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当前位置： 首页 > 产品中心 > acid_base_buffer_solution > StressMarq/Anti-LC3C Antibody [VB2]/SMC-212A-A565/50-µg
商品详细StressMarq/Anti-LC3C Antibody [VB2]/SMC-212A-A565/50-µg
StressMarq/Anti-LC3C Antibody [VB2]/SMC-212A-A565/50-µg
StressMarq/Anti-LC3C Antibody [VB2]/SMC-212A-A565/50-µg
商品编号： SMC-212A-A565
市场价： ¥6640.00
美元价： 3984.00
产地： 美国(厂家直采)
公司：
产品分类： 酸碱缓冲液
公司分类： acid_base_buffer_solution
联系Q Q： 3392242852
电话号码： 4000-520-616
电子邮箱： info@ebiomall.com
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商品介绍

Overview:

Product Name LC3C Antibody
Description

Mouse Anti-Human LC3C Monoclonal IgG1

Species Reactivity Human, Mouse, Rat
Applications WB, IP
Antibody Dilution WB (1:1000), ICC/IF (1:100); optimal dilutions for assays should be determined by the user.
Host Species Mouse
Immunogen Species Human
Immunogen Peptide derived from C-terminal region of human LC3C protein
Concentration 1 mg/ml
Conjugates Alkaline Phosphatase, APC, ATTO 390, ATTO 488, ATTO 565, ATTO 594, ATTO 633, ATTO 655, ATTO 680, ATTO 700, Biotin, FITC, HRP, PE/ATTO 594, PerCP, RPE, Streptavidin, Unconjugated

Properties

Storage Buffer 10 mM sodium phosphate, pH7.2, 150 mM NaCl, 0.02% sodium azide
Storage Temperature -20ºC, 4ºC
Shipping Temperature Blue Ice or 4ºC
Purification Protein G Purified
Clonality Monoclonal
Clone Number VB2
Isotype IgG1
Specificity Specific for LC3C. Does not detect LC3A, LC3B, GABARAP, GABARAPL1 or GABARAPL2.
Cite This Product StressMarq Biosciences Cat# SMC-212, RRID: AB_2699322
Certificate of Analysis A 1:20000 dilution of SMC-212 was sufficient for detection of LC3C in lysate from cells expressing recombinant GST-tagged LC3C by electrochemiluminescence analysis using goat anti-mouse IgG:HRP as the secondary antibody.

Biological Description

Alternative Names MAP1LC3C Antibody, ATG8J Antibody, Autophagy-related protein LC3 C Antibody, Autophagy-related ubiquitin-like modifier LC3 C Antibody, LC3 like protein 2 Antibody, MAP1 light chain 3 like protein 2 Antibody, MAP1 light chain 3 like protein 3 Antibody, MAP1 light chain 3-like protein 3 Antibody, MAP1A/MAP1B LC3 C Antibody, MAP1A/MAP1B light chain 3 C Antibody, MAP1LC3C Antibody, Microtubule-associated protein 1 light chain 3 gamma Antibody, Microtubule-associated proteins 1A/1B light chain 3C Antibody, MLP3C_HUMAN Antibody
Research Areas Cancer, Autophagy
Cellular Localization Cytoplasm, Autophagosome, autophagosome membrane, Cytoplasmic Vesicle, Cytoskeleton
Accession Number NP_001004343.1
Gene ID 440738
Swiss Prot Q9BXW4
Scientific Background Light chain 3 (LC3) is a microtubule-associated protein with an approximate molecular mass of 17kDa, and can be found ubiquitously throughout mammalian tissue. LC3 plays a role in autophagy; once the autophagic process is initiated in a cell, LC3 is conjugated to phosphatidylethanolamine to form LC3-II. This molecule is recruited to the autophagosome at the time of fusion with lysosomes, and LC3-II in autolysosomal lumen is degraded. Therefore, monitoring LC3 is an important tool for detecting autophagy and autophagy-related processes. LC3C is one of three isoforms which exhibits the lowest expression relative to the other two isoforms. Its highest expression is seen in placenta, lung and ovary.
References 1. Tanida, I., Ueno, T., & Kominami, E. (2008). LC3 and Autophagy. Methods Mol Biol. 445: 77-88.
2. He, H., Dang, Y., Dai, F., Guo, Z., Wu, J., She, X., et al. (2003). J Biol Chem. 278(31): 29278-87.

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 ATTO 565
Overview:

  • High fluorescence yield
  • High thermal and photostability
  • Good solubility in polar solvents
  • Excellent solubility in water
  • Very little aggregation
  • Rhodamine dye derivative
  • Molar Mass: 611 g/mol

ATTO 565 Datasheet

 ATTO 565 Fluorophore Excitation and Emission SpectraOptical Properties:

λex = 563 nm

λem = 592 nm

εmax = 1.2×105

Φf = 0.9

τfl = 3.4 n

Brightness = 10

Laser = 532 nm

Filter set = TRITC

 

品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究，同时在其他领域也取得了一定成就，包括翻译后修饰，提供甲基化与乙酰基化抗体。其中，细胞应激领域主要包括热休克蛋白（HSP）领域。我们公司不仅在热休克蛋白领域领先全球，而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列，分别涉及抗体、蛋白、酶联免疫吸附试验（ELISA）试剂盒及小分子领域。
公司介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究，同时在其他领域也取得了一定成就，包括翻译后修饰，提供甲基化与乙酰基化抗体。其中，细胞应激领域主要包括热休克蛋白（HSP）领域。我们公司不仅在热休克蛋白领域领先全球，而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列，分别涉及抗体、蛋白、酶联免疫吸附试验（ELISA）试剂盒
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CLIA套件 兴奋剂 敌手 抑制剂 蛋白质 活化剂 抗氧化剂 氧化还原探针 多克隆
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