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当前位置: 首页 > 产品中心 > acid_base_buffer_solution > STRESTMARQ/抗NDR1抗体(pSer281+pThr282)/SPC-1035D-A565/100-µl
商品详细STRESTMARQ/抗NDR1抗体(pSer281+pThr282)/SPC-1035D-A565/100-µl
STRESTMARQ/抗NDR1抗体(pSer281+pThr282)/SPC-1035D-A565/100-µl
STRESTMARQ/抗NDR1抗体(pSer281+pThr282)/SPC-1035D-A565/100-µl
商品编号: SPC-1035D-A565
市场价: ¥6840.00
美元价: 4104.00
产地: 美国(厂家直采)
公司:
产品分类: 酸碱缓冲液
公司分类: acid_base_buffer_solution
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

Overview:

Product Name NDR1 Antibody (pSer281+pThr282)
Description

Rabbit Anti-Human NDR1 (pSer281+pThr282) Polyclonal

Species Reactivity Human
Applications WB, AM
Antibody Dilution WB (1:250); optimal dilutions for assays should be determined by the user.
Host Species Rabbit
Immunogen Species Human
Immunogen A phospho-specific peptide corresponding to residues surrounding Ser281 and Thr282 of human NDR1 (AA278-285)
Conjugates Alkaline Phosphatase, APC, ATTO 390, ATTO 488, ATTO 565, ATTO 594, ATTO 633, ATTO 655, ATTO 680, ATTO 700, Biotin, FITC, HRP, PE/ATTO 594, PerCP, RPE, Streptavidin, Unconjugated

Properties

Storage Buffer PBS pH7.4, 50% glycerol, 0.025% Thimerosal
Storage Temperature -20ºC
Shipping Temperature Blue Ice or 4ºC
Purification Peptide Affinity Purified
Clonality Polyclonal
Specificity Detects 54.19 kDa.
Cite This Product StressMarq Biosciences Cat# SPC-1035, RRID: AB_2709029
Certificate of Analysis A 1:250 dilution of SPC-1035 was sufficient for detection of NDR1 (pSer281+pThr282) in 10 µg of HeLa cell lysate by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.

Biological Description

Alternative Names NDR 1 antibody, NDR antibody, Ndr Ser/Thr kinase-like protein antibody, NDR1 antibody, NDR1 protein kinase antibody, Nuclear Dbf2 related kinase 1 antibody, Serine/threonine protein kinase 38 antibody, STK 38 antibody, STK38 antibody, STK38_HUMAN antibody
Cellular Localization Cytoplasm, Nucleus
Accession Number NP_009202
Gene ID 11329
Swiss Prot Q15208
Scientific Background STK38 is a negative regulator of MAP3K1/2 signalling. Converts MAP3K2 from its phosphorylated form to its nonphosphorylated form and inhibits autophosphorylation of MAP3K2. The MAPK/ERK pathway has been implicated in oncogenesis as either a promoter or inhibitor depending on the cancer system. Thus, the role of STK38 in cancer is likely highly contextual.

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 ATTO 565
Overview:

  • High fluorescence yield
  • High thermal and photostability
  • Good solubility in polar solvents
  • Excellent solubility in water
  • Very little aggregation
  • Rhodamine dye derivative
  • Molar Mass: 611 g/mol

ATTO 565 Datasheet

 ATTO 565 Fluorophore Excitation and Emission SpectraOptical Properties:

λex = 563 nm

λem = 592 nm

εmax = 1.2×105

Φf = 0.9

τfl = 3.4 n

Brightness = 10

Laser = 532 nm

Filter set = TRITC

 

品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究,同时在其他领域也取得了一定成就,包括翻译后修饰,提供甲基化与乙酰基化抗体。其中,细胞应激领域主要包括热休克蛋白(HSP)领域。我们公司不仅在热休克蛋白领域领先全球,而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列,分别涉及抗体、蛋白、酶联免疫吸附试验(ELISA)试剂盒及小分子领域。