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当前位置: 首页 > 产品中心 > acid_base_buffer_solution > StressMarq/Anti-LKB1 Antibody (pSer428)/SPC-1009D-A488/100-µl
商品详细StressMarq/Anti-LKB1 Antibody (pSer428)/SPC-1009D-A488/100-µl
StressMarq/Anti-LKB1 Antibody (pSer428)/SPC-1009D-A488/100-µl
StressMarq/Anti-LKB1 Antibody (pSer428)/SPC-1009D-A488/100-µl
商品编号: SPC-1009D-A488
市场价: ¥6840.00
美元价: 4104.00
产地: 美国(厂家直采)
公司:
产品分类: 酸碱缓冲液
公司分类: acid_base_buffer_solution
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

Overview:

Product Name LKB1 Antibody (pSer428)
Description

Rabbit Anti-Human LKB1 (pSer428) Polyclonal

Species Reactivity Human
Applications WB, AM
Antibody Dilution WB (1:250); optimal dilutions for assays should be determined by the user.
Host Species Rabbit
Immunogen Species Human
Immunogen A phospho-specific peptide corresponding to residues surrounding Ser428 of human LKB1 (STK11) (AA425-431)
Conjugates Alkaline Phosphatase, APC, ATTO 390, ATTO 488, ATTO 565, ATTO 594, ATTO 633, ATTO 655, ATTO 680, ATTO 700, Biotin, FITC, HRP, PE/ATTO 594, PerCP, RPE, Streptavidin, Unconjugated

Properties

Storage Buffer PBS pH7.4, 50% glycerol, 0.025% Thimerosal
Storage Temperature -20ºC
Shipping Temperature Blue Ice or 4ºC
Purification Peptide Affinity Purified
Clonality Polyclonal
Specificity Detects 48.636 kDa.
Cite This Product StressMarq Biosciences Cat# SPC-1009, RRID: AB_2708561
Certificate of Analysis A 1:250 dilution of SPC-1009 was sufficient for detection of LKB1 (pSer428) in 10 µg of HeLa cell lysate by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.

Biological Description

Alternative Names hLKB1 antibody, Liver kinase B1 antibody, LKB1 antibody, PJS antibody, Polarization related protein LKB1 antibody, Renal carcinoma antigen NY-REN-19 antibody, Serine/Threonine Kinase 11 antibody, Serine/threonine protein kinase STK11 antibody, Stk11 antibody, STK11_HUMAN antibody
Cellular Localization Cytoplasm, Nucleus
Accession Number NP_000446
Gene ID 6794
Swiss Prot Q15831
Scientific Background LKB1 is a protein-serine/threonine kinase. Phosphorylates and activates AMP-activated kinase (AMPK), AMPK involved in stress responses, lipid and glucose metabolism. Its mutation pattern in human tumours is very characteristic of a tumour suppressor protein.

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  ATTO 488
Overview:

  • High fluorescence yield
  • High photostability
  • Very hydrophilic
  • Excellent solubility in water
  • Very little aggregation
  • New dye with net charge of -1
  • Molar Mass: 804 g/mol 

ATTO 488 Datasheet

  ATTO 488 Fluorophore Excitation and Emission SpectraOptical Properties:

λex = 501 nm

λem = 523 nm

εmax = 9.0×104

Φf = 0.80

τfl = 4.1 ns

Brightness = 72

Laser = 488 nm

Filter set = FITC

 

品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究,同时在其他领域也取得了一定成就,包括翻译后修饰,提供甲基化与乙酰基化抗体。其中,细胞应激领域主要包括热休克蛋白(HSP)领域。我们公司不仅在热休克蛋白领域领先全球,而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列,分别涉及抗体、蛋白、酶联免疫吸附试验(ELISA)试剂盒及小分子领域。