StressMarq/IOX1/SIH-377-25MG/25-mg
商品编号：
SIH-377-25MG
市场价：
¥6780.00
美元价：
4068.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Overview:
| ProductName | IOX1 |
| Description | JMJDinhibitor |
| Purity | >98%(TLC);NMR(Conforms) |
| CASNo. | 5852-78-8 |
| MolecularFormula | C10H7NO3 |
| MolecularWeight | 189.2 |
Properties
| StorageTemperature | -20ºC |
| ShippingTemperature | ShippedAmbient |
| ProductType | Inhibitor |
| Solubility | MaybedissolvedinDMSO(20mg/ml) |
| Source | Synthetic |
| Appearance | Yellowpowder |
| SMILES | C1=CC2=C(C=CC(=C2N=C1)O)C(=O)O |
| InChI | InChI=1S/C10H7NO3/c12-8-4-3-7(10(13)14)6-2-1-5-11-9(6)8/h1-5,12H,(H,13,14) |
| InChIKey | JGRPKOGHYBAVMW-UHFFFAOYSA-N |
| SafetyPhrases | Classification:Caution:Substancenotyetfullytested.SafetyPhrases:S22-Donotbreathedust.S24/25-AvoidcontactwithskinandeyesS36/37/39-Wearsuitableprotectiveclothing,glovesandeye/faceprotection |
| CiteThisProduct | IOX1(StressMarqBiosciencesInc.,VictoriaBCCANADA,Catalog#SIH-377) |
BIOLOGicalDescription
| AlternativeNames | 8-Hydroxy-5-quinolinecarboxylicacid;(5-Carboxy-8HQ) |
| ResearchAreas | CellSignaling,Epigenetics |
| PubChemID | 459617 |
| ScientificBackground | IOX1isacellpermeableinhibitoroftheJMJDfamilyof2-oxoglutarate-dependenthistonedemethylases(IC50=0.12,0.07,0.2,0.3,0.6,and1MforJMJD3,JMJD1A,JMJD2A,JMJD2E,JMJD2CandUTXrespectively1).Itisabroadspectrum2-oxoglutarateoxygenaseinhibitorwhichmaybeusedtostudyhypoxicsignaling(1). |
| References | 1.KingO.N.,etal.(2010)PLoSOne.5:e15535. |
ProductImages
ChemicalstructureofIOX1(SIH-377),aJMJDinhibitor.CAS#:5852-78-8.MolecularFormula:C10H7NO3.MolecularWeight:189.2g/mol.
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品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究，同时在其他领域也取得了一定成就，包括翻译后修饰，提供甲基化与乙酰基化抗体。其中，细胞应激领域主要包括热休克蛋白（HSP）领域。我们公司不仅在热休克蛋白领域领先全球，而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列，分别涉及抗体、蛋白、酶联免疫吸附试验（ELISA）试剂盒及小分子领域。
