StressMarq/K252A/SIH-455-100UG/100-µg
商品编号：
SIH-455-100UG
市场价：
¥1180.00
美元价：
708.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Overview:
| ProductName | K252A |
| Description | Kinaseinhibitor |
| Purity | >98%(HPLC) |
| CASNo. | 99533-80-9 |
| MolecularFormula | C27H21N3O5 |
| MolecularWeight | 467.5 |
Properties
| StorageTemperature | -20ºC |
| ShippingTemperature | ShippedAmbient |
| ProductType | Inhibitor |
| Solubility | Solubleto25mMinDMSO |
| Source | Nonomuraealongicatena |
| Appearance | Whitesolid |
| SMILES | [N]47C1=C(C6=C(C2=C1[N](C3=CC=CC=C23)[[email protected]@H]5O[[email protected]]4(C(C5)(O)C(=O)OC)C)C(NC6)=O)C8=C7C=CC=C8 |
| InChI | InChI=1S/C27H21N3O5/c1-26-27(33,25(32)34-2)11-18(35-26)29-16-9-5-3-7-13(16)20-21-15(12-28-24(21)31)19-14-8-4-6-10-17(14)30(26)23(19)22(20)29/h4-10,18,33H,11-12H2,1-2H3,(H,28,31)/t18?,26-,27-/m1/s1 |
| InChIKey | KOZFSFOOLUUIGY-CYBHFKQVSA-N |
| SafetyPhrases | Classification:Notahazardoussubstanceormixture.SafetyPhrases:S22-Donotbreathedust.S24/25-Avoidcontactwithskinandeyes.S36/37/39-Wearsuitableprotectiveclothing,glovesandeye/faceprotection. |
| CiteThisProduct | K252A(StressMarqBiosciencesInc.,VictoriaBCCANADA,Catalog#SIH-455) |
BIOLOGicalDescription
| AlternativeNames | (9S,10R,12R)-2,3,9,10,11,12-Hexahydro-10-hydroxy-9-methyl-1-oxo-9,12-epoxy-1H-diindolo[1,2,3-fg:3",2",1"-kl]pyrrolo[3,4-i][1,6]benzodiazocine-10-carboxylicacidmethylester |
| ResearchAreas | Cancer,Apoptosis,CancerGrowthInhibitors,CellSignaling,TyrosineKinaseInhibitors |
| PubChemID | 11612445 |
| ScientificBackground | K252Aisanon-selectiveproteinkinaseinhibitorthatexhibitsawiderangeofeffects.Specifically,ithasbeenseentoinhibitPKA,PKC,PKG,CAMkinaseII,mlCK,Ser/Thrkinase,Met,andreceptortyrosinekinases.Ithasbeenshowntopreventautophosphorylationandactivationofdownstreameffectors. |
| References | 1.MorottiA.,MilaS.,Accorner,P.,TagliabueE.,&PonzettoC.(2002)Oncogene.21(32):4885–4893. 2.HashimotoY.,etal.(1991)Biochem.Biophys.Res.Comm.181(1):423–429. 3.RaychaudhuriS.P.,SanyalM.,WeltmanH.,&Kundu-RaychaudhuriS.(2004)J.Invest.Derm.122(3):812–819. |
ProductImages
ChemicalstructureofK252A(SIH-455),aKinaseinhibitor(pan-specific).CAS#:99533-80-9.MolecularFormula:C27H21N3O5.MolecularWeight:467.5g/mol.
ProductCitations(0)
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品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究，同时在其他领域也取得了一定成就，包括翻译后修饰，提供甲基化与乙酰基化抗体。其中，细胞应激领域主要包括热休克蛋白（HSP）领域。我们公司不仅在热休克蛋白领域领先全球，而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列，分别涉及抗体、蛋白、酶联免疫吸附试验（ELISA）试剂盒及小分子领域。
