StressMarq/LY364947/SIH-504-5MG/5-mg
商品编号：
SIH-504-5MG
市场价：
¥1600.00
美元价：
960.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Overview:
| ProductName | LY364947 |
| Description | ALK5kinaseinhibitor |
| Purity | >98%(HPLC) |
| CASNo. | 396129-53-6 |
| MolecularFormula | C17H12N4 |
| MolecularWeight | 272.3 |
Properties
| StorageTemperature | -20ºC |
| ShippingTemperature | ShippedAmbient |
| ProductType | Inhibitor |
| Solubility | Solubleto100mMinDMSO |
| Source | Synthetic |
| Appearance | Yellowtobrownsolid |
| SMILES | C1=CC=C2C(=C1)C(=CC=N2)C3=CNN=C3C4=CC=CC=N4 |
| InChI | InChI=1S/C17H12N4/c1-2-6-15-13(5-1)12(8-10-19-15)14-11-20-21-17(14)16-7-3-4-9-18-16/h1-11H,(H,20,21) |
| InChIKey | IBCXZJCWDGCXQT-UHFFFAOYSA-N |
| SafetyPhrases | Classification:Acutetoxicity,Oral(Category3),H301Skinirritation(Category2),H315Eyeirritation(Category2A),H319Specifictargetorgantoxicity-singleexposure(Category3),Respiratorysystem,H335Acuteaquatictoxicity(Category1),H400Chronicaquatictoxicity(Category1),H410SafetyPhrases:S22-Donotbreathedust.S24/25-Avoidcontactwithskinandeyes.S36/37/39-Wearsuitableprotectiveclothing,glovesandeye/faceprotection.Hazardstatements:H301Toxicifswallowed.H315Causesskinirritation.H319Causesseriouseyeirritation.H335Maycauserespiratoryirritation.H410Verytoxictoaquaticlifewithlonglastingeffects.Precautionarystatements:P261Avoidbreathingdust/fume/gas/mist/vapours/spray.P264Washskinthoroughlyafterhandling.P270Donoteat,drinkorsmokewhenusingthisproduct.P271Useonlyoutdoorsorinawell-ventilatedarea.P273Avoidreleasetotheenvironment.P280Wearprotectivegloves/eyeprotection/faceprotection.P301+P310IFSWALLOWED:ImmediatelycallaPOISONCENTERordoctor/physician.P302+P352IFONSKIN:Washwithplentyofsoapandwater.P304+P340IFINHALED:Removevictimtofreshairandkeepatrestinapositioncomfortableforbreathing.P305+P351+P338IFINEYES:Rinsecautiouslywithwaterforseveralminutes.Removecontactlenses,ifpresentandeasytodo.Continuerinsing.P312CallaPOISONCENTERordoctor/physicianifyoufeelunwell.P321Specifictreatment(seesupplementalfirstaidinstructionsonthislabel).P330Rinsemouth.P332+P313Ifskinirritationoccurs:Getmedicaladvice/attention.P337+P313Ifeyeirritationpersists:Getmedicaladvice/attention.P362Takeoffcontaminatedclothingandwashbeforereuse.P391Collectspillage.P403+P233Storeinawell-ventilatedplace.Keepcontainertightlyclosed.P405Storelockedup.P501Disposeofcontents/containertoanapprovedwastedisposalplant. |
| CiteThisProduct | LY364947(StressMarqBiosciencesInc.,VictoriaBCCANADA,Catalog#SIH-504) |
BIOLOGicalDescription
| AlternativeNames | LY364947,HTS466284,ALK5InhibitorI,4-[3-(2-pyridinyl)-1H-pyrazol-4-yl]-quinoline,HTS466284,TransformingGrowthFactor-βTypeIReceptorKinaseInhibitor |
| ResearchAreas | Cancer,Apoptosis,CancerGrowthInhibitors,CellSignaling,TyrosineKinaseInhibitors |
| PubChemID | 447966 |
| ScientificBackground | LY364947isapotentandselectiveinhibitorofTGF-βtype-1receptorkinase.Specifically,itinhibitsTGF-βsignalingandgenetranscription.LY364947iscellpermeableandATP-competitive. |
| References | 1.VogtJ.,TraynorR.,&SapkotaG.P.(2011)Cell.Signal.23(11):1831–1842. |
ProductImages
ChemicalstructureofLY364947(SIH-504),aALK5kinaseinhibitor.CAS#:396129-53-6.MolecularFormula:C17H12N4.MolecularWeight:272.3g/mol.
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品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究，同时在其他领域也取得了一定成就，包括翻译后修饰，提供甲基化与乙酰基化抗体。其中，细胞应激领域主要包括热休克蛋白（HSP）领域。我们公司不仅在热休克蛋白领域领先全球，而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列，分别涉及抗体、蛋白、酶联免疫吸附试验（ELISA）试剂盒及小分子领域。
