StressMarq/LDN-57444/SIH-332-50MG/50-mg
商品编号：
SIH-332-50MG
市场价：
¥8220.00
美元价：
4932.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Overview:
| ProductName | LDN-57444 |
| Description | DUBinhibitor |
| Purity | >98% |
| CASNo. | 668467-91-2 |
| MolecularFormula | C17H11Cl3N2O3 |
| MolecularWeight | 397.6 |
Properties
| StorageTemperature | -20ºC |
| ShippingTemperature | ShippedAmbient |
| ProductType | Inhibitor |
| Solubility | Solublein20mg/mlDMSO |
| Source | Synthetic |
| Appearance | YellowPowder |
| SMILES | CC(=O)O/N=C1/C2=C(C=CC(=C2)Cl)N(C1=O)CC3=C(C=CC(=C3)Cl)Cl |
| InChI | InChI=1S/C17H11Cl3N2O3/c1-9(23)25-21-16-13-7-12(19)3-5-15(13)22(17(16)24)8-10-6-11(18)2-4-14(10)20/h2-7H,8H2,1H3/b21-16- |
| InChIKey | OPQRFPHLZZPCCH-PGMHBOJBSA-N |
| SafetyPhrases | Classification:Caution:Substancenotyetfullytested.SafetyPhrases:S22-DonotbreathedustS36/37/39-Wearsuitableprotectiveclothing,glovesandeye/faceprotectionS24/25-AvoidcontactwithskinandeyesHazardStatements:H302–HarmfulifswallowedH317–MaycauseanallergicskinreactionPrecautionaryStatements:P280–Wearprotectivegloves. |
| CiteThisProduct | LDN-57444(StressMarqBiosciencesInc.,VictoriaBCCANADA,Catalog#SIH-332) |
BIOLOGicalDescription
| AlternativeNames | 3-(O-acetyloxime),5-chloro-1-[(2,5-dichlorophenyl)methyl]-1H-Indole-2,3-dione,C30,LDN57444 |
| ResearchAreas | Cancer,Apoptosis |
| PubChemID | 16760696 |
| ScientificBackground | InhibitsubiquitinC-terminalhydrolase(UCH-L1)(Ki=0.4M).Decreasesproteasomeactivityandincreaseslevelsofubiquitinatedproteins.Inducesapoptosis.Causesdramaticalterationsinsynapticproteindistributionandspinemorphologyinvivo.Cellpermeable. |
| References | 1. LiuY.,etal.(2003)Chem.Biol.10:837. 2.TanY.Y.,etal.(2008)Mol.Cell.Biochem.318:109. 3.CartierA.E.,etal.(2009)J.Neurosci.29:7857. |
ProductImages
ChemicalstructureofLDN-57444(SIH-332),aDUBinhibitor.CAS#:668467-91-2.MolecularFormula:C17H11Cl3N2O3.MolecularWeight:397.6g/mol.
ProductCitations(0)
Currentlytherearenocitationsforthisproduct.
品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究，同时在其他领域也取得了一定成就，包括翻译后修饰，提供甲基化与乙酰基化抗体。其中，细胞应激领域主要包括热休克蛋白（HSP）领域。我们公司不仅在热休克蛋白领域领先全球，而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列，分别涉及抗体、蛋白、酶联免疫吸附试验（ELISA）试剂盒及小分子领域。
