StressMarq/Midostaurin/SIH-468-5MG/5-mg
商品编号：
SIH-468-5MG
市场价：
¥7900.00
美元价：
4740.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Overview:
| ProductName | Midostaurin |
| Description | Kinaseinhibitor |
| Purity | >98%(TLC) |
| CASNo. | 120685-11-2 |
| MolecularFormula | C35H30N4O4 |
| MolecularWeight | 570.6 |
Properties
| StorageTemperature | -20ºC |
| ShippingTemperature | ShippedAmbient |
| ProductType | Inhibitor |
| Solubility | SolubleinDMSO(15mg/ml),MDC(10mg/ml),methanol(5mg/ml)or100%ethanol(2.5mg/ml) |
| Source | Synthetic |
| Appearance | Whitetooff-whitepowder |
| SMILES | [N]48C1=C(C7=C(C2=C1[N](C3=CC=CC=C23)[[email protected]@H]5O[[email protected]]4([[email protected]@]([[email protected]@H]5N(C)C(=O)C6=CC=CC=C6)(OC)C)C)C(NC7)=O)C9=C8C=CC=C9 |
| InChI | InChI=1S/C35H30N4O4/c1-35-32(42-3)25(37(2)34(41)19-11-5-4-6-12-19)17-26(43-35)38-23-15-9-7-13-20(23)28-29-22(18-36-33(29)40)27-21-14-8-10-16-24(21)39(35)31(27)30(28)38/h4-16,25-26,32H,17-18H2,1-3H3,( |
| InChIKey | BMGQWWVMWDBQGC-PZFYLCKJSA-N |
| SafetyPhrases | Classification:Notahazardoussubstanceormixture.SafetyPhrases:S22-Donotbreathedust.S24/25-Avoidcontactwithskinandeyes.S36/37/39-Wearsuitableprotectiveclothing,glovesandeye/faceprotection. |
| CiteThisProduct | Midostaurin(StressMarqBiosciencesInc.,VictoriaBCCANADA,Catalog#SIH-468) |
BIOLOGicalDescription
| AlternativeNames | 4’-N-Benzoyl-staurosporine,PKC-412,CGP41251 |
| ResearchAreas | Cancer,Apoptosis,CancerGrowthInhibitors,CellSignaling,TyrosineKinaseInhibitors |
| PubChemID | 24202429 |
| ScientificBackground | Midostaurinisabroadspectrumproteinkinaseinhibitor.ItalsoshowsinhibitionofPKCα,PKCβandPKCγisoforms,Flk,andc-kit.MidostaurindisplaysantiproliferativecharacteristicsandtheABIlitytoinduceapoptosis. |
| References | 1.FabbroD.,etal.(2000)Anti-CancerDrugDesign.15(1):17–28. 2.Odgerel,T.,etal.(2008)Oncogene.27(22):3102–3110. 3.Bahlis,N.J.,etal.(2005)Leukemia&Lymphoma.46(6):899–908. |
ProductImages
ChemicalstructureofMidostaurin(SIH-468),aProteinkinaseinhibitor(panspec.).CAS#:120685-11-2.MolecularFormula:C35H30N4O4.MolecularWeight:570.6g/mol.
ProductCitations(0)
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品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究，同时在其他领域也取得了一定成就，包括翻译后修饰，提供甲基化与乙酰基化抗体。其中，细胞应激领域主要包括热休克蛋白（HSP）领域。我们公司不仅在热休克蛋白领域领先全球，而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列，分别涉及抗体、蛋白、酶联免疫吸附试验（ELISA）试剂盒及小分子领域。
