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当前位置: 首页 > 产品中心 > acid_base_buffer_solution > StressMarq/Imatinib mesylate/SIH-453-20MG/20-mg
商品详细StressMarq/Imatinib mesylate/SIH-453-20MG/20-mg
StressMarq/Imatinib mesylate/SIH-453-20MG/20-mg
StressMarq/Imatinib mesylate/SIH-453-20MG/20-mg
商品编号: SIH-453-20MG
市场价: ¥1100.00
美元价: 660.00
产地: 美国(厂家直采)
公司:
产品分类: 酸碱缓冲液
公司分类: acid_base_buffer_solution
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

Overview:

ProductNameImatinibmesylate
Description

Kinaseinhibitor

Purity>98%(HPLC)
CASNo.152459-95-5
MolecularFormulaC30H35N7O4S
MolecularWeight589.7

Properties

StorageTemperature-20ºC
ShippingTemperatureShippedAmbient
ProductTypeInhibitor
SolubilitySolubleH2O:soluble10mg/ml,clear
SourceSynthetic
AppearanceWhitetobeigesolid
SMILESC5=C(C1=CN=CC=C1)N=C(NC2=C(C=CC(=C2)NC(C3=CC=C(C=C3)CN4CCN(CC4)C)=O)C)N=C5
InChIInChI=1S/C29H31N7O/c1-21-5-10-25(18-27(21)34-29-31-13-11-26(33-29)24-4-3-12-30-19-24)32-28(37)23-8-6-22(7-9-23)20-36-16-14-35(2)15-17-36/h4-13,18-19H,14-17,20H2,1-2H3,(H,32,37)(H,31,33,34)
InChIKeyKTUFNOKKBVMGRW-UHFFFAOYSA-N
SafetyPhrasesClassification:Acutetoxicity,Oral(Category4),H302SafetyPhrases:S22-Donotbreathedust.S24/25-Avoidcontactwithskinandeyes.S36/37/39-Wearsuitableprotectiveclothing,glovesandeye/faceprotection.Hazardstatements:H302Harmfulifswallowed.Precautionarystatements:P264Washskinthoroughlyafterhandling.P270Donoteat,drinkorsmokewhenusingthisproduct.P301+P312IFSWALLOWED:CallaPOISONCENTERordoctor/physicianifyoufeelunwell.P330Rinsemouth.P501Disposeofcontents/containertoanapprovedwastedisposalplant.
CiteThisProductImatinibmesylate(StressMarqBiosciencesInc.,VictoriaBCCANADA,Catalog#SIH-453)

BIOLOGicalDescription

AlternativeNames4-[(4-Methyl-1-piperazinyl)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]-phenyl]benzamidemethanesulfonate,4-[(4-Methylpiperazin-1-yl)methyl]-N-(4-methyl-3-{[4-(pyridin-3-yl)pyrimidin-2-yl]amino}phenyl)benzamidemesylate,CGP57148,Genfatinib,Glivec,Imatinibmethanesulfonate,STI-571
ResearchAreasCancer,Apoptosis,CancerGrowthInhibitors,CellSignaling,TyrosineKinaseInhibitors
PubChemID5291
ScientificBackgroundImatinibmesylateisatyrosinekinaseinhibitor.ItspecificallyinhibitsBcr-Abltyrosinekinase,andreceptortyrosinekinasesencodedbyc-kitandplatelet-derivedgrowthfactorreceptor(PDGFR)oncogenes.
References1.KantarjianH.,etal.(2002).N.E.J.Med.346(9):645–652.

ProductImages

<p>Chemical structure of Imatinib mesylate (SIH-453), a BCR-ABL kinase inhibitor. CAS #: 152459-95-5. Molecular Formula: C30H35N7O4S. Molecular Weight: 589.7 g/mol.</p>

ChemicalstructureofImatinibmesylate(SIH-453),aBCR-ABLkinaseinhibitor.CAS#:152459-95-5.MolecularFormula:C30H35N7O4S.MolecularWeight:589.7g/mol.

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品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究,同时在其他领域也取得了一定成就,包括翻译后修饰,提供甲基化与乙酰基化抗体。其中,细胞应激领域主要包括热休克蛋白(HSP)领域。我们公司不仅在热休克蛋白领域领先全球,而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列,分别涉及抗体、蛋白、酶联免疫吸附试验(ELISA)试剂盒及小分子领域。