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当前位置: 首页 > 产品中心 > acid_base_buffer_solution > StressMarq/Anti-Nrf2 Antibody/SPC-218A-A390/50-µg
商品详细StressMarq/Anti-Nrf2 Antibody/SPC-218A-A390/50-µg
StressMarq/Anti-Nrf2 Antibody/SPC-218A-A390/50-µg
StressMarq/Anti-Nrf2 Antibody/SPC-218A-A390/50-µg
商品编号: SPC-218A-A390
市场价: ¥6660.00
美元价: 3996.00
产地: 美国(厂家直采)
公司:
产品分类: 酸碱缓冲液
公司分类: acid_base_buffer_solution
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

Overview:

Product Name Nrf2 Antibody
Description

Goat Anti-Human Nrf2 Polyclonal

Species Reactivity Dog, Human, Mouse, Rat, Bovine, Pig
Applications WB, ELISA
Antibody Dilution WB (1:1500), ELISA (1:64000); optimal dilutions for assays should be determined by the user.
Host Species Goat
Immunogen Species Human
Immunogen Peptide derived from human Nrf2 protein (a.a. 445-458)
Conjugates Alkaline Phosphatase, APC, ATTO 390, ATTO 488, ATTO 565, ATTO 594, ATTO 633, ATTO 655, ATTO 680, ATTO 700, Biotin, FITC, HRP, PE/ATTO 594, PerCP, RPE, Streptavidin, Unconjugated

Properties

Storage Buffer TBS pH7.3, 0.02% sodium azide, 0.5% BSA
Storage Temperature 4ºC
Shipping Temperature Blue Ice or 4ºC
Purification Protein A purified
Clonality Polyclonal
Specificity Aggrephagy associated oxidative stress response transcription factor.
Cite This Product StressMarq Biosciences Cat# SPC-218, RRID: AB_2704433
Certificate of Analysis A 1:1500 dilution of SPC-218 was sufficient for detection of Nrf2 in 35 µg of human lung lysate by electrochemiluminescence analysis using donkey anti-goat IgG:HRP as the secondary antibody.

Biological Description

Alternative Names Erythroid derived 2 antibody, HEBP1 antibody, like 2 antibody, NF E2 related factor 2 antibody, NF-E2-related factor 2 antibody, NF2L2_HUMAN antibody, NFE2 related factor 2 antibody, NFE2-related factor 2 antibody, NFE2L2 antibody, Nrf 2 antibody, NRF2 antibody, Nuclear factor (erythroid derived 2) like 2 antibody, Nuclear factor antibody, nuclear factor erythroid 2 like 2 antibody, Nuclear factor erythroid 2 related factor 2 antibody, Nuclear factor erythroid 2-related factor 2 antibody, Nuclear factor erythroid derived 2 like 2 antibody
Research Areas Cancer, Cardiovascular System, Cell Signaling, Epigenetics and Nuclear Signaling, Heart, Oxidative Stress
Cellular Localization Cytoplasm, Nucleus
Accession Number NP_006155.2
Gene ID 4780
Swiss Prot Q16236
Scientific Background Nrf2 is a transcription factor which plays a role in the oxidative stress response. Under normal cellular conditions, it is sequestered in the cytoplasm by Keap1 and Cullin3. When under oxidative stress, Nrf2 is release from Keap1 by p62 and is translocated to the nucleus where it acts as a transcription factor for the expression of oxidative stress-related products.
References 1. Itoh K., Wakabayashi N., Katoh Y., Ishii T., Igarashi K., Engel J., et al. (1999) Genes Dev. 13(1): 76-86.

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  ATTO 390
Overview:

  • High fluorescence yield
  • Large Stokes-shift (89 nm)
  • Good photostability
  • Moderately hydrophilic
  • Good solubility in polar solvents
  • Coumarin derivate, uncharged
  • Low molar mass: 343.42 g/mol 

ATTO 390 Datasheet

ATTO 390 Fluorescent Dye Excitation and Emission SpectraOptical Properties:

λex = 390 nm

λem = 479 nm

εmax = 2.4×104

Φf = 0.90

τfl = 5.0 ns

Brightness = 21.6

Laser = 365 or 405 nm

 

品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究,同时在其他领域也取得了一定成就,包括翻译后修饰,提供甲基化与乙酰基化抗体。其中,细胞应激领域主要包括热休克蛋白(HSP)领域。我们公司不仅在热休克蛋白领域领先全球,而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列,分别涉及抗体、蛋白、酶联免疫吸附试验(ELISA)试剂盒及小分子领域。