StressMarq/Lestaurtinib/SIH-460-5MG/5-mg
商品编号：
SIH-460-5MG
市场价：
¥9500.00
美元价：
5700.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Overview:
| ProductName | Lestaurtinib |
| Description | FLT3,TrkAkinaseinhibitor |
| Purity | >98%(HPLC) |
| CASNo. | 111358-88-4 |
| MolecularFormula | C26H21N3O4 |
| MolecularWeight | 439.5 |
Properties
| StorageTemperature | -20ºC |
| ShippingTemperature | ShippedAmbient |
| ProductType | Inhibitor |
| Solubility | Solubleto100mMinDMSOandto25mMinethanol |
| Source | Synthetic |
| Appearance | Whitepowder |
| SMILES | [[email protected]@]67([N]2C1=C5C(=C4C(=C1C3=C2C=CC=C3)CNC4=O)C8=C([N]5[[email protected]](O6)C[[email protected]]7(O)CO)C=CC=C8)C |
| InChI | InChI=1S/C26H21N3O4/c1-25-26(32,12-30)10-18(33-25)28-16-8-4-2-6-13(16)20-21-15(11-27-24(21)31)19-14-7-3-5-9-17(14)29(25)23(19)22(20)28/h2-9,18,30,32H,10-12H2,1H3,(H,27,31)/t18-,25+,26+/m1/s1 |
| InChIKey | UIARLYUEJFELEN-LROUJFHJSA-N |
| SafetyPhrases | Classification:Notahazardoussubstanceormixture.SafetyPhrases:S22-Donotbreathedust.S24/25-Avoidcontactwithskinandeyes.S36/37/39-Wearsuitableprotectiveclothing,glovesandeye/faceprotection. |
| CiteThisProduct | Lestaurtinib(StressMarqBiosciencesInc.,VictoriaBCCANADA,Catalog#SIH-460) |
BIOLOGicalDescription
| AlternativeNames | KT5555,CEP-701,(9S,10S,12R)-2,3,9,10,11,12-Hexahydro-10-hydroxy-10-(hydroxymethyl)-9-methyl-9,12-epoxy-1H-diindolo[1,2,3-fg:3",2",1"-kl]pyrrolo[3,4-i][1,6]benzodiazocin-1-one |
| ResearchAreas | Cancer,Apoptosis,CancerGrowthInhibitors,CellSignaling,TyrosineKinaseInhibitors |
| PubChemID | 126565 |
| ScientificBackground | LestaurtinibispotentJAK2,FLT3andTrkAreceptortyrosinekinaseinhibitor.Specifically,itpreventsSTAT5phosphorylation.Lestaurtinibexhibitsantiproliferativeactivityinvitro. |
| References | 1.WeiselK.C.,etal.(2007)Ann.NYAcad.Sci.1106:190–196. 2.HexnerE.O.,etal.(2008)Blood.111(12):5663–5671. |
ProductImages
ChemicalstructureofLestaurtinib(SIH-460),aFLT3/TrkAkinaseinhibitor.CAS#:111358-88-4.MolecularFormula:C26H21N3O4.MolecularWeight:439.5g/mol.
ProductCitations(0)
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品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究，同时在其他领域也取得了一定成就，包括翻译后修饰，提供甲基化与乙酰基化抗体。其中，细胞应激领域主要包括热休克蛋白（HSP）领域。我们公司不仅在热休克蛋白领域领先全球，而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列，分别涉及抗体、蛋白、酶联免疫吸附试验（ELISA）试剂盒及小分子领域。
