StressMarq/NSC-66811/SIH-338-50MG/50-mg
商品编号：
SIH-338-50MG
市场价：
¥10600.00
美元价：
6360.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Overview:
| ProductName | NSC-66811 |
| Description | p53/mdm2inhibitor |
| Purity | >98% |
| CASNo. | 6964-62-1 |
| MolecularFormula | C23H20N2O |
| MolecularWeight | 340.4 |
Properties
| StorageTemperature | -20ºC |
| ShippingTemperature | ShippedAmbient |
| ProductType | Inhibitor |
| Solubility | Solublein25mg/mlDMSO |
| Source | Synthetic |
| Appearance | WhiteSolid |
| SMILES | CC1=NC2=C(C=C1)C=CC(=C2O)C(C3=CC=CC=C3)NC4=CC=CC=C4 |
| InChI | InChI=1S/C23H20N2O/c1-16-12-13-18-14-15-20(23(26)22(18)24-16)21(17-8-4-2-5-9-17)25-19-10-6-3-7-11-19/h2-15,21,25-26H,1H3 |
| InChIKey | WEENRMPCSWFMTE-UHFFFAOYSA-N |
| SafetyPhrases | Classification:Caution–Substancenotyetfullytested.SafetyPhrases:S22-DonotbreathedustS36/37/39-Wearsuitableprotectiveclothing,glovesandeye/faceprotectionS24/25-Avoidcontactwithskinandeyes |
| CiteThisProduct | NSC-66811(StressMarqBiosciencesInc.,VictoriaBCCANADA,Catalog#SIH-338) |
BIOLOGicalDescription
| AlternativeNames | 2-Methyl-7-[Phenyl(phenylamino)methyl]-8-quinolinol,7-[Anilino(phenyl)methyl]-2-methylquinolin-8-ol |
| ResearchAreas | Cancer,Apoptosis,CancerGrowthInhibitors,p53/mdm2Inhibitors |
| PubChemID | 248986 |
| ScientificBackground | AnovelinhibitoroftheMDM2-p53interaction.Mimicsthreep53residuesinvolvedinbindingtoMDM2.BindstoMDM2withaKiof120nM.Activatesp53incancercells.Cellpermeable. |
| References | 1.LuY.,etal.(2006)J.Med.Chem.49:3759. |
ProductImages
ChemicalstructureofNSC-66811(SIH-338),ap53/mdm2inhibitor.CAS#:6964-62-1.MolecularFormula:C23H20N2O.MolecularWeight:340.4g/mol.
ProductCitations(0)
Currentlytherearenocitationsforthisproduct.
品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究，同时在其他领域也取得了一定成就，包括翻译后修饰，提供甲基化与乙酰基化抗体。其中，细胞应激领域主要包括热休克蛋白（HSP）领域。我们公司不仅在热休克蛋白领域领先全球，而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列，分别涉及抗体、蛋白、酶联免疫吸附试验（ELISA）试剂盒及小分子领域。
