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当前位置: 首页 > 产品中心 > acid_base_buffer_solution > StressMarq/Anti-LYN Antibody (pTyr508)/SPC-1012D-A488/100-µl
商品详细StressMarq/Anti-LYN Antibody (pTyr508)/SPC-1012D-A488/100-µl
StressMarq/Anti-LYN Antibody (pTyr508)/SPC-1012D-A488/100-µl
StressMarq/Anti-LYN Antibody (pTyr508)/SPC-1012D-A488/100-µl
商品编号: SPC-1012D-A488
市场价: ¥6840.00
美元价: 4104.00
产地: 美国(厂家直采)
公司:
产品分类: 酸碱缓冲液
公司分类: acid_base_buffer_solution
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

Overview:

Product Name LYN Antibody (pTyr508)
Description

Rabbit Anti-Human LYN (pTyr508) Polyclonal

Species Reactivity Human
Applications WB, AM
Antibody Dilution WB (1:250); optimal dilutions for assays should be determined by the user.
Host Species Rabbit
Immunogen Species Human
Immunogen A phospho-specific peptide corresponding to residues surrounding Tyr508 of human Lyn (AA505-511)
Conjugates Alkaline Phosphatase, APC, ATTO 390, ATTO 488, ATTO 565, ATTO 594, ATTO 633, ATTO 655, ATTO 680, ATTO 700, Biotin, FITC, HRP, PE/ATTO 594, PerCP, RPE, Streptavidin, Unconjugated

Properties

Storage Buffer PBS pH7.4, 50% glycerol, 0.025% Thimerosal
Storage Temperature -20ºC
Shipping Temperature Blue Ice or 4ºC
Purification Peptide Affinity Purified
Clonality Polyclonal
Specificity Detects 58.443 kDa.
Cite This Product StressMarq Biosciences Cat# SPC-1012, RRID: AB_2708615
Certificate of Analysis A 1:250 dilution of SPC-1012 was sufficient for detection of LYN (pTyr508) in 10 µg of human A431 cell lysate by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.

Biological Description

Alternative Names AA407514 antibody, Hck 2 antibody, JTK 8 antibody, Lck/Yes related novel protein tyrosine kinase antibody, LYN antibody, LYN_HUMAN antibody, p53Lyn antibody, Tyrosine protein kinase LYN antibody
Cellular Localization Cytoplasm, Cell membrane, Nucleus
Accession Number NP_002341
Gene ID 4067
Swiss Prot P07948
Scientific Background LYN is a protein-tyrosine kinase. It is involved in regulation of innate and adaptive immune response, cell degranulation and hematopoiesis. It is also involved in signal transduction induced by growth factors, cytokines and integrin signalling. It also responds to DNA damage and genotoxic agents. Its regulations many aspects of the cell depending on cell type and context. Lyn has been associated with increase in invasiveness and mestasis of breast cancer cells.

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  ATTO 488
Overview:

  • High fluorescence yield
  • High photostability
  • Very hydrophilic
  • Excellent solubility in water
  • Very little aggregation
  • New dye with net charge of -1
  • Molar Mass: 804 g/mol 

ATTO 488 Datasheet

  ATTO 488 Fluorophore Excitation and Emission SpectraOptical Properties:

λex = 501 nm

λem = 523 nm

εmax = 9.0×104

Φf = 0.80

τfl = 4.1 ns

Brightness = 72

Laser = 488 nm

Filter set = FITC

 

品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究,同时在其他领域也取得了一定成就,包括翻译后修饰,提供甲基化与乙酰基化抗体。其中,细胞应激领域主要包括热休克蛋白(HSP)领域。我们公司不仅在热休克蛋白领域领先全球,而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列,分别涉及抗体、蛋白、酶联免疫吸附试验(ELISA)试剂盒及小分子领域。