StressMarq/Anti-KCNQ1 Antibody [S37A-10]/SMC-307D-RPE/100-µg-免疫在线蚂蚁淘旗下平台

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商品详细StressMarq/Anti-KCNQ1 Antibody [S37A-10]/SMC-307D-RPE/100-µg

StressMarq/Anti-KCNQ1 Antibody [S37A-10]/SMC-307D-RPE/100-µg

商品编号： SMC-307D-RPE

品牌： StressMarq Biosciences

市场价： ¥6760.00

美元价： 4056.00

产地：美国(厂家直采)

公司：

产品分类：酸碱缓冲液

公司分类： acid_base_buffer_solution

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Overview:

ProductName KCNQ1Antibody

Description

MouseAnti-HumanKCNQ1MonoclonalIgG1

SpeciesReactivity Human,Mouse,Rat,Hamster

Applications WB,IHC,ICC/IF,IP,AM

AntibodyDilution WB(1:1000),IHC(1:1000),ICC/IF(1:100);optimaldilutionsforassaysshouldbedeterminedbytheuser.

HostSpecies Mouse

ImmunogenSpecies Human

Immunogen Fusionproteinaminoacids2-101ofhumanKCNQ1

Concentration 1mg/ml

Conjugates

AlkalinePhosphatase,APC,ATTO390,ATTO488,ATTO565,ATTO594,ATTO633,ATTO655,ATTO680,ATTO700,Biotin,FITC,HRP,PE/ATTO594,PerCP,RPE,Streptavidin,Unconjugated

Properties

StorageBuffer	PBSpH7.4,50%glycerol,0.09%sodiumazide
StorageTemperature	-20ºC
ShippingTemperature	BlueIceor4ºC
Purification	ProteinGPurified
Clonality	Monoclonal
CloneNumber	S37A-10
Isotype	IgG1
Specificity	Detects~75kDa.
CiteThisProduct	StressMarqBiosciencesCat#SMC-307,RRID:AB_2249571
CertificateofAnalysis	1µg/mlofSMC-307wassufficientfordetectionofKCNQ1in10µgofCOS-1celllysatetransientlyexpressingKCNQ1bycolorimetricimmunoblotanalysisusingGoatanti-mouseIgG:HRPasthesecondaryantibody.

BIOLOGicalDescription

AlternativeNames	ATFB1Antibody,ATFB3Antibody,FLJ26167Antibody,IKsproducingslowvoltage-gatedpotassiumchannelsubunitalphaAntibody,IKsproducingslowvoltage-gatedpotassiumchannelsubunitalphaKvLQT1Antibody,JervellandLange-Nielsensyndrome1Antibody,JLNS1Antibody,KCNA8Antibody,KCNA9Antibody,KCNQ1Antibody,KCNQ1_HUMANAntibody,kidneyandcardiacvoltagedependendK+channelAntibody,KQT-like1Antibody,Kv1.9Antibody,Kv7.1Antibody,KVLQT1Antibody,long(electrocardiographic)QTsyndromeAntibody,Ward-Romanosyndrome1Antibody,LQTAntibody,LQT1Antibody,Potassiumvoltage-gatedchannelsubfamilyKQTmember1Antibody,potassiumvoltage-gatedchannelKQT-likesubfamilymember1Antibody,RWSAntibody,slowdelayedrectifierchannelsubunitAntibody,SQT2Antibody,Voltage-gatedpotassiumchannelsubunitKv7.1Antibody,WRSAntibody
ResearchAreas	CardiovascularSystem,Heart,IonChannels,Neuroscience,PotassiumChannels,Voltage-GatedPotassiumChannels
CellularLocalization	Cellmembrane,Cytoplasmicvesiclemembrane
AccessionNumber	NP_000209.2
GeneID	3784
SwissProt	P51787
ScientificBackground	Kv7.1(KvLQT1)isapotassiumchannelproteincodedforbythegeneKCNQ1.Kv7.1ispresentinthecellmembranesofcardiacmuscletissueandininnerearneurons(1)amongothertissues.Inthecardiaccells,Kv7.1mediatestheIKs(orslowdelayedrectifyingK+)currentthatcontributestotherepolarizationofthecell,terminatingthecardiacactionpotentialandtherebytheheart"scontraction(2,3).
References	1.LangF.,VallonV.,KnipperM.,WagenmannP.(2007)AmJPhysiol.293(4):C1187-1208. 2.KurokawaJ.,etal.(2009)Channels(Austin).3(1):16-24. 3.SilvaJ.,andRudyY.(2005)Circulation.112(10):1384-1391.

ProductImages

<p>Immunohistochemistry analysis using Mouse Anti-KCNQ1 Monoclonal Antibody, Clone S37A-10 (SMC-307). Tissue: hippocampus. Species: Human. Fixation: Bouin’s Fixative and paraffin-embedded. Primary Antibody: Mouse Anti-KCNQ1 Monoclonal Antibody (SMC-307) at 1:1000 for 1 hour at RT. Secondary Antibody: FITC Goat Anti-Mouse (green) at 1:50 for 1 hour at RT.</p>

ImmunohistochemistryanalysisusingMouseAnti-KCNQ1MonoclonalAntibody,CloneS37A-10(SMC-307).Tissue:hippocampus.Species:Human.Fixation:Bouin’sFixativeandparaffin-embedded.PrimaryAntibody:MouseAnti-KCNQ1MonoclonalAntibody(SMC-307)at1:1000for1houratRT.SecondaryAntibody:FITCGoatAnti-Mouse(green)at1:50for1houratRT.

