StressMarq/Imatinib mesylate/SIH-453-20MG/20-mg
商品编号:
SIH-453-20MG
市场价:
¥1100.00
美元价:
660.00
产品分类:
酸碱缓冲液
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
Overview:
ProductName | Imatinibmesylate |
Description | Kinaseinhibitor |
Purity | >98%(HPLC) |
CASNo. | 152459-95-5 |
MolecularFormula | C30H35N7O4S |
MolecularWeight | 589.7 |
Properties
StorageTemperature | -20ºC |
ShippingTemperature | ShippedAmbient |
ProductType | Inhibitor |
Solubility | SolubleH2O:soluble10mg/ml,clear |
Source | Synthetic |
Appearance | Whitetobeigesolid |
SMILES | C5=C(C1=CN=CC=C1)N=C(NC2=C(C=CC(=C2)NC(C3=CC=C(C=C3)CN4CCN(CC4)C)=O)C)N=C5 |
InChI | InChI=1S/C29H31N7O/c1-21-5-10-25(18-27(21)34-29-31-13-11-26(33-29)24-4-3-12-30-19-24)32-28(37)23-8-6-22(7-9-23)20-36-16-14-35(2)15-17-36/h4-13,18-19H,14-17,20H2,1-2H3,(H,32,37)(H,31,33,34) |
InChIKey | KTUFNOKKBVMGRW-UHFFFAOYSA-N |
SafetyPhrases | Classification:Acutetoxicity,Oral(Category4),H302SafetyPhrases:S22-Donotbreathedust.S24/25-Avoidcontactwithskinandeyes.S36/37/39-Wearsuitableprotectiveclothing,glovesandeye/faceprotection.Hazardstatements:H302Harmfulifswallowed.Precautionarystatements:P264Washskinthoroughlyafterhandling.P270Donoteat,drinkorsmokewhenusingthisproduct.P301+P312IFSWALLOWED:CallaPOISONCENTERordoctor/physicianifyoufeelunwell.P330Rinsemouth.P501Disposeofcontents/containertoanapprovedwastedisposalplant. |
CiteThisProduct | Imatinibmesylate(StressMarqBiosciencesInc.,VictoriaBCCANADA,Catalog#SIH-453) |
BIOLOGicalDescription
AlternativeNames | 4-[(4-Methyl-1-piperazinyl)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]-phenyl]benzamidemethanesulfonate,4-[(4-Methylpiperazin-1-yl)methyl]-N-(4-methyl-3-{[4-(pyridin-3-yl)pyrimidin-2-yl]amino}phenyl)benzamidemesylate,CGP57148,Genfatinib,Glivec,Imatinibmethanesulfonate,STI-571 |
ResearchAreas | Cancer,Apoptosis,CancerGrowthInhibitors,CellSignaling,TyrosineKinaseInhibitors |
PubChemID | 5291 |
ScientificBackground | Imatinibmesylateisatyrosinekinaseinhibitor.ItspecificallyinhibitsBcr-Abltyrosinekinase,andreceptortyrosinekinasesencodedbyc-kitandplatelet-derivedgrowthfactorreceptor(PDGFR)oncogenes. |
References | 1.KantarjianH.,etal.(2002).N.E.J.Med.346(9):645–652. |
ProductImages
ChemicalstructureofImatinibmesylate(SIH-453),aBCR-ABLkinaseinhibitor.CAS#:152459-95-5.MolecularFormula:C30H35N7O4S.MolecularWeight:589.7g/mol.
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品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究,同时在其他领域也取得了一定成就,包括翻译后修饰,提供甲基化与乙酰基化抗体。其中,细胞应激领域主要包括热休克蛋白(HSP)领域。我们公司不仅在热休克蛋白领域领先全球,而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列,分别涉及抗体、蛋白、酶联免疫吸附试验(ELISA)试剂盒及小分子领域。