StressMarq/IOX1/SIH-377-5MG/5-mg
商品编号：
SIH-377-5MG
市场价：
¥1620.00
美元价：
972.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Overview:
| Product Name | IOX1 |
| Description | JMJD inhibitor |
| Purity | >98% (TLC); NMR (Conforms) |
| CAS No. | 5852-78-8 |
| Molecular Formula | C10H7NO3 |
| Molecular Weight | 189.2 |
Properties
| Storage Temperature | -20ºC |
| Shipping Temperature | Shipped Ambient |
| Product Type | Inhibitor |
| Solubility | May be dissolved in DMSO (20 mg/ml) |
| Source | Synthetic |
| Appearance | Yellow powder |
| SMILES | C1=CC2=C(C=CC(=C2N=C1)O)C(=O)O |
| InChI | InChI=1S/C10H7NO3/c12-8-4-3-7(10(13)14)6-2-1-5-11-9(6)8/h1-5,12H,(H,13,14) |
| InChIKey | JGRPKOGHYBAVMW-UHFFFAOYSA-N |
| Safety Phrases | Classification: Caution: Substance not yet fully tested. Safety Phrases: S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection |
| Cite This Product | IOX1 (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-377) |
Biological Description
| Alternative Names | 8-Hydroxy-5-quinolinecarboxylic acid; (5-Carboxy-8HQ) |
| Research Areas | Cell Signaling, Epigenetics |
| PubChem ID | 459617 |
| Scientific Background | IOX1 is a cell permeable inhibitor of the JMJD family of 2-oxoglutarate-dependent histone demethylases (IC50 = 0.12, 0.07, 0.2, 0.3, 0.6, and 1 M for JMJD3, JMJD1A, JMJD2A, JMJD2E, JMJD2C and UTX respectively1). It is a broad spectrum 2-oxoglutarate oxygenase inhibitor which may be used to study hypoxic signaling (1). |
| References | 1. King O.N., et al. (2010) PLoS One. 5: e15535. |
Product Images
Chemical structure of IOX1 (SIH-377), a JMJD inhibitor. CAS #: 5852-78-8. Molecular Formula: C10H7 NO3. Molecular Weight: 189.2 g/mol.
Product Citations (0)
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品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究，同时在其他领域也取得了一定成就，包括翻译后修饰，提供甲基化与乙酰基化抗体。其中，细胞应激领域主要包括热休克蛋白（HSP）领域。我们公司不仅在热休克蛋白领域领先全球，而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列，分别涉及抗体、蛋白、酶联免疫吸附试验（ELISA）试剂盒及小分子领域。
