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当前位置: 首页 > 产品中心 > acid_base_buffer_solution > StressMarq/Lestaurtinib/SIH-460-1MG/1-mg
商品详细StressMarq/Lestaurtinib/SIH-460-1MG/1-mg
StressMarq/Lestaurtinib/SIH-460-1MG/1-mg
StressMarq/Lestaurtinib/SIH-460-1MG/1-mg
商品编号: SIH-460-1MG
市场价: ¥3000.00
美元价: 1800.00
产地: 美国(厂家直采)
公司:
产品分类: 酸碱缓冲液
公司分类: acid_base_buffer_solution
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

Overview:

ProductNameLestaurtinib
Description

FLT3,TrkAkinaseinhibitor

Purity>98%(HPLC)
CASNo.111358-88-4
MolecularFormulaC26H21N3O4
MolecularWeight439.5

Properties

StorageTemperature-20ºC
ShippingTemperatureShippedAmbient
ProductTypeInhibitor
SolubilitySolubleto100mMinDMSOandto25mMinethanol
SourceSynthetic
AppearanceWhitepowder
SMILES[[email protected]@]67([N]2C1=C5C(=C4C(=C1C3=C2C=CC=C3)CNC4=O)C8=C([N]5[[email protected]](O6)C[[email protected]]7(O)CO)C=CC=C8)C
InChIInChI=1S/C26H21N3O4/c1-25-26(32,12-30)10-18(33-25)28-16-8-4-2-6-13(16)20-21-15(11-27-24(21)31)19-14-7-3-5-9-17(14)29(25)23(19)22(20)28/h2-9,18,30,32H,10-12H2,1H3,(H,27,31)/t18-,25+,26+/m1/s1
InChIKeyUIARLYUEJFELEN-LROUJFHJSA-N
SafetyPhrasesClassification:Notahazardoussubstanceormixture.SafetyPhrases:S22-Donotbreathedust.S24/25-Avoidcontactwithskinandeyes.S36/37/39-Wearsuitableprotectiveclothing,glovesandeye/faceprotection.
CiteThisProductLestaurtinib(StressMarqBiosciencesInc.,VictoriaBCCANADA,Catalog#SIH-460)

BIOLOGicalDescription

AlternativeNamesKT5555,CEP-701,(9S,10S,12R)-2,3,9,10,11,12-Hexahydro-10-hydroxy-10-(hydroxymethyl)-9-methyl-9,12-epoxy-1H-diindolo[1,2,3-fg:3",2",1"-kl]pyrrolo[3,4-i][1,6]benzodiazocin-1-one
ResearchAreasCancer,Apoptosis,CancerGrowthInhibitors,CellSignaling,TyrosineKinaseInhibitors
PubChemID126565
ScientificBackgroundLestaurtinibispotentJAK2,FLT3andTrkAreceptortyrosinekinaseinhibitor.Specifically,itpreventsSTAT5phosphorylation.Lestaurtinibexhibitsantiproliferativeactivityinvitro.
References1.WeiselK.C.,etal.(2007)Ann.NYAcad.Sci.1106:190–196.
2.HexnerE.O.,etal.(2008)Blood.111(12):5663–5671.

ProductImages

<p>Chemical structure of Lestaurtinib (SIH-460), a FLT3/ TrkA kinase inhibitor. CAS #: 111358-88-4. Molecular Formula: C26H21N3O4. Molecular Weight: 439.5 g/mol.</p>

ChemicalstructureofLestaurtinib(SIH-460),aFLT3/TrkAkinaseinhibitor.CAS#:111358-88-4.MolecularFormula:C26H21N3O4.MolecularWeight:439.5g/mol.

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品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究,同时在其他领域也取得了一定成就,包括翻译后修饰,提供甲基化与乙酰基化抗体。其中,细胞应激领域主要包括热休克蛋白(HSP)领域。我们公司不仅在热休克蛋白领域领先全球,而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列,分别涉及抗体、蛋白、酶联免疫吸附试验(ELISA)试剂盒及小分子领域。