STRESS MARQ/LH 846/SIH-503-5MG/5-mg
商品编号：
SIH-503-5MG
市场价：
¥1380.00
美元价：
828.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Overview:
| Product Name | LH 846 |
| Description | Casein kinase 1d inhibitor |
| Purity | >98% (HPLC) |
| CAS No. | 639052-78-1 |
| Molecular Formula | C16H13ClN2OS |
| Molecular Weight | 316.8 |
Properties
| Storage Temperature | -20ºC |
| Shipping Temperature | Shipped Ambient |
| Product Type | Inhibitor |
| Solubility | Soluble to 100 mM in DMSO |
| Source | Synthetic |
| Appearance | White to beige powder |
| SMILES | CC1=CC2=C(C=C1Cl)N=C(S2)NC(=O)CC3=CC=CC=C3 |
| InChI | InChI=1S/C16H13ClN2OS/c1-10-7-14-13(9-12(10)17)18-16(21-14)19-15(20)8-11-5-3-2-4-6-11/h2-7,9H,8H2,1H3,(H,18,19,20) |
| InChIKey | DYHAMRNAHTWYKY-UHFFFAOYSA-N |
| Safety Phrases | Classification: Acute toxicity, Oral (Category 4) Chronic aquatic toxicity(Category 4)Safety Phrases: S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.Hazard statements: H302 Harmful if swallowed. H413 May cause long lasting harmful effects to aquatic life. |
| Cite This Product | LH 846 (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-503) |
Biological Description
| Alternative Names | LH846, LH-846, N-(5-Chloro-6-methyl-2-benzothiazolyl)benzeneacetamide |
| Research Areas | Cell Signaling |
| PubChem ID | 851474 |
| Scientific Background | LH 846 is a potent and selective inhibitor of Casein Kinase CK1δ. Specifically, it inhibits CK1δ-dependent phosphorylation and degradation of PER1 protein. CK1δ is a known regulator of circadian rhythm. |
| References | 1. Lee J.W., et al. (2011) Angewandte Chemie. 50(45): 10608–10611. |
Product Images
Chemical structure of LH 846 (SIH-503), a Casein kinase 1d inhibitor. CAS #: 639052-78-1. Molecular Formula: C16H13ClN2OS. Molecular Weight: 316.8 g/mol.
Product Citations (0)
Currently there are no citations for this product.
品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究，同时在其他领域也取得了一定成就，包括翻译后修饰，提供甲基化与乙酰基化抗体。其中，细胞应激领域主要包括热休克蛋白（HSP）领域。我们公司不仅在热休克蛋白领域领先全球，而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列，分别涉及抗体、蛋白、酶联免疫吸附试验（ELISA）试剂盒及小分子领域。
