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当前位置: 首页 > 产品中心 > acid_base_buffer_solution > STRESS MARQ/MS 275/SIH-416-1MG/1-mg
商品详细STRESS MARQ/MS 275/SIH-416-1MG/1-mg
STRESS MARQ/MS 275/SIH-416-1MG/1-mg
STRESS MARQ/MS 275/SIH-416-1MG/1-mg
商品编号: SIH-416-1MG
市场价: ¥1900.00
美元价: 1140.00
产地: 美国(厂家直采)
公司:
产品分类: 酸碱缓冲液
公司分类: acid_base_buffer_solution
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

Overview:

ProductNameMS275
Description

HDACinhibitor

Purity>98.5
CASNo.209783-80-2
MolecularFormulaC21H20N4O3
MolecularWeight376.41

Properties

StorageTemperature-20ºC
ShippingTemperatureShippedAmbient
ProductTypeInhibitor
SolubilitySolubleinDMSOormethanol.
SourceSynthetic
AppearanceOffwhitesolid
SMILESC2=C(C(=O)NC1=C(N)C=CC=C1)C=CC(=C2)CNC(OCC3=CN=CC=C3)=O
InChIInChI=1S/C21H20N4O3/c22-18-5-1-2-6-19(18)25-20(26)17-9-7-15(8-10-17)13-24-21(27)28-14-16-4-3-11-23-12-16/h1-12H,13-14,22H2,(H,24,27)(H,25,26)
InChIKeyINVTYAOGFAGBOE-UHFFFAOYSA-N
SafetyPhrasesClassification:D1BToxicMaterialCausingImmediateandSeriousToxicEffects,Toxicbyingestion,D2AVeryToxicMaterialCausingOtherToxicEffects,Teratogen,D2BToxicMaterialCausingOtherToxicEffects,Reproductivehazard,Moderateskinirritant,ModerateeyeirritantSafetyPhrases:S22-Donotbreathedust.S24/25-Avoidcontactwithskinandeyes.S36/37/39-Wearsuitableprotectiveclothing,glovesandeye/faceprotection.Hazardstatements:H301Toxicifswallowed.H315Causesskinirritation.H319Causesseriouseyeirritation.H335Maycauserespiratoryirritation.H360Maydamagefertilityortheunbornchild.Precautionarystatements:P201Obtainspecialinstructionsbeforeuse.P261Avoidbreathingdust/fume/gas/mist/vapours/spray.P301+P310IFSWALLOWED:ImmediatelycallaPOISONCENTERordoctor/physician.P305+P351+P338IFINEYES:Rinsecautiouslywithwaterforseveralminutes.Removecontactlenses,ifpresentandeasytodo.Continuerinsing.P308+P313IFexposedorconcerned:Getmedicaladvice/attention.
CiteThisProductMS275(StressMarqBiosciencesInc.,VictoriaBCCANADA,Catalog#SIH-416)

BIOLOGicalDescription

AlternativeNames3-pyridinylmethyl[[4-[[(2-aminophenyl)amino]carbonyl]phenyl]methyl]carbamate,N-(2-Aminophenyl)-4-[N-(pyridine-3ylmethoxycarbonyl)aminomethyl]benzamide
ResearchAreasCancer,CellSignaling,Epigenetics
PubChemID4261
ScientificBackgroundMS275,alsoreferredtoasEntinostat,isabenzamidehistonedeacetylaseinhibitor.ItpreferentiallyinhibitsHDAC1andHDAC3.ItiscurrentlyundergoingseveralclinicaltrialsforthetreatmentofHodgkin"slymphoma,advancedbreastcancer,andformetastaticlungcancer.
References1.CamphausenK.,BurganW.,CerraM.,OswaldK.A.,TrepelJ.B.,LeeM.J.,etal.(2004)CancerRes.316-21.

ProductImages

<p>Chemical structure of MS 275 (SIH-416), a HDAC inhibitor. CAS #: 209783-80-2. Molecular Formula: C21H20N4O3. Molecular Weight: 376.41 g/mol.</p>

ChemicalstructureofMS275(SIH-416),aHDACinhibitor.CAS#:209783-80-2.MolecularFormula:C21H20N4O3.MolecularWeight:376.41g/mol.

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品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究,同时在其他领域也取得了一定成就,包括翻译后修饰,提供甲基化与乙酰基化抗体。其中,细胞应激领域主要包括热休克蛋白(HSP)领域。我们公司不仅在热休克蛋白领域领先全球,而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列,分别涉及抗体、蛋白、酶联免疫吸附试验(ELISA)试剂盒及小分子领域。