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当前位置: 首页 > 产品中心 > acid_base_buffer_solution > StressMarq/Anti-MCL1 Antibody/SPC-1328D-A594/100-µl
商品详细StressMarq/Anti-MCL1 Antibody/SPC-1328D-A594/100-µl
StressMarq/Anti-MCL1 Antibody/SPC-1328D-A594/100-µl
StressMarq/Anti-MCL1 Antibody/SPC-1328D-A594/100-µl
商品编号: SPC-1328D-A594
市场价: ¥6040.00
美元价: 3624.00
产地: 美国(厂家直采)
公司:
产品分类: 酸碱缓冲液
公司分类: acid_base_buffer_solution
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

Overview:

ProductNameMCL1Antibody
Description

RabbitAnti-HumanMCL1Polyclonal

SpeciesReactivityHuman,Mouse,Rat
ApplicationsWB,IHC,ELISA
AntibodyDilutionWB(1:1000),IHC(1:100),ELISA(1:40000);optimaldilutionsforassaysshouldbedeterminedbytheuser.
HostSpeciesRabbit
ImmunogenSpeciesHuman
ImmunogenSynthesizedpeptidederivedfromhumanMCL1.
ConjugatesAlkalinePhosphatase,APC,ATTO390,ATTO488,ATTO565,ATTO594,ATTO633,ATTO655,ATTO680,ATTO700,Biotin,FITC,HRP,PE/ATTO594,PerCP,RPE,Streptavidin,Unconjugated

Properties

StorageBufferPBSpH7.4,50%glycerol,150mMNaCl,0.02%sodiumazide
StorageTemperature-20ºC
ShippingTemperatureBlueIceor4ºC
PurificationAffinityPurified
ClonalityPolyclonal
IsotypeIgG
SpecificityDetectsendogenouslevelsoftotalMCL1protein.
CiteThisProductStressMarqBiosciencesCat#SPC-1328,RRID:AB_2713691
CertificateofAnalysisA1:1000dilutionofSPC-1328wassufficientfordetectionofMCL1in10µgofHuvEccelllysatesbyECLimmunoblotanalysisusingGoatAnti-RabbitIgG:HRPasthesecondaryantibody.

BIOLOGicalDescription

AlternativeNamesBcl2relatedproteinEAT/mcl1antibody,Bcl-2-likeprotein3antibody,Bcl-2-relatedproteinEAT/mcl1antibody,BCL2relatedantibody,Bcl2-L-3antibody,BCL2L3antibody,EATantibody,InducedmyeloidleukemiacelldifferentiationproteinMcl1antibody,InducedmyeloidleukemiacelldifferentiationproteinMcl-1antibody,MCL1antibody,MCL1antibody,MCL1-ESantibody,mcl1/EATantibody,MCL1_HUMANantibody,MCL1Lantibody,MCL1Santibody,MGC104264antibody,MGC1839antibody,MyeloidCellLeukemia1antibody,MyeloidcellleukemiaESantibody,Myeloidcellleukemiasequence1antibody,Myeloidcellleukemiasequence1BCL2relatedantibody,Myeloidcellleukemiasequence1isoform1antibody,OTTHUMP00000032794antibody,OTTHUMP00000032795antibody,TMantibody
CellularLocalizationCytoplasm,Membrane,Mitochondrion,Nucleus
AccessionNumberNP_068779.1
GeneID4170
SwissProtQ07820
ScientificBackgroundInducedmyeloidleukemiacelldifferentiationproteinMcl-1isaproteinthatinhumansisencodedbytheMCL1gene.Itisinvolvedintheregulationofapoptosisversuscellsurvival,andinthemaintenanceofviABIlitybutnotofproliferation.Mediatesitseffectsbyinteractionswithanumberofotherregulatorsofapoptosis.Isoform1inhibitsapoptosis.Isoform2promotesapoptosis.
References1.KozopasKM.etal.(1993)ProcNatlAcadSciUSA90(8):3516–20.
2.CraigRW.etal.(1995)Genomics23(2):457–63.

ProductImages

<p>Immunohistochemistry analysis using Rabbit Anti-MCL1 Polyclonal Antibody (SPC-1328). Tissue: Breast Carcinoma Tissue. Species: Human. Fixation: Formalin fixed paraffin-embedded. Primary Antibody: Rabbit Anti-MCL1 Polyclonal Antibody (SPC-1328) at 1:100. The image on the right is treated with the synthesized peptide.</p>

ImmunohistochemistryanalysisusingRabbitAnti-MCL1PolyclonalAntibody(SPC-1328).Tissue:BreastCarcinomaTissue.Species:Human.Fixation:Formalinfixedparaffin-embedded.PrimaryAntibody:RabbitAnti-MCL1PolyclonalAntibody(SPC-1328)at1:100.Theimageontherightistreatedwiththesynthesizedpeptide.

<p>Western blot analysis of Human HuvEc cell lysates showing detection of ~40kDa MCL1 protein using Rabbit Anti-MCL1 Polyclonal Antibody (SPC-1328). Lane 1: Human HuvEc cells. Lane 2: Human HuvEc cells treated with the immunizing peptide. Primary Antibody: Rabbit Anti-MCL1 Polyclonal Antibody (SPC-1328) at 1:1000. Predicted/Observed Size: ~40kDa.</p>

WesternblotanalysisofHumanHuvEccelllysatesshowingdetectionof~40kDaMCL1proteinusingRabbitAnti-MCL1PolyclonalAntibody(SPC-1328).Lane1:HumanHuvEccells.Lane2:HumanHuvEccellstreatedwiththeimmunizingpeptide.PrimaryAntibody:RabbitAnti-MCL1PolyclonalAntibody(SPC-1328)at1:1000.Predicted/ObservedSize:~40kDa.

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 ATTO594
Overview:
  • Highfluorescenceyield
  • Highphotostability
  • Veryhydrophilic
  • Excellentsolubilityinwater
  • Verylittleaggregation
  • Newdyewithnetchargeof-1
  • MolarMass:1137g/mol

ATTO594Datasheet

 ATTO 594 Fluorophore Excitation and Emission SpectrumOpticalProperties:

λex =601 nm

λem=627nm

εmax=1.2×105

Φf= 0.85

τfl =3.5ns

Brightness=102

Laser =594nm

Filterset =TexasRed®

 

品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究,同时在其他领域也取得了一定成就,包括翻译后修饰,提供甲基化与乙酰基化抗体。其中,细胞应激领域主要包括热休克蛋白(HSP)领域。我们公司不仅在热休克蛋白领域领先全球,而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列,分别涉及抗体、蛋白、酶联免疫吸附试验(ELISA)试剂盒及小分子领域。