StressMarq/MG-132/SIH-326-5MG/5-mg
商品编号：
SIH-326-5MG
市场价：
¥700.00
美元价：
420.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Overview:
| ProductName | MG-132 |
| Description | ProteasomeInhibitor |
| Purity | >98% |
| CASNo. | 133407-82-6 |
| MolecularFormula | C26H41N3O5,C26H41N3O6 |
| MolecularWeight | 475.6,476.6 |
Properties
| StorageTemperature | -20ºC |
| ShippingTemperature | ShippedAmbient |
| ProductType | Inhibitor |
| Solubility | Solublein45mg/mlDMSO,DMFandethanol |
| Source | Synthetic |
| Appearance | Whitesolid |
| SMILES | CC(C)C[[email protected]@H](C=O)NC(=O)[[email protected]](CC(C)C)NC(=O)[[email protected]](CC(C)C)NC(=O)OCC1=CC=CC=C1 |
| InChI | InChI=1S/C26H41N3O5/c1-17(2)12-21(15-30)27-24(31)22(13-18(3)4)28-25(32)23(14-19(5)6)29-26(33)34-16-20-10-8-7-9-11-20/h7-11,15,17-19,21-23H,12-14,16H2,1-6H3,(H,27,31)(H,28,32)(H,29,33)/t21-,22-,23-/m0 |
| InChIKey | TZYWCYJVHRLUCT-VABKMULXSA-N |
| SafetyPhrases | Classification:Caution:Substancenotyetfullytested.SafetyPhrases:S36/37/39-Wearsuitableprotectiveclothing,glovesandeye/faceprotectionS24/25-Avoidcontactwithskinandeyes |
| CiteThisProduct | MG-132(StressMarqBiosciencesInc.,VictoriaBCCANADA,Catalog#SIH-326) |
BIOLOGicalDescription
| AlternativeNames | N-[(Benzyloxy)carbonyl]-L-leucyl-N-[(2S)-4-methyl-1-oxo-2-pentanyl]-L-leucinamide,Z-Leu-Leu-Leu-al,Z-LLL-CHO,N-[(phenylmethoxy)carbonyl]-L-leucyl-N-[(1S)-1-formyl-3-methylbutyl]-L-leucinamide |
| ResearchAreas | Cancer,HeatShock |
| PubChemID | 462382 |
| ScientificBackground | Specificinhibitorofthe20Sproteasome(Ki=4nM).BlocksNFKBactivationbyblockingIKBproteolysis(IC50=3M).Itstimulatesautophagy,inducesheatshockresponseandiscellpermeable |
| References | 1. TsubukiS.,etal.(1996)J.Biochem.119:572. 2.WuW.K.,etal.(2010)Autophagy6:228. 3.MeriinA.B.,etal.(1998)J.Biol.Chem.273:6373. |
ProductImages
ChemicalstructureofMG-132(SIH-326),aProteasomeInhibitor.CAS#:133407-82-6.MolecularFormula:C26H41N3O6.MolecularWeight:476.6g/mol.
ProductCitations(0)
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品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究，同时在其他领域也取得了一定成就，包括翻译后修饰，提供甲基化与乙酰基化抗体。其中，细胞应激领域主要包括热休克蛋白（HSP）领域。我们公司不仅在热休克蛋白领域领先全球，而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列，分别涉及抗体、蛋白、酶联免疫吸附试验（ELISA）试剂盒及小分子领域。