<p>Western Blot analysis of Human Cell lysates showing detection of KCNQ1 protein using Mouse Anti-KCNQ1 Monoclonal Antibody, Clone S37A-10 (SMC-307). Load: 15 µg protein. Block: 1.5% BSA for 30 minutes at RT. Primary Antibody: Mouse Anti-KCNQ1 Monoclonal Antibody (SMC-307) at 1:1000 for 2 hours at RT. Secondary Antibody: Sheep Anti-Mouse IgG: HRP for 1 hour at RT.</p>

WesternBlotanalysisofHumanCelllysatesshowingdetectionofKCNQ1proteinusingMouseAnti-KCNQ1MonoclonalAntibody,CloneS37A-10(SMC-307).Load:15µgprotein.Block:1.5%BSAfor30minutesatRT.PrimaryAntibody:MouseAnti-KCNQ1MonoclonalAntibody(SMC-307)at1:1000for2hoursatRT.SecondaryAntibody:SheepAnti-MouseIgG:HRPfor1houratRT.

<p>Immunohistochemistry analysis using Mouse Anti-KCNQ1 Monoclonal Antibody, Clone S37A-10 (SMC-307). Tissue: Brain Slice. Species: Mouse. Fixation: 10% Formalin Solution for 12-24 hours at RT. Primary Antibody: Mouse Anti-KCNQ1 Monoclonal Antibody (SMC-307) at 1:1000 for 1 hour at RT. Secondary Antibody: HRP/DAB Detection System: Biotinylated Goat Anti-Mouse, Streptavidin Peroxidase, DAB Chromogen (brown) for 30 minutes at RT. Counterstain: Mayer Hematoxylin (purple/blue) nuclear stain at 250-500 µl for 5 minutes at RT.</p>

ImmunohistochemistryanalysisusingMouseAnti-KCNQ1MonoclonalAntibody,CloneS37A-10(SMC-307).Tissue:BrainSlice.Species:Mouse.Fixation:10%FormalinSolutionfor12-24hoursatRT.PrimaryAntibody:MouseAnti-KCNQ1MonoclonalAntibody(SMC-307)at1:1000for1houratRT.SecondaryAntibody:HRP/DABDetectionSystem:BiotinylatedGoatAnti-Mouse,StreptavidinPeroxidase,DABChromogen(brown)for30minutesatRT.Counterstain:MayerHematoxylin(purple/blue)nuclearstainat250-500µlfor5minutesatRT.

<p>Western Blot analysis of hamster T-CHO cell lysate showing detection of KCNQ1 protein using Mouse Anti-KCNQ1 Monoclonal Antibody, Clone S37A-10 (SMC-307). Load: 15 µg protein. Block: 1.5% BSA for 30 minutes at RT. Primary Antibody: Mouse Anti-KCNQ1 Monoclonal Antibody (SMC-307) at 1:1000 for 2 hours at RT. Secondary Antibody: Sheep Anti-Mouse IgG: HRP for 1 hour at RT.</p>

WesternBlotanalysisofhamsterT-CHOcelllysateshowingdetectionofKCNQ1proteinusingMouseAnti-KCNQ1MonoclonalAntibody,CloneS37A-10(SMC-307).Load:15µgprotein.Block:1.5%BSAfor30minutesatRT.PrimaryAntibody:MouseAnti-KCNQ1MonoclonalAntibody(SMC-307)at1:1000for2hoursatRT.SecondaryAntibody:SheepAnti-MouseIgG:HRPfor1houratRT.

ProductCitations(2)

OtherCitations

BioMarkerAnalysiswithGratingCoupledSurfacePlasmonCoupledFluorescence.

Mendoza,A.,Dias,J.A.,Zeltner,T.andLawrence,D.A.(2014)JAdvBio&Biotech.1(1):1-22.

PubMedID:N/AReactivityHumanApplications:AntibodyMicroarray

BiomarkerAnalysiswithGratingCoupledSurfacePlasmonCoupledFluorescence.

Mendoza,A.,Dias,J.A.,Zeltner,T.andLawrence,D.A.(2014)JAdvBio&Biotech.1(1):1-22.

PubMedID:N/AReactivityMouseApplications:AntibodyMicroarray

R-PE(R-Phycoerythrin)

Overview:

Broadexcitationspectrum
Highquantumyield
Photostable
Memberofthephycobiliproteinfamily
Isolatedfromredalgae
Excellentsolubilityinwater
MolecularWeight:250kDa

R-PEDatasheet

R-PE Fluorophore Excitation and Emission Spectra

OpticalProperties:

λ_ex =565nm

λ_em=575nm

ε_max=2.0×10⁶

Φ_f= 0.84

Brightness=1.68x10³

Laser = 488to561nm

Filterset = TRITC

品牌介绍

StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究，同时在其他领域也取得了一定成就，包括翻译后修饰，提供甲基化与乙酰基化抗体。其中，细胞应激领域主要包括热休克蛋白（HSP）领域。我们公司不仅在热休克蛋白领域领先全球，而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列，分别涉及抗体、蛋白、酶联免疫吸附试验（ELISA）试剂盒及小分子领域。

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