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当前位置： 首页 > 产品中心 > acid_base_buffer_solution > StressMarq/Anti-MCL1 Antibody/SPC-1328D-A488/100-µl
商品详细StressMarq/Anti-MCL1 Antibody/SPC-1328D-A488/100-µl
StressMarq/Anti-MCL1 Antibody/SPC-1328D-A488/100-µl
StressMarq/Anti-MCL1 Antibody/SPC-1328D-A488/100-µl
商品编号： SPC-1328D-A488
市场价： ¥6040.00
美元价： 3624.00
产地： 美国(厂家直采)
公司：
产品分类： 酸碱缓冲液
公司分类： acid_base_buffer_solution
联系Q Q： 3392242852
电话号码： 4000-520-616
电子邮箱： info@ebiomall.com
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商品介绍

Overview:

Product Name MCL1 Antibody
Description

Rabbit Anti-Human MCL1 Polyclonal

Species Reactivity Human, Mouse, Rat
Applications WB, IHC, ELISA
Antibody Dilution WB (1:1000), IHC (1:100), ELISA (1:40000); optimal dilutions for assays should be determined by the user.
Host Species Rabbit
Immunogen Species Human
Immunogen Synthesized peptide derived from human MCL1.
Conjugates Alkaline Phosphatase, APC, ATTO 390, ATTO 488, ATTO 565, ATTO 594, ATTO 633, ATTO 655, ATTO 680, ATTO 700, Biotin, FITC, HRP, PE/ATTO 594, PerCP, RPE, Streptavidin, Unconjugated

Properties

Storage Buffer PBS pH 7.4, 50% glycerol, 150mM NaCl, 0.02% sodium azide
Storage Temperature -20ºC
Shipping Temperature Blue Ice or 4ºC
Purification Affinity Purified
Clonality Polyclonal
Isotype IgG
Specificity Detects endogenous levels of total MCL1 protein.
Cite This Product StressMarq Biosciences Cat# SPC-1328, RRID: AB_2713691
Certificate of Analysis A 1:1000 dilution of SPC-1328 was sufficient for detection of MCL1 in 10 µg of HuvEc cell lysates by ECL immunoblot analysis using Goat Anti-Rabbit IgG:HRP as the secondary antibody.

Biological Description

Alternative Names Bcl 2 related protein EAT/mcl1 antibody, Bcl-2-like protein 3 antibody, Bcl-2-related protein EAT/mcl1 antibody, BCL2 related antibody, Bcl2-L-3 antibody, BCL2L3 antibody, EAT antibody, Induced myeloid leukemia cell differentiation protein Mcl 1 antibody, Induced myeloid leukemia cell differentiation protein Mcl-1 antibody, MCL 1 antibody, MCL1 antibody, MCL1-ES antibody, mcl1/EAT antibody, MCL1_HUMAN antibody, MCL1L antibody, MCL1S antibody, MGC104264 antibody, MGC1839 antibody, Myeloid Cell Leukemia 1 antibody, Myeloid cell leukemia ES antibody, Myeloid cell leukemia sequence 1 antibody, Myeloid cell leukemia sequence 1 BCL2 related antibody, Myeloid cell leukemia sequence 1 isoform 1 antibody, OTTHUMP00000032794 antibody, OTTHUMP00000032795 antibody, TM antibody
Cellular Localization Cytoplasm, Membrane, Mitochondrion, Nucleus
Accession Number NP_068779.1
Gene ID 4170
Swiss Prot Q07820
Scientific Background Induced myeloid leukemia cell differentiation protein Mcl-1 is a protein that in humans is encoded by the MCL1 gene. It is involved in the regulation of apoptosis versus cell survival, and in the maintenance of viability but not of proliferation. Mediates its effects by interactions with a number of other regulators of apoptosis. Isoform 1 inhibits apoptosis. Isoform 2 promotes apoptosis.
References 1. Kozopas KM. et al. (1993) Proc Natl Acad Sci U S A 90 (8): 3516–20.
2. Craig RW. et al. (1995) Genomics 23 (2): 457–63.

Product Images

<p>Immunohistochemistry analysis using Rabbit Anti-MCL1 Polyclonal Antibody (SPC-1328). Tissue: Breast Carcinoma Tissue. Species: Human. Fixation: Formalin fixed paraffin-embedded. Primary Antibody: Rabbit Anti-MCL1 Polyclonal Antibody (SPC-1328) at 1:100. The image on the right is treated with the synthesized peptide.</p>

Immunohistochemistry analysis using Rabbit Anti-MCL1 Polyclonal Antibody (SPC-1328). Tissue: Breast Carcinoma Tissue. Species: Human. Fixation: Formalin fixed paraffin-embedded. Primary Antibody: Rabbit Anti-MCL1 Polyclonal Antibody (SPC-1328) at 1:100. The image on the right is treated with the synthesized peptide.

<p>Western blot analysis of Human HuvEc cell lysates showing detection of ~40kDa MCL1 protein using Rabbit Anti-MCL1 Polyclonal Antibody (SPC-1328). Lane 1: Human HuvEc cells. Lane 2: Human HuvEc cells treated with the immunizing peptide. Primary Antibody: Rabbit Anti-MCL1 Polyclonal Antibody (SPC-1328) at 1:1000. Predicted/Observed Size: ~40kDa.</p>

Western blot analysis of Human HuvEc cell lysates showing detection of ~40kDa MCL1 protein using Rabbit Anti-MCL1 Polyclonal Antibody (SPC-1328). Lane 1: Human HuvEc cells. Lane 2: Human HuvEc cells treated with the immunizing peptide. Primary Antibody: Rabbit Anti-MCL1 Polyclonal Antibody (SPC-1328) at 1:1000. Predicted/Observed Size: ~40kDa.

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  ATTO 488
Overview:

  • High fluorescence yield
  • High photostability
  • Very hydrophilic
  • Excellent solubility in water
  • Very little aggregation
  • New dye with net charge of -1
  • Molar Mass: 804 g/mol 

ATTO 488 Datasheet

  ATTO 488 Fluorophore Excitation and Emission SpectraOptical Properties:

λex = 501 nm

λem = 523 nm

εmax = 9.0×104

Φf = 0.80

τfl = 4.1 ns

Brightness = 72

Laser = 488 nm

Filter set = FITC

 

品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究，同时在其他领域也取得了一定成就，包括翻译后修饰，提供甲基化与乙酰基化抗体。其中，细胞应激领域主要包括热休克蛋白（HSP）领域。我们公司不仅在热休克蛋白领域领先全球，而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列，分别涉及抗体、蛋白、酶联免疫吸附试验（ELISA）试剂盒及小分子领域。
公司介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究，同时在其他领域也取得了一定成就，包括翻译后修饰，提供甲基化与乙酰基化抗体。其中，细胞应激领域主要包括热休克蛋白（HSP）领域。我们公司不仅在热休克蛋白领域领先全球，而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列，分别涉及抗体、蛋白、酶联免疫吸附试验（ELISA）试剂盒
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