StressMarq/K252B/SIH-456-100UG/100-µg
商品编号：
SIH-456-100UG
市场价：
¥2100.00
美元价：
1260.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Overview:
| ProductName | K252B |
| Description | Kinaseinhibitor |
| Purity | >98%(HPLC) |
| CASNo. | 99570-78-2 |
| MolecularFormula | C26H19N3O5 |
| MolecularWeight | 453.5 |
Properties
| StorageTemperature | -20ºC |
| ShippingTemperature | ShippedAmbient |
| ProductType | Inhibitor |
| Solubility | SolubleinDMSO(1mg/ml)ordimethylformamide(1mg/ml) |
| Source | Synthetic |
| Appearance | Whitesolid |
| SMILES | C[[email protected]]12[[email protected]@](C[[email protected]](O1)N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N2C7=C53)CNC6=O)(C(=O)O)O |
| InChI | InChI=1S/C26H19N3O5/c1-25-26(33,24(31)32)10-17(34-25)28-15-8-4-2-6-12(15)19-20-14(11-27-23(20)30)18-13-7-3-5-9-16(13)29(25)22(18)21(19)28/h2-9,17,33H,10-11H2,1H3,(H,27,30)(H,31,32)/t17-,25+,26+/m1/s1 |
| InChIKey | AMSOPBXQXSAAAC-PLZPTFKGSA-N |
| SafetyPhrases | Classification:Flammableliquids(Category4),H227SafetyPhrases:S22-Donotbreathedust.S24/25-Avoidcontactwithskinandeyes.S36/37/39-Wearsuitableprotectiveclothing,glovesandeye/faceprotection.Hazardstatements:H227CombustIBLeliquidPrecautionarystatements:P210Keepawayfromheat/sparks/openflames/hotsurfaces.-Nosmoking.P280Wearprotectivegloves/protectiveclothing/eyeprotection/faceprotection.P370+P378Incaseoffire:Usedrysand,drychemicaloralcohol-resistantfoamforextinction.P403+P235Storeinawell-ventilatedplace.Keepcool.P501Disposeofcontents/containertoanapprovedwastedisposalplant |
| CiteThisProduct | K252B(StressMarqBiosciencesInc.,VictoriaBCCANADA,Catalog#SIH-456) |
BIOLOGicalDescription
| AlternativeNames | (9S,10R,12R)-2,3,9,10,11,12-hexahydro-10-hydroxy-9-methyl-1-oxo-9,12-epoxy-1H-diindolo[1,2,3-fg:3",2",1"-kl]pyrrolo[3,4-i][1,6]benzodiazocine-10-carboxylicacid |
| ResearchAreas | Cancer,Apoptosis,CancerGrowthInhibitors,CellSignaling,TyrosineKinaseInhibitors |
| PubChemID | 9981344 |
| ScientificBackground | K252Bisanon-selective,proteinkinaseinhibitor.ItinhibitsCaMKII,MYLK,PKA,PKC,andcGKI.ItactsbybindingtotheATPbindingdomainofthekinase.K252Biscellpermeable. |
| References | 1.NakanishiS.,MatsudaY.,IwahashiK.,&KaseH.(1986)J.Antibiotics39(8):1066–1071. 2.TeshimaR.,etal.(1997)J.Immun.159(2):964–969. 3.KnüselB.,etal.(1992)J.NeuRochem.59(2):715–722. |
ProductImages
ChemicalstructureofK252B(SIH-456),aKinaseinhibitor(pan-specific).CAS#:99570-78-2.MolecularFormula:C26H19N3O5.MolecularWeight:453.5g/mol.
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品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究，同时在其他领域也取得了一定成就，包括翻译后修饰，提供甲基化与乙酰基化抗体。其中，细胞应激领域主要包括热休克蛋白（HSP）领域。我们公司不仅在热休克蛋白领域领先全球，而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列，分别涉及抗体、蛋白、酶联免疫吸附试验（ELISA）试剂盒及小分子领域。
