StressMarq/Nocodazole/SIH-367-50MG/50-mg
商品编号：
SIH-367-50MG
市场价：
¥6160.00
美元价：
3696.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Overview:
| Product Name | Nocodazole |
| Description | Microtubule inhibitor |
| Purity | >98% (HPLC); NMR (conforms) |
| CAS No. | 31430-18-9 |
| Molecular Formula | C14H11N3O3S |
| Molecular Weight | 301.3 |
Properties
| Storage Temperature | -20ºC |
| Shipping Temperature | Shipped Ambient |
| Product Type | Inhibitor |
| Solubility | May be dissolved in DMSO (10 mg/ml, warm) |
| Source | Synthetic |
| Appearance | White to off-white powder. |
| SMILES | COC(=O)NC1=NC2=C(N1)C=CC(=C2)C(=O)C3=CC=CS3 |
| InChI | InChI=1S/C14H11N3O3S/c1-20-14(19)17-13-15-9-5-4-8(7-10(9)16-13)12(18)11-3-2-6-21-11/h2-7H,1H3,(H2,15,16,17,19) |
| InChIKey | KYRVNWMVYQXFEU-UHFFFAOYSA-N |
| Safety Phrases | Classification: Caution: Substance not yet fully tested. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection Hazard Phrases: H341- Suspected of causing genetic defects. H361d – Suspected of damaging the unborn child Precautionary Phrases: P281 – Use personal protective equipment as required. |
| Cite This Product | Nocodazole (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-367) |
Biological Description
| Alternative Names | Methyl (5-[2-thienylcarbonyl]-1H-benzimidazol-2-yl |
| Research Areas | Cancer, Apoptosis, Neuroscience |
| PubChem ID | 4122 |
| Scientific Background | Nocodazole also known as Oncodazole. It is an antimitotic agent, associated with the activity of depolymerization of the microtubules (1). Nocadozole has high affinity with Tubulin but little is known on the mechanism of binding. Studies have shown that Nocadozole binds differently to the various α/β isotypes of Tubulin. By measuring the dissociation constants, with the given binding sites, a novel approach of therapeutic agents is under study (2). |
| References |
1. Vasquez RJ., Howell B., Yvon AM., Wadsworth P., Cassimus L. (1997) Mol Biol Cell. 8(6): 973-985. 2. Kelian Xu., Schwarz P,. Luduena R,. (2002) Drug Drug Dev.Re. 55: 91-96. |
Product Images
Chemical structure of Nocodazole (SIH-367), a Microtubule inhibitor. CAS #: 31430-18-9. Molecular Formula: C14H11N3O3S. Molecular Weight: 301.3 g/mol.
Product Citations (0)
Currently there are no citations for this product.
品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究，同时在其他领域也取得了一定成就，包括翻译后修饰，提供甲基化与乙酰基化抗体。其中，细胞应激领域主要包括热休克蛋白（HSP）领域。我们公司不仅在热休克蛋白领域领先全球，而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列，分别涉及抗体、蛋白、酶联免疫吸附试验（ELISA）试剂盒及小分子领域。
