES | CC(C)OC1=C(C=CC(=C1)OC)C2=N[[email protected]]([[email protected]](N2C(=O)N3CCNC(=O)C3)C4=CC=C(C=C4)Cl)C5=CC=C(C=C5)Cl |
| InChI | InChI=1S/C30H30Cl2N4O4/c1-18(2)40-25-16-23(39-3)12-13-24(25)29-34-27(19-4-8-21(31)9-5-19)28(20-6-10-22(32)11-7-20)36(29)30(38)35-15-14-33-26(37)17-35/h4-13,16,18,27-28H,14-15,17H2,1-3H3,(H,33,37) |
| InChIKey | BDUHCSBCVGXTJM-UHFFFAOYSA-N |
| Safety Phrases | Classification: Caution – Substance not yet fully tested. Safety Phrases: S22 - Do not breathe dust S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection S24/25- Avoid contact with skin and eyes |
| Cite This Product | Nutlin-3 (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-344) |
Biological Description
| Alternative Names | (±)-4-[4,5-Bis(4-chlorophenyl)-2-(2-isopropoxy-4-methoxy-phenyl)-4,5- dihydro-imidazole -1-carbonyl]-piperazin-2-one |
| Research Areas | Cancer, Apoptosis, Cancer Growth Inhibitors, p53/mdm2 Inhibitors |
| PubChem ID | 216345 |
| Scientific Background | MDM2 antagonist; inhibits the MDM2-p53 interaction (IC50 = 0.09 µM) and activates p53. Antiproliferative agent; induces apoptosis in cancer cells. |
| References | 1. Vassilev et al (2004) Science 303: 844. |
Product Images
Chemical structure of Nutlin-3 (SIH-344), a p53/mdm2 inhibitor. CAS #: 548472-68-0. Molecular Formula: C30H30Cl2N4O4. Molecular Weight: 581.9 g/mol.
Product Citations (0)
Currently there are no citations for this product.
品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究，同时在其他领域也取得了一定成就，包括翻译后修饰，提供甲基化与乙酰基化抗体。其中，细胞应激领域主要包括热休克蛋白（HSP）领域。我们公司不仅在热休克蛋白领域领先全球，而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列，分别涉及抗体、蛋白、酶联免疫吸附试验（ELISA）试剂盒及小分子领域。
