StressMarq/KT 5823/SIH-458-500UG/500-µg
商品编号：
SIH-458-500UG
市场价：
¥9000.00
美元价：
5400.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Overview:
| ProductName | KT5823 |
| Description | PKGkinaseinhibitor |
| Purity | >98%(TLC) |
| CASNo. | 126643-37-6 |
| MolecularFormula | C29H25N3O5 |
| MolecularWeight | 495.5 |
Properties
| StorageTemperature | -20ºC |
| ShippingTemperature | ShippedAmbient |
| ProductType | Inhibitor |
| Solubility | SolubleinDMSO(20mg/ml),dimethylformamide(20mg/ml)andethylacetate(5mg/ml) |
| Source | Synthetic |
| Appearance | Whitesolid |
| SMILES | [N]47C1=C(C6=C(C2=C1[N](C3=CC=CC=C23)[[email protected]@H]5O[[email protected]]4([[email protected]@](C5)(OC)C(=O)OC)C)C(N(C6)C)=O)C8=C7C=CC=C8 |
| InChI | InChI=1S/C29H25N3O5/c1-28-29(36-4,27(34)35-3)13-20(37-28)31-18-11-7-5-9-15(18)22-23-17(14-30(2)26(23)33)21-16-10-6-8-12-19(16)32(28)25(21)24(22)31/h5-12,20H,13-14H2,1-4H3 |
| InChIKey | QTYMDECKVKSGSM-UHFFFAOYSA-N |
| SafetyPhrases | Classification:Notahazardoussubstanceormixture.SafetyPhrases:S22-Donotbreathedust.S24/25-Avoidcontactwithskinandeyes.S36/37/39-Wearsuitableprotectiveclothing,glovesandeye/faceprotection. |
| CiteThisProduct | KT5823(StressMarqBiosciencesInc.,VictoriaBCCANADA,Catalog#SIH-458) |
BIOLOGicalDescription
| AlternativeNames | (9S,10R,12R)-2,3,9,10,11,12-Hexahydro-10-methoxy-2,9-dimethyl-1-oxo-9,12-epoxy-1H-diindolo[1,2,3-fg:3",2",1"-kl]pyrrolo[3,4-i][1,6]benzodiazocine-10-carboxylicacid,methylester |
| ResearchAreas | Cancer,Apoptosis,CancerGrowthInhibitors,CellSignaling,TyrosineKinaseInhibitors |
| PubChemID | 3843 |
| ScientificBackground | KT5823isapotent,selective,andreversIBLeinhibitorofProteinKinaseG(PKG).ItisaderivativeofK-252a.KT5823hasbeenshowntoinhibitSNP-stimulatedPKGactivityindispersedsmoothmusclecells.Ithasalsobeenobservedtodose-dependentlyinhibitspontaneousapoptosisofneutrophils. |
| References | 1.MurthyK.S.,&MakhloufG.M.(1995)AmJ.Phys.268(1Pt1):C171–180. 2.BrunettiM.,etal.(2002)Biochem.Biophys.Res.Comm.297(3):498–501. 3.KaseH.,etal.(1987)Biochem.Biophys.Res.Comm.142(2):436–440. |
ProductImages
ChemicalstructureofKT5823(SIH-458),aPKGkinaseinhibitor.CAS#:126643-37-6.MolecularFormula:C29H25N3O5.MolecularWeight:495.5g/mol.
ProductCitations(0)
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品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究，同时在其他领域也取得了一定成就，包括翻译后修饰，提供甲基化与乙酰基化抗体。其中，细胞应激领域主要包括热休克蛋白（HSP）领域。我们公司不仅在热休克蛋白领域领先全球，而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列，分别涉及抗体、蛋白、酶联免疫吸附试验（ELISA）试剂盒及小分子领域。
