StressMarq/Nocodazole/SIH-367-10MG/10-mg
商品编号：
SIH-367-10MG
市场价：
¥1620.00
美元价：
972.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Overview:
| ProductName | Nocodazole |
| Description | Microtubuleinhibitor |
| Purity | >98%(HPLC);NMR(conforms) |
| CASNo. | 31430-18-9 |
| MolecularFormula | C14H11N3O3S |
| MolecularWeight | 301.3 |
Properties
| StorageTemperature | -20ºC |
| ShippingTemperature | ShippedAmbient |
| ProductType | Inhibitor |
| Solubility | MaybedissolvedinDMSO(10mg/ml,warm) |
| Source | Synthetic |
| Appearance | Whitetooff-whitepowder. |
| SMILES | COC(=O)NC1=NC2=C(N1)C=CC(=C2)C(=O)C3=CC=CS3 |
| InChI | InChI=1S/C14H11N3O3S/c1-20-14(19)17-13-15-9-5-4-8(7-10(9)16-13)12(18)11-3-2-6-21-11/h2-7H,1H3,(H2,15,16,17,19) |
| InChIKey | KYRVNWMVYQXFEU-UHFFFAOYSA-N |
| SafetyPhrases | Classification:Caution:Substancenotyetfullytested.SafetyPhrases:S22-DonotbreathedustS24/25-AvoidcontactwithskinandeyesS36/37/39-Wearsuitableprotectiveclothing,glovesandeye/faceprotectionHazardPhrases:H341-SUSPectedofcausinggeneticdefects.H361d–SuspectedofdamagingtheunbornchildPrecautionaryPhrases:P281–Usepersonalprotectiveequipmentasrequired. |
| CiteThisProduct | Nocodazole(StressMarqBiosciencesInc.,VictoriaBCCANADA,Catalog#SIH-367) |
BIOLOGicalDescription
| AlternativeNames | Methyl(5-[2-thienylcarbonyl]-1H-benzimidazol-2-yl |
| ResearchAreas | Cancer,Apoptosis,Neuroscience |
| PubChemID | 4122 |
| ScientificBackground | NocodazolealsoknownasOncodazole.Itisanantimitoticagent,associatedwiththeactivityofdepolymerizationofthemicrotubules(1).NocadozolehashighaffinitywithTubulinbutlittleisknownonthemechanismofbinding.StudieshaveshownthatNocadozolebindsdifferentlytothevariousα/βisotypesofTubulin.Bymeasuringthedissociationconstants,withthegivenbindingsites,anovelapproachoftherapeuticagentsisunderstudy(2). |
| References | 1.VasquezRJ.,HowellB.,YvonAM.,WadsworthP.,CassimusL.(1997)MolBiolCell.8(6):973-985. 2.KelianXu.,SchwarzP,.LuduenaR,.(2002)DrugDrugDev.Re.55:91-96. |
ProductImages
ChemicalstructureofNocodazole(SIH-367),aMicrotubuleinhibitor.CAS#:31430-18-9.MolecularFormula:C14H11N3O3S.MolecularWeight:301.3g/mol.
ProductCitations(0)
Currentlytherearenocitationsforthisproduct.
品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究，同时在其他领域也取得了一定成就，包括翻译后修饰，提供甲基化与乙酰基化抗体。其中，细胞应激领域主要包括热休克蛋白（HSP）领域。我们公司不仅在热休克蛋白领域领先全球，而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列，分别涉及抗体、蛋白、酶联免疫吸附试验（ELISA）试剂盒及小分子领域。
