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当前位置: 首页 > 产品中心 > acid_base_buffer_solution > StressMarq/Indirubin-3′-monoxime/SIH-502-5MG/5-mg
商品详细StressMarq/Indirubin-3′-monoxime/SIH-502-5MG/5-mg
StressMarq/Indirubin-3′-monoxime/SIH-502-5MG/5-mg
StressMarq/Indirubin-3′-monoxime/SIH-502-5MG/5-mg
商品编号: SIH-502-5MG
市场价: ¥1900.00
美元价: 1140.00
产地: 美国(厂家直采)
公司:
产品分类: 酸碱缓冲液
公司分类: acid_base_buffer_solution
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

Overview:

Product Name Indirubin-3′-monoxime
Description

GSK, CDK kinase inhibitor

Purity >98% (HPLC)
CAS No. 160807-49-8
Molecular Formula C16H11N3O2
Molecular Weight 277.3

Properties

Storage Temperature -20ºC
Shipping Temperature Shipped Ambient
Product Type Inhibitor
Solubility Soluble to 100 mM in DMSO and to 100 mM in ethanol
Source Synthetic
Appearance Red solid
SMILES O=C/2/N=C1/C=CC=C/C1=C2c4c(NO)c3ccccc3n4
InChI InChI=1S/C16H11N3O2/c20-16-13(9-5-1-3-7-11(9)18-16)15-14(19-21)10-6-2-4-8-12(10)17-15/h1-8,17,19,21H
InChIKey LDEWQRSYYHTQRA-UHFFFAOYSA-N
Safety Phrases Classification: Not a hazardous substance or mixture.Safety Phrases: S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
Cite This Product Indirubin-3'-monoxime (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-502)

Biological Description

Alternative Names Indirubin-3'-monoxime, 3-[1,3-Dihydro-3-(hydroxyimino)-2H-indol-2-ylidene]-1,3-dihydro-2H-indol-2-one, Indirubin-3′-oxime
Research Areas Cancer, Apoptosis, Cancer Growth Inhibitors, Cell Signaling, Tyrosine Kinase Inhibitors
PubChem ID 5326739
Scientific Background Indirubin-3'-monoxime is an inhibitor of protein kinases and cyclin-dependent kinases. Specifically, it is a potent inhibitor of glycogen synthase kinase-3β (GSK-3β).
References 1. Damiens E., Baratte B., Marie D., Eisenbrand G., & Meijer L. (2001) Oncogene. 20(29): 3786–3797.

Product Images

<p>Chemical structure of Indirubin-3′-monoxime (SIH-502), a GSK-3b and CDK kinase inhibitor. CAS #: 160807-49-8. Molecular Formula: C16H11N3O2. Molecular Weight: 277.3 g/mol.</p>

Chemical structure of Indirubin-3′-monoxime (SIH-502), a GSK-3b and CDK kinase inhibitor. CAS #: 160807-49-8. Molecular Formula: C16H11N3O2. Molecular Weight: 277.3 g/mol.

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品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究,同时在其他领域也取得了一定成就,包括翻译后修饰,提供甲基化与乙酰基化抗体。其中,细胞应激领域主要包括热休克蛋白(HSP)领域。我们公司不仅在热休克蛋白领域领先全球,而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列,分别涉及抗体、蛋白、酶联免疫吸附试验(ELISA)试剂盒及小分子领域。