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当前位置: 首页 > 产品中心 > acid_base_buffer_solution > StressMarq/Anti-mTOR Antibody (pSer2448)/SPC-1034D-A565/100-µl
商品详细StressMarq/Anti-mTOR Antibody (pSer2448)/SPC-1034D-A565/100-µl
StressMarq/Anti-mTOR Antibody (pSer2448)/SPC-1034D-A565/100-µl
StressMarq/Anti-mTOR Antibody (pSer2448)/SPC-1034D-A565/100-µl
商品编号: SPC-1034D-A565
市场价: ¥6840.00
美元价: 4104.00
产地: 美国(厂家直采)
公司:
产品分类: 酸碱缓冲液
公司分类: acid_base_buffer_solution
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

Overview:

ProductNamemTORAntibody(pSer2448)
Description

RabbitAnti-HumanmTOR(pSer2448)Polyclonal

SpeciesReactivityHuman
ApplicationsWB,AM
AntibodyDilutionWB(1:250);optimaldilutionsforassaysshouldbedeterminedbytheuser.
HostSpeciesRabbit
ImmunogenSpeciesHuman
ImmunogenAphospho-specificpeptidecorrespondingtoresiduessurroundingSer2448ofhumanmTOR(AA2445-2451)
ConjugatesAlkalinePhosphatase,APC,ATTO390,ATTO488,ATTO565,ATTO594,ATTO633,ATTO655,ATTO680,ATTO700,Biotin,FITC,HRP,PE/ATTO594,PerCP,RPE,Streptavidin,Unconjugated

Properties

StorageBufferPBSpH7.4,50%glycerol,0.025%Thimerosal
StorageTemperature-20ºC
ShippingTemperatureBlueIceor4ºC
PurificationPeptideAffinityPurified
ClonalityPolyclonal
SpecificityDetects288.892kDa.
CiteThisProductStressMarqBiosciencesCat#SPC-1034,RRID:AB_2709011
CertificateofAnalysisA1:250dilutionofSPC-1034wassufficientfordetectionofmTOR(pSer2448)in10µgofHeLacelllysatebyECLimmunoblotanalysisusinggoatanti-rabbitIgG:HRPasthesecondaryantibody.

BIOLOGicalDescription

AlternativeNamesFK506bindingprotein12rapamycinassociatedprotein1antibody,FK506bindingprotein12rapamycinassociatedprotein2antibody,FKBPrapamycinassociatedproteinantibody,FKBP12rapamycincomplexassociatedproteinantibody,FRAPantibody,FRAP1antibody,FRAP2antibody,Mammaliantargetofrapamycinantibody,MechaNISTictargetofrapamycinantibody,mTORantibody,MTOR_HUMANantibody,RAFT1antibody,RapamycinandFKBP12target1antibody,Rapamycintargetprotein1antibody,Rapamycintargetproteinantibody,RAPT1antibody,Serine/threonine-proteinkinasemTORantibody
CellularLocalizationCytoplasm,Endoplasmicreticulummembrane,GolgiApparatusMembrane,Lysosome
AccessionNumberNP_004949
GeneID2475
SwissProtP42345
ScientificBackgroundMTORisaprotein-serine/threoninekinase.Itregulatesvariouscellularpathwayssuchasinsulinsignalling,eIF4eandp70S6kinaseactivationforproteinsynthesis,HIFa,VEGF,cellproliferation,nutrientandhormonesignals,ribosomebiogenesis,regulationofcellcycleprogrssion,angiogensis,cellpolarityandcytokeletonreorganization.DysregulationinsignallingthatleadstoconstantactivationofmTORleadtouncontrolledprolifertaionandcellcycleprogressionandoncogensis.IncreasedinvasivenesshasalsobeshowndobeassociatedwithmTORactivity.Whileitfeaturesawiderangeofmutations,thismightreflecttheverylargesizeoftheproteinratherthanitsidentificationasatumoursuppressorprotein.

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 ATTO565
Overview:
  • Highfluorescenceyield
  • HighthermalandphotostABIlity
  • Goodsolubilityinpolarsolvents
  • Excellentsolubilityinwater
  • Verylittleaggregation
  • Rhodaminedyederivative
  • MolarMass:611g/mol

ATTO565Datasheet

 ATTO 565 Fluorophore Excitation and Emission SpectraOpticalProperties:

λex =563nm

λem=592nm

εmax=1.2×105

Φf= 0.9

τfl =3.4n

Brightness=10

Laser =532nm

Filterset = TRITC

 

品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究,同时在其他领域也取得了一定成就,包括翻译后修饰,提供甲基化与乙酰基化抗体。其中,细胞应激领域主要包括热休克蛋白(HSP)领域。我们公司不仅在热休克蛋白领域领先全球,而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列,分别涉及抗体、蛋白、酶联免疫吸附试验(ELISA)试剂盒及小分子领域。