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当前位置: 首页 > 产品中心 > acid_base_buffer_solution > StressMarq/Anti-LC3C Antibody [VB2]/SMC-212A-A633/50-µg
商品详细StressMarq/Anti-LC3C Antibody [VB2]/SMC-212A-A633/50-µg
StressMarq/Anti-LC3C Antibody [VB2]/SMC-212A-A633/50-µg
StressMarq/Anti-LC3C Antibody [VB2]/SMC-212A-A633/50-µg
商品编号: SMC-212A-A633
市场价: ¥6640.00
美元价: 3984.00
产地: 美国(厂家直采)
公司:
产品分类: 酸碱缓冲液
公司分类: acid_base_buffer_solution
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

Overview:

ProductNameLC3CAntibody
Description

MouseAnti-HumanLC3CMonoclonalIgG1

SpeciesReactivityHuman,Mouse,Rat
ApplicationsWB,IP
AntibodyDilutionWB(1:1000),ICC/IF(1:100);optimaldilutionsforassaysshouldbedeterminedbytheuser.
HostSpeciesMouse
ImmunogenSpeciesHuman
ImmunogenPeptidederivedfromC-terminalregionofhumanLC3Cprotein
Concentration1mg/ml
ConjugatesAlkalinePhosphatase,APC,ATTO390,ATTO488,ATTO565,ATTO594,ATTO633,ATTO655,ATTO680,ATTO700,Biotin,FITC,HRP,PE/ATTO594,PerCP,RPE,Streptavidin,Unconjugated

Properties

StorageBuffer10mMsodiumphosphate,pH7.2,150mMNaCl,0.02%sodiumazide
StorageTemperature-20ºC,4ºC
ShippingTemperatureBlueIceor4ºC
PurificationProteinGPurified
ClonalityMonoclonal
CloneNumberVB2
IsotypeIgG1
SpecificitySpecificforLC3C.DoesnotdetectLC3A,LC3B,GABARAP,GABARAPL1orGABARAPL2.
CiteThisProductStressMarqBiosciencesCat#SMC-212,RRID:AB_2699322
CertificateofAnalysisA1:20000dilutionofSMC-212wassufficientfordetectionofLC3CinlysatefromcellsexpressingrecombinantGST-taggedLC3CbyelectRochemiluminescenceanalysisusinggoatanti-mouseIgG:HRPasthesecondaryantibody.

BIOLOGicalDescription

AlternativeNamesMAP1LC3CAntibody,ATG8JAntibody,Autophagy-relatedproteinLC3CAntibody,Autophagy-relatedubiquitin-likemodifierLC3CAntibody,LC3likeprotein2Antibody,MAP1lightchain3likeprotein2Antibody,MAP1lightchain3likeprotein3Antibody,MAP1lightchain3-likeprotein3Antibody,MAP1A/MAP1BLC3CAntibody,MAP1A/MAP1Blightchain3CAntibody,MAP1LC3CAntibody,Microtubule-associatedprotein1lightchain3gammaAntibody,Microtubule-associatedproteins1A/1Blightchain3CAntibody,MLP3C_HUMANAntibody
ResearchAreasCancer,Autophagy
CellularLocalizationCytoplasm,Autophagosome,autophagosomemembrane,CytoplasmicVesicle,Cytoskeleton
AccessionNumberNP_001004343.1
GeneID440738
SwissProtQ9BXW4
ScientificBackgroundLightchain3(LC3)isamicrotubule-associatedproteinwithanapproximatemolecularmassof17kDa,andcanbefoundubiquitouslythroughoutmammaliantissue.LC3playsaroleinautophagy;oncetheautophagicprocessisinitiatedinacell,LC3isconjugatedtophosphatidylethanolaminetoformLC3-II.Thismoleculeisrecruitedtotheautophagosomeatthetimeoffusionwithlysosomes,andLC3-IIinautolysosomallumenisdegraded.Therefore,monitoringLC3isanimportanttoolfordetectingautophagyandautophagy-relatedprocesses.LC3Cisoneofthreeisoformswhichexhibitsthelowestexpressionrelativetotheothertwoisoforms.Itshighestexpressionisseeninplacenta,lungandovary.
References1.Tanida,I.,Ueno,T.,&Kominami,E.(2008).LC3andAutophagy.MethodsMolBiol.445:77-88.
2.He,H.,Dang,Y.,Dai,F.,Guo,Z.,Wu,J.,She,X.,etal.(2003).JBiolChem.278(31):29278-87.

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 ATTO633
Overview:
  • Highfluorescenceyield
  • HighthermalandphotostABIlity
  • Moderatelyhydrophilic
  • Goodsolubilityinpolarsolvents
  • StableatpH4–11
  • Cationicdye,perchloratesalt
  • MolarMass:652.2g/mol

ATTO633Datasheet

ATTO 633 Fluorophore Absorption and Emission SpectrumOpticalProperties:

λex =629nm

λem=657nm

εmax=1.3×105

Φf= 0.64

τfl =3.2ns

Brightness=83.2

Laser =633 nm

Filterset =Cy®5

 

品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究,同时在其他领域也取得了一定成就,包括翻译后修饰,提供甲基化与乙酰基化抗体。其中,细胞应激领域主要包括热休克蛋白(HSP)领域。我们公司不仅在热休克蛋白领域领先全球,而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列,分别涉及抗体、蛋白、酶联免疫吸附试验(ELISA)试剂盒及小分子领域。