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当前位置: 首页 > 产品中心 > acid_base_buffer_solution > STRESS MARQ/盐酸二甲双胍/SIH-395-5G/5-g
商品详细STRESS MARQ/盐酸二甲双胍/SIH-395-5G/5-g
STRESS MARQ/盐酸二甲双胍/SIH-395-5G/5-g
STRESS MARQ/盐酸二甲双胍/SIH-395-5G/5-g
商品编号: SIH-395-5G
市场价: ¥780.00
美元价: 468.00
产地: 美国(厂家直采)
公司:
产品分类: 酸碱缓冲液
公司分类: acid_base_buffer_solution
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

Overview:

ProductNameMetforminHydrochloride
Description

Autophagyinducer

Purity>97%
CASNo.1115-70-4
MolecularFormulaC4H11N5•HCl
MolecularWeight165.6

Properties

StorageTemperature-20ºC
ShippingTemperatureShippedAmbient
ProductTypeInducer
SolubilitySolubleto100mMinwaterandto50mMinDMSO.
SourceSynthetic
AppearanceWhitecrystallinepowder.
SMILES[H+].CN(C)C(N=C(N)N)=N.[Cl-]
InChIInChI=1S/C4H11N5.ClH/c1-9(2)4(7)8-3(5)6;/h1-2H3,(H5,5,6,7,8);1H
InChIKeyOETHQSJEHLVLGH-UHFFFAOYSA-N
SafetyPhrasesClassification:D2B-ToxicMaterialCausingOtherToxicEffects,Moderateskinirritant,ModerateeyeirritantSafetyPhrases:S22-Donotbreathedust.S24/25-Avoidcontactwithskinandeyes.S36/37/39-Wearsuitableprotectiveclothing,glovesandeye/faceprotection.Hazardstatements:H302-Harmfulifswallowed.H315-Causesskinirritation.H319-Causesseriouseyeirritation.Precautionarystatements:P305+P351+P338-IFINEYES:Rinsecautiouslywithwaterforseveralminutes.Removecontactlenses,ifpresentandeasytodo.Continuerinsing.
CiteThisProductMetforminHydrochloride(StressMarqBiosciencesInc.,VictoriaBCCANADA,Catalog#SIH-395)

BIOLOGicalDescription

AlternativeNamesN,N-Dimethylimidodicarbonimidicdiamidehydrochloride
ResearchAreasCancer,Autophagy
PubChemID14219
ScientificBackgroundMetforminHydrochlorideisanantidiabeticagentwhichreducesblood-glucoselevelsaswellasimprovesinsulinsensitivity.MetforminhasalsobeenshowntoinhibithepaticgluconeogenesisviaactivationofLKB1-AMPK(AMP-activatedproteinkinase)pathway.Theactivationofthispathwayhasalsobeenseentohaveanantiproliferativeandpro-apoptoticeffectincancercells.Lastly,MetforminisbelievedtoinduceautophagythroughinhibitionofthemTORC1pathway.
References1.KirpichnikovD.,etal.(2002).AnnInternMed.137(1):25-33.
2.CatonP.W.,etal.(2010).JEndocrino;.205(1):97-106.
3.FengY.H.,etal.(2011).JCellMolMed.15(4):825-36.
4.HuangH.,etal.(2013).Autophagy.9(2):175-95.

ProductImages

<p>Chemical structure of Metformin Hydrochloride (SIH-395), a Autophagy inducer. CAS #: 1115-70-4. Molecular Formula: C4H11N5 . HCl. Molecular Weight: 165.6 g/mol.</p>

ChemicalstructureofMetforminHydrochloride(SIH-395),aAutophagyinducer.CAS#:1115-70-4.MolecularFormula:C4H11N5.HCl.MolecularWeight:165.6g/mol.

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品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究,同时在其他领域也取得了一定成就,包括翻译后修饰,提供甲基化与乙酰基化抗体。其中,细胞应激领域主要包括热休克蛋白(HSP)领域。我们公司不仅在热休克蛋白领域领先全球,而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列,分别涉及抗体、蛋白、酶联免疫吸附试验(ELISA)试剂盒及小分子领域。