StressMarq/Anti-MAPK4 Antibody (pSer186)/SPC-976D-P594/100-µl-免疫在线蚂蚁淘旗下平台

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商品详细StressMarq/Anti-MAPK4 Antibody (pSer186)/SPC-976D-P594/100-µl

StressMarq/Anti-MAPK4 Antibody (pSer186)/SPC-976D-P594/100-µl

商品编号： SPC-976D-P594

品牌： StressMarq Biosciences

市场价： ¥6980.00

美元价： 4188.00

产地：美国(厂家直采)

公司：

产品分类：酸碱缓冲液

公司分类： acid_base_buffer_solution

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Overview:

Product Name MAPK4 Antibody (pSer186)

Description

Rabbit Anti-Human MAPK4 (pSer186) Polyclonal

Species Reactivity Human

Applications WB, AM

Antibody Dilution WB (1:250); optimal dilutions for assays should be determined by the user.

Host Species Rabbit

Immunogen Species Human

Immunogen A phospho-specific peptide corresponding to residues surrounding Ser186 of human MAPK4 (AA183-190)

Conjugates

Alkaline Phosphatase, APC, ATTO 390, ATTO 488, ATTO 565, ATTO 594, ATTO 633, ATTO 655, ATTO 680, ATTO 700, Biotin, FITC, HRP, PE/ATTO 594, PerCP, RPE, Streptavidin, Unconjugated

Properties

Storage Buffer	PBS pH7.4, 50% glycerol, 0.025% Thimerosal
Storage Temperature	-20ºC
Shipping Temperature	Blue Ice or 4ºC
Purification	Peptide Affinity Purified
Clonality	Polyclonal
Specificity	Detects 62.623 kDa.
Cite This Product	StressMarq Biosciences Cat# SPC-976, RRID: AB_2707967
Certificate of Analysis	A 1:250 dilution of SPC-976 was sufficient for detection of MAPK4 (pSer186) in 10 µg of mouse brain lysate by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.

Biological Description

Alternative Names	ERK4 Antibody, ERK3 Antibody, ERK3 related Antibody, MAPK4 Antibody, Extracellular signal regulated kinase 4 Antibody, MAP kinase 4 Antibody, MAP kinase isoform p63 Antibody, MAPK4 Antibody, Mitogen activated protein kinase 4 Antibody, MK04_HUMAN Antibody, p63MAPK Antibody, PRKM4 Antibody
Cellular Localization	Cytoplasm, Nucleus
Accession Number	NP_002738
Gene ID	5596
Swiss Prot	P31152
Scientific Background	MAPK4 is a protein-serine/threonine kinase that phosphorylates microtubule-associated protein 2 (MAP2) and MAPKAPK5. The precise role of the complex formed with MAPKAPK5 is still unclear, but the complex follows a complex set of phosphorylation events: upon interaction with atypical MAPKAPK5, ERK4/MAPK4 is phosphorylated at Ser-186 and then mediates phosphorylation and activation of MAPKAPK5, which in turn phosphorylates ERK4/MAPK4. MAPK4 may promote entry in the cell cycle.

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PE/ATTO 594

PE/ATTO 594 is a tandem conjugate, where PE is excited at 535 nm and transfers energy to ATTO 594 via FRET (fluorescence resonance energy transfer), which emits at 627 nm.

Overview:

High fluorescence yield
High photostability
Very hydrophilic
Excellent solubility in water
Very little aggregation

PE/ATTO 594 Datasheet

PE-ATTO 594 Fluorophore Conjugate Excitation and Emission Spectra

Optical Properties:

λ_ex = 535 nm

λ_em = 627 nm

Laser = 488 to 561 nm

品牌介绍

StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究，同时在其他领域也取得了一定成就，包括翻译后修饰，提供甲基化与乙酰基化抗体。其中，细胞应激领域主要包括热休克蛋白（HSP）领域。我们公司不仅在热休克蛋白领域领先全球，而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列，分别涉及抗体、蛋白、酶联免疫吸附试验（ELISA）试剂盒及小分子领域。

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