STRESS MARQ/盐酸二甲双胍/SIH-395-5G/5-g
商品编号：
SIH-395-5G
市场价：
¥780.00
美元价：
468.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Overview:
| ProductName | MetforminHydrochloride |
| Description | Autophagyinducer |
| Purity | >97% |
| CASNo. | 1115-70-4 |
| MolecularFormula | C4H11N5•HCl |
| MolecularWeight | 165.6 |
Properties
| StorageTemperature | -20ºC |
| ShippingTemperature | ShippedAmbient |
| ProductType | Inducer |
| Solubility | Solubleto100mMinwaterandto50mMinDMSO. |
| Source | Synthetic |
| Appearance | Whitecrystallinepowder. |
| SMILES | [H+].CN(C)C(N=C(N)N)=N.[Cl-] |
| InChI | InChI=1S/C4H11N5.ClH/c1-9(2)4(7)8-3(5)6;/h1-2H3,(H5,5,6,7,8);1H |
| InChIKey | OETHQSJEHLVLGH-UHFFFAOYSA-N |
| SafetyPhrases | Classification:D2B-ToxicMaterialCausingOtherToxicEffects,Moderateskinirritant,ModerateeyeirritantSafetyPhrases:S22-Donotbreathedust.S24/25-Avoidcontactwithskinandeyes.S36/37/39-Wearsuitableprotectiveclothing,glovesandeye/faceprotection.Hazardstatements:H302-Harmfulifswallowed.H315-Causesskinirritation.H319-Causesseriouseyeirritation.Precautionarystatements:P305+P351+P338-IFINEYES:Rinsecautiouslywithwaterforseveralminutes.Removecontactlenses,ifpresentandeasytodo.Continuerinsing. |
| CiteThisProduct | MetforminHydrochloride(StressMarqBiosciencesInc.,VictoriaBCCANADA,Catalog#SIH-395) |
BIOLOGicalDescription
| AlternativeNames | N,N-Dimethylimidodicarbonimidicdiamidehydrochloride |
| ResearchAreas | Cancer,Autophagy |
| PubChemID | 14219 |
| ScientificBackground | MetforminHydrochlorideisanantidiabeticagentwhichreducesblood-glucoselevelsaswellasimprovesinsulinsensitivity.MetforminhasalsobeenshowntoinhibithepaticgluconeogenesisviaactivationofLKB1-AMPK(AMP-activatedproteinkinase)pathway.Theactivationofthispathwayhasalsobeenseentohaveanantiproliferativeandpro-apoptoticeffectincancercells.Lastly,MetforminisbelievedtoinduceautophagythroughinhibitionofthemTORC1pathway. |
| References | 1.KirpichnikovD.,etal.(2002).AnnInternMed.137(1):25-33. 2.CatonP.W.,etal.(2010).JEndocrino;.205(1):97-106. 3.FengY.H.,etal.(2011).JCellMolMed.15(4):825-36. 4.HuangH.,etal.(2013).Autophagy.9(2):175-95. |
ProductImages
ChemicalstructureofMetforminHydrochloride(SIH-395),aAutophagyinducer.CAS#:1115-70-4.MolecularFormula:C4H11N5.HCl.MolecularWeight:165.6g/mol.
ProductCitations(0)
Currentlytherearenocitationsforthisproduct.
品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究，同时在其他领域也取得了一定成就，包括翻译后修饰，提供甲基化与乙酰基化抗体。其中，细胞应激领域主要包括热休克蛋白（HSP）领域。我们公司不仅在热休克蛋白领域领先全球，而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列，分别涉及抗体、蛋白、酶联免疫吸附试验（ELISA）试剂盒及小分子领域。
